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1.
Food Nutr Bull ; 34(2): 123-30, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23964385

ABSTRACT

BACKGROUND: Exclusive breastfeeding (EBF) in adolescent mothers has been associated with greater postpartum maternal weight loss. OBJECTIVE: To assess the associations between EBF and weight loss in adolescent and adult mothers and between EBF and weight and length gain of their children. METHODS: A cohort of 68 adolescent mothers (15 to 19 years), 64 adult mothers (20 to 29 years), and their infants were studied. Anthropometric measurements were performed at 15, 90, 180, and 365 days postpartum in the mothers and children. EBF was defined as consumption of human milk without supplementation of any type (water, juice, nonhuman milk, or food) for 4 months. RESULTS: Sixty-five percent of mothers sustained EBF for 4 months. There were no significant differences in the weight or length of the infants of adolescent and adult mothers at 365 days postpartum. Among infants of adult mothers, there was a significant difference between the weight gain of those were exclusively breastfed and those who were not exclusively breastfed (6,498 +/- 1,060 vs 6,096 +/- 1,035 g, p < .050) at 365 days postpartum, according to the parameters for weight gain and length established by the World Health Organization (WHO). Among both adult and adolescent mothers, those who practiced EBF lost more weight than those who did not practice EBF (-2.9 kg, 95% interquartile range, -5.7 to 0.8 kg, vs -1.8 kg 95% interquartile range -2.8 to 2.2 kg; p = .004). Gestational weight gain, duration of EBF, and recovery menstruation explained 21% of the variance (F = 28.184, p = .001) in change in postpartum maternal weight (in kilograms) from 0 to 365 days postpartum in all mothers. Pregestational weight, duration of EBF, and maternal age were factors that explained 14% (F = 22.759, p = .001) of the change in the weight and length of the infants from 0 to 365 days of life. CONCLUSIONS: EBF in adolescent and adult mothers influences postpartum weight loss and provides adequate infant growth in accordance with the WHO 2006 standards.


Subject(s)
Breast Feeding , Weight Loss/physiology , Adolescent , Adult , Body Height , Body Weight , Child Development , Female , Humans , Infant , Infant, Newborn , Mexico/epidemiology , Obesity/epidemiology , Overweight/epidemiology , Postpartum Period , Pregnancy , Pregnancy in Adolescence , Thinness/epidemiology , Young Adult
2.
Reprod Toxicol ; 34(1): 125-32, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22507748

ABSTRACT

UNLABELLED: Universal prenatal daily supplementation with iron (60-120mg iron) plus folic acid (0.4mg), as recommended by INACG/WHO/UNICEF, prevents anemia where iron deficiency is prevalent but may be excessive for non-anemic women. Weekly supplementation with 120mg iron plus various amounts of folic acid similarly prevents significant anemia. OBJECTIVE: Determine, in non-anemic pregnant women, if oxidative stress is produced by recommended daily or weekly supplementation schemes. PROCEDURE: 100 non-anemic pregnant women, 30% iron-deficient at week 20, were randomly supplemented daily followed by weekly, each for 8 weeks, or in reversed order. RESULTS: With daily supplementation thio-barbituric-acid-reacting-substances (TBARS) increased significantly and high serum ferritin, iron, and excessively elevated hemoglobin occurred near term. During weekly supplementation significant anemia and high iron parameters were prevented, and elevated TBARS declined. CONCLUSION: In non-anemic pregnant women both schemes prevented significant anemia. Oxidative stress occurred only during daily supplementation periods. Weekly supplementation appears safer.


