Subject(s)
Anesthesia Department, Hospital , Anesthesiology , Medical Staff, Hospital/supply & distribution , Medically Underserved Area , Physicians/supply & distribution , Anesthesiology/education , Data Collection , Forecasting , Hospital Administrators , Humans , Internship and Residency/statistics & numerical data , Middle Aged , Physician Assistants/supply & distribution , Retirement , Spain , Surveys and Questionnaires , WorkforceABSTRACT
No disponible
Subject(s)
Middle Aged , Humans , Medically Underserved Area , Spain , Physician Assistants , Physicians , Retirement , Surveys and Questionnaires , Data Collection , Anesthesiology , Anesthesia Department, Hospital , Medical Staff, Hospital , Hospital Administrators , Internship and Residency , ForecastingABSTRACT
The study evaluates the analgesic effects of epidural clonidine in patients undergoing abdominal hysterectomy under combined epidural/general anaesthesia. Forty ASA 1-2 patients were divided into two groups who received epidurally either clonidine 300 micrograms (group 1) or placebo (group 2). Anaesthesia was maintained with oxygen/nitrous oxide, a midazolam infusion, vecuronium, and boluses of fentanyl 100 micrograms administered as needed to maintain cardiovascular stability. The mean (SD) intraoperative fentanyl requirements were 2.05 (0.18) and 3.66 (0.3) micrograms.kg-1.h-1 for groups 1 and 2 respectively (p < 0.001). Patients in Group 1 had a lower heart rate after tracheal intubation and surgical incision (p < 0.02). In the recovery room, pain intensity was lower in group 1 (p < 0.003) and the mean (SD) time until analgesia request was increased from 48.5 (8.4) min in group 2 to 235.7 (33.2) min in group 1 (p < 0.001). Our results demonstrate that epidural clonidine produces decreased fentanyl requirements, improved cardiovascular stability, reduced pain intensity and effective postoperative analgesia in the recovery room.
