1.
Acta Med Port
; Suppl 1: 19S-23S, 1989 Sep.
Article
in Portuguese
| MEDLINE
| ID: mdl-2694770
ABSTRACT
Pharmacological aspects of presently used insulins are reviewed. A discussion of different forms of insulin therapy in insulin dependent and non insulin dependent diabetes mellitus is presented.
Subject(s)
Diabetes Mellitus, Type 1/drug therapy , Diabetes Mellitus, Type 2/drug therapy , Insulin Resistance , Insulin/therapeutic use , Humans , Insulin/pharmacokinetics , Insulin/pharmacology
2.
Acta Med Port
; 2(4-5): 231-3, 1989.
Article
in Portuguese
| MEDLINE
| ID: mdl-2694797
ABSTRACT
The author reviews the etiopathogeny of autoimmune thyroiditis: sequestered antigen, clonal selection, acquired tolerance with low doses of antigen and disordered immunoregulation. The main thyroid autoantibodies, their characteristics and functions are described. The genetic susceptibility associated to HLA antigen as well as the importance of inappropriate expression in thyroid epithelium are also pointed out. The experimental autoimmune thyroiditis, induced or spontaneous is shown as a model to the study of human autoimmune thyroiditis.