Subject(s)
Dietary Supplements , Folic Acid/administration & dosage , Iron/administration & dosage , Pregnancy/blood , Vitamin B 12/administration & dosage , Adolescent , Adult , Drug Administration Schedule , Female , Ferritins/blood , Humans , Iron/blood , Mexico , Oxidative Stress/drug effects , Thiobarbituric Acid Reactive Substances/analysis , Young Adult
3.
Am J Hum Biol ; 24(4): 425-31, 2012.
Article in English | MEDLINE | ID: mdl-22344621

ABSTRACT

OBJECTIVE: To evaluate changes in weight and body fat of Mexican adolescent compared to those of adult lactating women from the Northwest (NM) and Central (CM) regions of Mexico in the first trimester postpartum. METHODS: A prospective design was used to evaluate 41 exclusively breastfeeding women (21 adolescents and 20 adults) recruited 1-2 days after delivering a healthy singleton at the Hospital Infantil del Estado de Sonora (Northwest Mexico) and Instituto Nacional de Perinatología, in Mexico City. Socioeconomic status, height, body weight and composition, dietary intake, physical activity, and milk volume (quantified by deuterium dilution method) were measured at the 1st and 3rd month postpartum. RESULTS: Women did not lose weight throughout the first trimester postpartum. Mean postpartum weight retention at the end of the study was 3.8 kg. No differences in weight and body mass index (BMI) were found between adolescent and adult women in both periods. Energy and macronutrient intakes, physical activity and milk volume were similar between the two groups of women. In both periods, adolescents from the CM region had lower weight, BMI, and body fat than adolescents from the NM region (P<0.05). At the 3rd month, pregestational weight (P < 0.0001) was a predictor of BMI, and region (P < 0.05) and milk volume (P < 0.01) were associated with percentage of body fat. CONCLUSIONS: Exclusively breastfeeding for 3 months did not reduce weight or body fat in the Mexican population of this study. Efforts to avoid weight retention in the lactation period may contribute to prevent overweight and obesity in women.


Subject(s)
Adipose Tissue/metabolism , Body Weight , Breast Feeding , Lactation , Young Adult , Adolescent , Adult , Anthropometry , Body Composition , Body Mass Index , Female , Humans , Mexico , Prospective Studies , Time Factors
4.
Salud Publica Mex ; 53(1): 2-10, 2011.
Article in Spanish | MEDLINE | ID: mdl-21340134

ABSTRACT

OBJECTIVE: To analyze the pattern of bone mineral density (BMD), serum concentrations of estradiol and calcium levels, dietary calcium, body mass index (BMI), and lactation in adolescents and adult women at 15, 90, and 365 postpartum days (ppd). MATERIAL AND METHODS: A prospective cohort study was conducted of 33 adolescents and 39 adult women. Anthropometric and dietetic evaluations were performed, as well as evaluations of bone mineral density in L2-L4 and femur neck. Estradiol concentrations and calcium serum levels were determined. RESULTS: L2-L4 BMD increased by 16% in adolescents, and 3% in adult women from day 15 to 365 ppd. While age was associated with this change (ß=13.779, EE=3.5, p=0.001), lactation was not (ß=-0.705, EE=0.647, p=0.283). The adult women had a higher L2-L4 BMD at 15, 90, and 635 ppd (1.151 vs 0.978 g/cm², 1.195 vs 1.070 g/cm², 1.195 vs 1.123 g/cm², respectively) (p<0.003). CONCLUSIONS: Adolescents' BMD increased three times more than that of adult women. For all women, BMD was dependent of age and independent of lactation.


Subject(s)
Bone Density , Postpartum Period/physiology , Adolescent , Adult , Age Factors , Body Mass Index , Bone Demineralization, Pathologic/blood , Bone Demineralization, Pathologic/epidemiology , Bone Demineralization, Pathologic/physiopathology , Calcium/blood , Calcium, Dietary/pharmacokinetics , Child , Estradiol/blood , Female , Follow-Up Studies , Humans , Lactation/blood , Lactation/physiology , Postpartum Period/blood , Pregnancy , Pregnancy in Adolescence/statistics & numerical data , Prospective Studies , Young Adult
5.
Salud pública Méx ; 53(1): 2-10, Jan.-Feb. 2011. tab
Article in Spanish | LILACS | ID: lil-574958

