ABSTRACT
SIGNIFICANCE: Diabetic retinopathy is a common cause of blindness in individuals younger than 60 years. Screening for retinopathy is undertaken using conventional color fundus photography and relies on the identification of hemorrhages, vascular abnormalities, exudates, and cotton-wool spots. These can sometimes be difficult to identify. PURPOSE: Multicolor scanning laser imaging, a new imaging modality, may have a role in improving screening outcomes, as well as facilitating treatment decisions. METHODS: Observational case series comprising two patients with known diabetes who were referred for further examination after color fundus photography revealed abnormal findings. Multicolor scanning laser imaging was undertaken. Features of retinal disease from each modality were compared. RESULTS: Multicolor scanning laser imaging provides superior visualization of retinal anatomy and pathology, thereby facilitating risk stratification and treatment decisions. CONCLUSIONS: Multicolor scanning laser imaging is a novel imaging technique offering the potential for improving the reliability of screening for diabetic retinopathy. Validation studies are warranted.
Subject(s)
Diabetic Retinopathy/diagnosis , Microscopy, Confocal/methods , Retina/pathology , Adult , Humans , Male , Middle Aged , Retinal DiseasesABSTRACT
We report a case of a patient with treated breast cancer whose dilated fundus examination showed crystalline deposits in the central region of the macula. She was taking tamoxifen for secondary prevention. Optical coherence tomography revealed individual refractile deposits associated with intraretinal cysts in both eyes. Tamoxifen-related retinopathy was suspected. A decision to discontinue treatment with tamoxifen was considered but had to be taken in conjunction with the oncologist.
