ABSTRACT
The clinical practice of endodontic therapy is relatively common, especially in the anterior of the mouth, with easy access to cavities and in cases of mechanical debridement. However, problems such as perforation of the root canal can occur during treatment, and can cause periodontal tissue damage and esthetic problems. The treatment of root canal perforation consists of periodontal and endodontic therapy, as well as selecting the best material for perforation repair. This is a case report of iatrogenic root perforation on an anterior tooth that required combined restorative, periodontal, surgical, and endodontic approaches. The case describes the use of a subepithelial connective tissue graft (SCTG) on a resin ionomer-restored root surface for the treatment of root perforation and periodontal damage caused by an iatrogenic procedure, with a 12-month follow-up. This case report shows that SCTG can successfully treat root perforations associated with a resin ionomer-restored root surface.
Subject(s)
Glass Ionomer Cements , Resin Cements , Connective Tissue/transplantation , Glass Ionomer Cements/therapeutic use , Humans , Root Canal Therapy , Tooth Root/surgeryABSTRACT
Pemphigus vulgaris (PV) is an autoimmune intra-epithelial dermatologic disease that is characterized by epithelial blistering and affected cutaneous and/or mucosal surfaces. The disease is caused by circulating immunoglobulin G (IgG) antibodies directed against desmosomes. These antibodies interfere with keratinocyte adhesion, causing acantholysis, which results in blister formation. At present, death from pemphigus infection is unusual; however, morbidity and mortality from chronic corticosteroid use remain considerable, indicating a need for additional therapies. This article presents a case of PV in a female patient that was treated with conventional corticosteroid therapy and discusses recent adjuvant therapy.
Subject(s)
Mouth Diseases/drug therapy , Pemphigus/drug therapy , Adult , Anti-Inflammatory Agents/therapeutic use , Autoimmune Diseases/drug therapy , Autoimmune Diseases/surgery , Combined Modality Therapy , Dexamethasone/therapeutic use , Female , Follow-Up Studies , Glucocorticoids/therapeutic use , Humans , Mouth Diseases/pathology , Mouth Diseases/surgery , Mouthwashes/therapeutic use , Pemphigus/pathology , Pemphigus/surgery , Prednisone/therapeutic useABSTRACT
Neste estudo foi investigada a ação antimicrobiana e a inibição de aderência in vitro do extrato hidroalcoólico de Rosmarinus officinalis Linn. (alecrim) sobre cepas padrão de Streptococcus mitis ATCC 98811, Streptococcus sanguinis ATCC 10556, Streptococcus mutans ATCC 25175, Streptococcus sobrinus ATCC 27609 e Lactobacillus casei ATCC 7469. Os ensaios foram realizados pelas técnicas de ágar-difusão em placas de Petri para determinação da Concentração Inibitória Mínima (CIM) e técnica de tubos inclinados para determinação da Concentração Inibitória Mínima de Aderência (CIMA) ao vidro, na presença de 5 por cento de sacarose. Os mesmos procedimentos foram realizados com a clorexidina à 0,12 por cento. As CIMs (mg/mL) do extrato de Rosmarinus officinalis sobre S. sanguinis ATCC 10556, S. mutans ATCC 25175, S. sobrinus ATCC 27609 e L. casei ATCC 7469 foram 1:1, 1:4, 1:1 e 1:4, respectivamente. Não houve inibição de crescimento de S. mitis ATCC 98811. As CIMAs do extrato de Rosmarinus officinalis frente a S. mitis ATCC 98811, S. mutans ATCC 25175 e S. sobrinus ATCC foram 1:8, 1:16 e 1:8, nessa ordem. Os resultados sugerem a possibilidade de uso do extrato de alecrim como antimicrobiano oral. No entanto, modelos de estudo que possam reproduzir situações mais próximas àquelas encontradas na cavidade oral são requeridas para avaliação de agentes antimicrobianos no tratamento e prevenção de infecções orais biofilme-dependentes.
In this study was investigated the antimicrobial activity and in vitro adherence inhibition of a hydro alcoholic Rosmarinus officinalis Linn. (alecrim) on standard strains of Streptococcus mitis ATCC 98811, Streptococcus sanguinis ATCC 10556, Streptococcus mutans ATCC 25175, Streptococcus sobrinus ATCC 27609 and Lactobacillus casei ATCC 7469 extract. The test was carried out by inundation tecniques in Petri dishes to determine the Minimum Inhibitory Concentration (MIC) and inclined tubes techniques the Minimum Inhibitory Concentration of Adherence to glass (MICA) at the presence of 5 percent sucrose. Tests with gluconate of chlorexidine 0.12 percent were performed as controls. MICs of the Rosmarinus officinalis extract dilutions (mg/mL) against S. sanguinis ATCC 10556, S. mutans ATCC 25175, S. sobrinus ATCC 27609 and L. casei ATCC 7469 were 1:1, 1:4, 1:1 e 1:4, respectively. The extract from alecrim inhibited all the standard strains growth tested, except for S. mitis ATCC 98811. MICAs of the Rosmarinus officinalis extract dilutions (mg/mL) against S. mitis ATCC 98811, S. mutans ATCC 25175 e S. sobrinus ATCC were 1:8, 1:16 e 1:8, respectively. The results suggest that there is a possibility of the alecrim use as an oral antimicrobial. Nevertheless, study models which could reproduce situations similar to those seen in bucal caries are necessary for the antimicrobial agents evaluation in the treatment and biofilm dependant oral infections prevention.
ABSTRACT
Os autores relatam um caso de sialolitíase de glândulas salivares menores presente no lábio superior de um paciente adulto do sexo masculino, o qual, clinicamente, assemelhava-se a um mucocele. A lesäo foi diagnosticada e tratada na Clínica de Estomatologia do Curso de Mestrado em Odontologia da Universidade Federal da Paraíba (UFPB)