ABSTRACT

OBJETIVO: Analizar el patrón de la densidad mineral ósea (DMO), calcio y estradiol séricos, consumo de calcio, índice de masa corporal (IMC) y lactancia en adolescentes y adultas a 15, 90 y 365 días posparto (dpp). MATERIAL Y MÉTODOS: Cohorte prospectivo en 33 adolescentes y 39 adultas con evaluación antropométrica, dietética y ósea en L2-L4 y cuello de fémur; bioquímica con estradiol y calcio séricos. RESULTADOS: Las adolescentes aumentaron de los 15 a los 365 dpp 16 por ciento su DMO de L2-L4, las adultas 3 por ciento. La edad se asoció a este cambio (β=13.779, EE=3.5, p=0.001); la lactancia no se asoció (β=-0.705, EE=0.647, p=0.283). Las adultas presentaron mayor DMO de L2-L4 a 15, 90 y 365 dpp respectivamente (1.151vs 0.978g/cm², 1.195vs1.070g/cm², 1.195vs1.123g/cm², p<0.003). CONCLUSIONES: Las adolescentes incrementaron su DMO tres veces más que las adultas. El cambio en la DMO fue dependiente de la edad e independiente de la práctica de lactancia.


OBJECTIVE: To analyze the pattern of bone mineral density (BMD), serum concentrations of estradiol and calcium levels, dietary calcium, body mass index (BMI), and lactation in adolescents and adult women at 15, 90, and 365 postpartum days (ppd). MATERIAL AND METHODS: A prospective cohort study was conducted of 33 adolescents and 39 adult women. Anthropometric and dietetic evaluations were performed, as well as evaluations of bone mineral density in L2-L4 and femur neck. Estradiol concentrations and calcium serum levels were determined. RESULTS: L2-L4 BMD increased by 16 percent in adolescents, and 3 percent in adult women from day 15 to 365 ppd. While age was associated with this change (β=13.779, EE=3.5, p=0.001), lactation was not (β=-0.705, EE=0.647, p=0.283). The adult women had a higher L2-L4 BMD at 15, 90, and 635 ppd (1.151 vs 0.978g/cm², 1.195 vs 1.070g/cm², 1.195 vs 1.123g/cm², respectively) (p<0.003). CONCLUSIONS: Adolescents' BMD increased three times more than that of adult women. For all women, BMD was dependent of age and independent of lactation.


Subject(s)
Adolescent , Adult , Child , Female , Humans , Pregnancy , Young Adult , Bone Density , Postpartum Period/physiology , Age Factors , Body Mass Index , Bone Demineralization, Pathologic/blood , Bone Demineralization, Pathologic/epidemiology , Bone Demineralization, Pathologic/physiopathology , Calcium, Dietary/pharmacokinetics , Calcium/blood , Estradiol/blood , Follow-Up Studies , Lactation/blood , Lactation/physiology , Postpartum Period/blood , Pregnancy in Adolescence/statistics & numerical data , Prospective Studies
6.
Rev Invest Clin ; 63(5): 500-8, 2011.
Article in Spanish | MEDLINE | ID: mdl-22468480

ABSTRACT

INTRODUCTION: The excessive gestational weight gain predisposes to overweight and obesity postpartum, this becomes a worldwide public health problem. OBJECTIVE: To analyze gestational weight pattern and body fat in adolescents and adult women, to identify the group that would have major weight and body fat gain. MATERIAL AND METHODS: A prospective cohort study done in 64 adolescent < or = 18 years and 48 adult women. Anthropometric evaluation was realized, at 20, 24, 28, 32, 36 and 38 gestational weeks with weight and body fat percentage. Patients signed letter informed consent. RESULTS: In adolescents weight and BMI were smaller (p < 0.001), and their gestational fat gain was bigger than in the adult women (5.31 vs. 4.12 kg; p < 0.001). Pre-gestational BMI (beta = 0.459, EE = 0.089, p = 0.001), and age group (beta = - 1.400, EE = 0.735, p = 0.060) were associated to fat percentage variability. The adolescents with low weight and BMI > or = 85th percentile showed a greater gain of weight in respect to which is classified as normal weight (18.0 and 15.5 vs. 12.0 kg; p = 0.018). 54.7% of the adolescents and 64.6% of adults did gain excessive weight, more than the recommended according pre-gestational BMI. CONCLUSIONS: Age and pregestational BMI conditioned the body fat change. More than half of the patients included exceeded the recommended weight gain. The overweight or excessive weight gain adolescents have increased risk of postpartum retention weight than adult women in the same conditions.


