ABSTRACT
Soybean plants of the variety 'MG/BR Conquista' were grown in open top chambers, simulating elevated CO2 concentration ([CO2]) and high temperature under the following treatments: 1) ambient [CO2] and ambient temperature (Amb); 2) elevated [CO2] (eCO2) and ambient temperature (Elev); 3) ambient [CO2] and high temperature (Amb/Temp); 4) elevated CO2 and high temperature (Elev/Temp). The aim was to evaluate responses to elevated [CO2] and high temperature, with focus on plant development and seed yield, and composition. Elev stimulated grain yield and Amb/Temp had opposite effect. Several biochemical parameters were affected by Amb/Temp, most of them reversed by simultaneous application of Elev. The oil obtained with Elev/Temp had lower degree of unsaturation. A network of relationships among biochemical parameters of grains at three developmental stages revealed that Amb/Temp and Elev/Temp affect significantly both carbohydrate and lipid metabolisms. No significant difference was obtained comparing networks corresponding to Amb and Elev/Temp.
Subject(s)
Biomass , Carbon Dioxide/pharmacology , Glycine max/drug effects , Carbohydrates/chemistry , Carbon/chemistry , Carbon/metabolism , Edible Grain/metabolism , Fatty Acids/chemistry , Fatty Acids/metabolism , Nitrogen/chemistry , Nitrogen/metabolism , Seeds/drug effects , Seeds/metabolism , Glycine max/chemistry , Glycine max/metabolism , TemperatureABSTRACT
Introdução: o câncer de colo uterino é a segunda neoplasia mais comum em mulheres no mundo e a terceira entre a população feminina brasileira. O HPV desempenha um importante papel no desenvolvimento de neoplasias cervicais, estando presente em 95% dos casos de câncer de colo de útero. O carcinoma de células glassy é um carcinoma adenoescamoso misto pouco diferenciado, raro, de comportamento agressivo e altamente resistente à radioterapia. Atinge tipicamente mulheres jovens, com pico de incidência entre a 3a e a 4a década de vida. Está associado aos tipos 16 e 18 de HPV e sua evolução é aceleradana gravidez. O tempo médio de sobrevida após o diagnóstico é de 10 meses. Relato de caso: mulher, 26 anos, multípara, com história prévia de condiloma acuminado, apresentou lesões genitais que agravaram em sua última gestação, tendo evoluído com massas exofíticas diagnosticadas como carcinoma de células glassy, com curso agressivo e metástases precoces, não responsivo à radioterapia e progressão ao óbito em 16 meses. Conclusão: o carcinoma de células glassy destaca-se pela agressividade e rapidez de seu desenvolvimento, levando ao óbito mulheres jovens, em idade fértil e produtiva. Diante da sua baixa resposta às terapias antineoplásicas, destaca-se a importância de sua prevenção, seu diagnóstico e tratamento precoces, possíveis mediante o usode preservativos, da vacina contra o HPV e do exame colpocitológico regular, com coleta de material endocervical e acompanhamento eficaz.
Introduction: cervical cancer is the second most common cancer in women worldwide and the third among the female population in Brazil. HPV plays an important role in the development of cervical cancer, being present in 95% of cases of cancer of the cervix. Glassy cells carcinoma is a poorly differentiated mixed adenosquamous carcinoma, rare, aggressive and highly resistant to radiotherapy. It typically affects young women, with peak incidence between the third and fourth decades of life. It is associated with types 16 and 18 of HPV and its evolution is acelerated during pregnancy. The average survival time after diagnosis is 10 months.Case Report: woman, 26 years old, multiparous, with a history of condyloma acuminata, genital lesions that had increased in their last pregnancy, having evolved with exophytic masses diagnosed as glassy cell carcinoma, and aggressive course with early metastases not responsive to radiation therapy and progression to death in 16 months. Conclusion: glassy cells carcinoma is distinguished by aggressiveness and speed of its development, leading child-bearing age and productive young women to death. In view of its low response to anticancer therapies, we highlight the importance of its prevention, early diagnosis and treatment, possible through the use of condoms, the vaccine against HPV and cervical cytology at regular collection of endocervical material and effective monitoring.
