ABSTRACT
A symptomatic pancreatic mass poses both a diagnostic and therapeutic conundrum. First, benign conditions may mimic malignancy and second, the management of benign lesions has not been well defined. We reviewed four such cases and discuss the management of juvenile idiopathic fibrosing pancreatitis in the light of these. In four children with symptomatic pancreatic masses/enlargement (three with jaundice) all resolved spontaneously without definitive intervention. Histopathology, obtained in two cases, revealed a fibrotic chronic inflammatory reaction. Pancreatic masses in children may not be malignant. Resolution of symptoms including obstructive jaundice and a mass secondary to juvenile idiopathic fibrosing pancreatitis may occur spontaneously, avoiding the need for resection or definitive drainage procedures.
Subject(s)
Fibrosis/diagnosis , Pancreatic Neoplasms/diagnosis , Pancreatitis/diagnosis , Abdominal Pain/etiology , Adolescent , Biopsy , Child , Child, Preschool , Diagnosis, Differential , Female , Fibrosis/complications , Follow-Up Studies , Humans , Jaundice, Obstructive/etiology , Male , Pancreas/diagnostic imaging , Pancreas/pathology , Pancreatic Neoplasms/complications , Pancreatitis/complications , Remission, Spontaneous , Tomography, X-Ray Computed , UltrasonographyABSTRACT
Acute pancreatitis is a common disease. As knowledge of its pathophysiology improves, evidence is found to confirm and refute present management and also to suggest new approaches. This article addresses some of these areas in the context of the management of acute pancreatitis.