Subject(s)
Adipose Tissue/growth & development , Body Mass Index , Pregnancy/physiology , Weight Gain , Adolescent , Adult , Age Factors , Female , Humans , Prospective Studies
7.
An. venez. nutr ; 23(1): 5-9, jun. 2010. tab, graf
Article in Spanish | LILACS, LIVECS | ID: lil-630283

ABSTRACT

La anemia de origen nutricio afecta a un tercio de las mujeres en edad reproductiva a nivel mundial y puede deberse a la deficiencia de uno o varios nutrimentos involucrados en la hematopoyesis, principalmente el hierro. Las mujeres constituyen un grupo en riesgo dadas las pérdidas menstruales. Por ello, el objetivo de este trabajo fue evaluar la relación entre la percepción de cantidad de flujo menstrual y las deficiencias de hierro, folato y vitamina B12 en una muestra de mujeres de la Ciudad de México. Se realizó un estudio transversal, con mujeres de 12 a 49 años, no embarazadas ni amamantando. Se midieron las concentraciones de hemoglobina, ferritina, hierro y vitamina B12 en suero y ácido fólico eritrocitario. La cantidad de flujo menstrual percibida se examinó con una escala analógica visual de 10 cm de longitud. Las asociaciones se evaluaron mediante las pruebas T de Student, Chi² y el coeficiente de correlación de Pearson. La sensibilidad y especificidad se representaron en una curva ROC. Los resultados mostraron que las anémicas tuvieron una percepción de la cantidad de flujo menstrual significativamente mayor que las no anémicas (p<0.05). No se observaron diferencias en las calificaciones informadas por las mujeres con deficiencias de otros nutrimentos y aquellas sin deficiencias. La escala analógica visual propuesta en este trabajo puede ser utilizada en poblaciones sanas como una herramienta subjetiva de tamizaje para el riesgo de padecer anemia, que además es fácil de contestar y económica(AU)


Nutritional anaemias affect more than one third of women of reproductive age worldwide as a result of a lack of one or various nutrients involved in the haematopoiesis, mainly iron. Women are at higher risk because of menstruation. The objective of this paper was to evaluate the association between the perception of the amount of menstrual bleeding and iron, folic acid, vitamin B12, ferritin and hemoglobin deficiencies, among women from Mexico City. This cross-sectional study included 12-49 year old women, that were not pregnant or breastfeeding. Hemoglobin, ferritin, iron, folate, and vitamin B12 were quantified. Self reported menstrual bleeding was estimated by using a 10 cm long visual analogue scale. Associations were calculated by Student’s T test, Chi2 and Pearson’s correlation coefficient. Sensibility and specificity were depicted in a ROC curve. Results showed that anaemic women perceived a larger menstrual blood loss than those non anaemic (p<0.05). No differences were observed in any other of the micronutrients studied.The visual analogue scale is an easy-to-answer and cheap screening test that could be used in apparently healthy populations to detect the risk of anaemia(AU)


Subject(s)
Humans , Female , Vitamin B 12/administration & dosage , /complications , Folic Acid/administration & dosage , Menstrual Cycle/physiology , Anemia, Iron-Deficiency , Nutritional Sciences
8.
Reprod Biol Endocrinol ; 7: 54, 2009 May 28.
Article in English | MEDLINE | ID: mdl-19476631

ABSTRACT

BACKGROUND: Oxidative stress has been identified in the peritoneal fluid and peripheral blood of women with endometriosis. However, there is little information on the antioxidant intake for this group of women. The objectives of this work were 1) to compare the antioxidant intake among women with and without endometriosis and 2) to design and apply a high antioxidant diet to evaluate its capacity to reduce oxidative stress markers and improve antioxidant markers in the peripheral blood of women with endometriosis. METHODS: Women with (WEN, n = 83) and without endometriosis (WWE, n = 80) were interviewed using a Food Frequency Questionnaire to compare their antioxidant intake (of vitamins and minerals). Then, the WEN participated in the application of a control (n = 35) and high antioxidant diet (n = 37) for four months. The high antioxidant diet (HAD) guaranteed the intake of 150% of the suggested daily intake of vitamin A (1050 microg retinol equivalents), 660% of the recommended daily intake (RDI) of vitamin C (500 mg) and 133% of the RDI of vitamin E (20 mg). Oxidative stress and antioxidant markers (vitamins and antioxidant enzymatic activity) were determined in plasma every month. RESULTS: Comparison of antioxidant intake between WWE and WEN showed a lower intake of vitamins A, C, E, zinc, and copper by WEN (p < 0.05, Mann Whitney Rank test). The selenium intake was not statistically different between groups. During the study, the comparison of the 24-hour recalls between groups showed a higher intake of the three vitamins in the HAD group. An increase in the vitamin concentrations (serum retinol, alpha-tocopherol, leukocyte and plasma ascorbate) and antioxidant enzyme activity (superoxide dismutase and glutathione peroxidase) as well as a decrease in oxidative stress markers (malondialdehyde and lipid hydroperoxides) were observed in the HAD group after two months of intervention. These phenomena were not observed in the control group. CONCLUSION: WEN had a lower intake of antioxidants in comparison to WWE. Peripheral oxidative stress markers diminished, and antioxidant markers were enhanced, in WEN after the application of the HAD.


Subject(s)
Antioxidants/administration & dosage , Antioxidants/metabolism , Biomarkers/blood , Endometriosis/diet therapy , Endometriosis/metabolism , Adult , Female , Follow-Up Studies , Fruit , Glutathione Peroxidase/metabolism , Humans , Leukocytes/metabolism , Nutrition Assessment , Oxidative Stress/drug effects , Oxidative Stress/physiology , Reactive Nitrogen Species/blood , Reactive Oxygen Species/blood , Superoxide Dismutase/metabolism , Vegetables , Vitamin A/blood , alpha-Tocopherol/blood
9.
Med Sci Monit ; 14(12): CR598-603, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19043366

ABSTRACT

BACKGROUND: The aim of the study was to determine whether a predictive value for the diagnosis of gestational diabetes mellitus (GDM) could be established using different glucose screening test thresholds in Mexican urban pregnant women. MATERIAL/METHODS: A group of 635 pregnant women (12-33 weeks of gestation) with serum glucose screening values of > or = 7.2 mmol (> or = 130 mg/dl) were evaluated with a 100-g 3-h oral glucose tolerance test (OGTT). The positive predictive values (PPVs) for serum glucose screening values of > or = 7.2 mmol to > or = 11.1 mmol (> or = 130 to > or = 200 mg/dl), age, and pregestational BMI were calculated. RESULTS: Of the women, 304 (47.8%) had a normal OGTT, 126 (19.8%) had impaired glucose tolerance, and 205 (32.3%) had GDM. A serum glucose screening value of > or = 9.4 mmol (> or = 170 mg/dl) had a positive predictive value (PPV) of 0.85 and the relative risk for GDM was 6.62 (95%CI: 4.40-9.97, p=0.001). Omission of the 3-h value during OGTT yielded a sensitivity of 91.2% (187/205). CONCLUSIONS: In this group of Mexican urban pregnant women, a serum glucose screening value of > or = 9.4 mmol (> or = 170 mg/dl) had a PPV of 85%. An algorithm is proposed to reduce the number of OGTTs performed in pregnant women attending prenatal care by 36.2%.


Subject(s)
Diabetes, Gestational/diagnosis , Mass Screening/methods , Urban Population , Algorithms , Blood Glucose/analysis , Female , Glucose Tolerance Test , Humans , Mexico , Pregnancy
10.
Salud pública Méx ; 50(6): 523-529, nov.-dic. 2008. ilus, tab
Article in Spanish | LILACS | ID: lil-497461

ABSTRACT

En el campo de la salud las revisiones sistemáticas y el metaanálisis (MA) han cobrado auge, ya que permiten congregar estudios de características similares y generar indicadores que describan el riesgo o el beneficio de intervenciones clínicas asociadas a la presencia de un problema de salud. Para interpretar el MA y darle su justa dimensión, es necesario tomar en cuenta la racionalidad del marco teórico que lo sustenta, sus criterios metodológicos y la posible relación causal entre exposición y evento, además del contextualizar la información. Actualmente, un gran reto constituye el análisis y la síntesis de la mayor cantidad de información para tomar decisiones de manera rápida y asertiva Este artículo hace un breve recorrido por la racionalidad científica y su aplicación en la teoría causal en el marco de la epidemiología, para sentar los cimientos que permitan evaluar la pertinencia y validez de las decisiones que se tomen con base en estos análisis.


Currently, the challenge is to analyze and synthesize as much information as possible in order to make quick, correct decisions. Systematic reviews and meta-analysis have quickly arisen in the health field because they allow researchers to congregate studies of similar characteristics to generate estimators that describe the risk or benefit of practices related to health problems. To understand and attach the appropriate importance to meta-analyses, it is necessary to consider the rationale of the theoretical framework, the methodological criteria, and the possible causal relationship between exposure and outcome, besides contextualizing the information. This paper briefly explores scientific rationality and its application in causal theory within an epidemiological framework, to set the basis that allows decision-makers and health professionals to evaluate the appropriateness and validity of conclusions derived from this type of analyses.


Subject(s)
Causality , Clinical Trials as Topic , Meta-Analysis as Topic , Review Literature as Topic , Evidence-Based Medicine , Knowledge , Logic , Models, Theoretical
11.
Salud Publica Mex ; 50(6): 523-9, 2008.
Article in Spanish | MEDLINE | ID: mdl-19039442

ABSTRACT

Currently, the challenge is to analyze and synthesize as much information as possible in order to make quick, correct decisions. Systematic reviews and meta-analysis have quickly arisen in the health field because they allow researchers to congregate studies of similar characteristics to generate estimators that describe the risk or benefit of practices related to health problems. To understand and attach the appropriate importance to meta-analyses, it is necessary to consider the rationale of the theoretical framework, the methodological criteria, and the possible causal relationship between exposure and outcome, besides contextualizing the information. This paper briefly explores scientific rationality and its application in causal theory within an epidemiological framework, to set the basis that allows decision-makers and health professionals to evaluate the appropriateness and validity of conclusions derived from this type of analyses.


Subject(s)
Causality , Clinical Trials as Topic , Meta-Analysis as Topic , Review Literature as Topic , Evidence-Based Medicine , Knowledge , Logic , Models, Theoretical
12.
Ann Nutr Metab ; 52(2): 167-73, 2008.
Article in English | MEDLINE | ID: mdl-18446021

ABSTRACT

AIM: To determine the useful dosage of ascorbic acid and alpha-tocopherol against oxidative stress and DNA damage in the elderly. METHODS: A double-blind controlled clinical assay carried out in a sample of 66 healthy subjects divided into three age-paired random groups with 22 subjects in each group. Group A received placebo and group B was administered 500 mg of ascorbic acid and 400 IU of alpha-tocopherol, whereas group C received 1,000 mg of ascorbic acid and 400 IU of alpha-tocopherol for a 6-month period. The following measurements were performed before and after the 6-month treatment period: thiobarbituric acid reactive substances (TBARS); total antioxidant status (TAS); superoxide dismutase (SOD), and glutation peroxidase (GPx) and DNA damage by comet assay. RESULTS: After 6 months, group B subjects exhibited an increase in SOD and GPx enzyme levels; however, this was not statistically significant (p > 0.05). Likewise, TBARS and TAS concentrations remained unchanged (p > 0.05). In addition, in group C the decrease in TBARS and increase in SOD, GPx, and TAS were not statistically significant (p > 0.05). Similarly, average DNA migration showed no significant differences with high-dosage ascorbic acid and alpha-tocopherol. CONCLUSION: These findings suggest that administration of 1,000 mg of ascorbic acid plus 400 IU of alpha-tocopherol for 6 months is not useful for diminishing oxidative stress and DNA damage in healthy elderly adults.


Subject(s)
Antioxidants/therapeutic use , Ascorbic Acid/therapeutic use , DNA Damage/drug effects , Oxidative Stress/drug effects , alpha-Tocopherol/therapeutic use , Aged , Antioxidants/administration & dosage , Antioxidants/analysis , Ascorbic Acid/administration & dosage , Ascorbic Acid/blood , Double-Blind Method , Erythrocytes/enzymology , Female , Glutathione Peroxidase/blood , Humans , Lipid Peroxidation/drug effects , Male , Mexico , Middle Aged , Superoxide Dismutase/blood , Thiobarbituric Acid Reactive Substances/analysis , Treatment Failure , Urban Population , Vitamin E/blood , alpha-Tocopherol/administration & dosage
13.
Bol. méd. Hosp. Infant. Méx ; 65(2): 86-99, mar.-abr. 2008. ilus, tab
Article in Spanish | LILACS | ID: lil-701139

ABSTRACT

La escasez de hierro es la deficiencia nutricia específica más común en el mundo. En 2006, la prevalencia de anemia entre los niños en México fue de 37.8% en menores de 2 años, 20.0% de 2 a 5 años y 16.6% de 6 a 11 años. Aunque la ingestión de hierro total en niños de 1 a 4 años es adecuada (≈ 6.2 mg/día), la de hierro hemínico es baja y la de inhibidores de la absorción de hierro es muy alta, por lo que la biodisponibilidad general del hierro en la dieta es pobre (3.85%). Para tratar y prevenir la anemia se puede aumentar la ingestión de hierro biodisponible, mitigar sus pérdidas, y aumentar su reserva mediante la ligadura tardía del cordón umbilical. La aplicación de diversas estrategias requiere la acción concertada de diferentes instituciones y sectores gubernamentales, así como de miembros activos de las comunidades, educadores, extensionistas, grupos de riesgo y sus familias, etc.


Iron deficiency is the most common nutritional deficiency worldwide. In Mexico, in 2006, 37.8% of children under 2 years of age were diagnosed as anemic. Similarly, 20% of children between 2-5 years of age, as well as 16.6% of children between 5-11 years of age were diagnosed with anemia. Children 1-4 years of age consuming a Mexican diet ingest an adequate amount of iron (≈ 6.2 mg/day), but the intake of heme-iron is low, and ingestión of iron absorption inhibitors is high; thus, the overall iron bioavailability in the diet is poor (3.85%). Strategies to prevent and treat iron deficiency and anemia may be focused on either increasing the amount of ingested iron or lowering iron losses; whereas in the newborn, delayed umbilical cord clamping is advised. These strategies require a comprehensive and concerted aproach among institutions, governmental sectors, community active members, educators, risk groups, families, etc.

14.
J Hum Lact ; 24(1): 50-7, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18281356

ABSTRACT

In a cross-sectional study, 163 breastfeeding women completed the Edinburgh Postnatal Depression Scale (EPDS), a questionnaire on demographics and infant feeding and hand-expressed breast milk for Na and K quantification, between 2 and 12 weeks postpartum. Forty women (24.5%) had an EPDS score compatible with the risk of a depressive episode, and 63 (41%) did not feel confident about breastfeeding. These 2 variables were significantly correlated to each other and individually correlated to breastfeeding exclusiveness. Weeks postpartum was correlated to breastfeeding exclusiveness and Na:K in milk (all P < .001). A logistic regression model showed that supplementation increased the risk of high Na:K in milk by 209%, whereas a longer time postpartum lowered the risk for mammary gland permeability. This study suggests that postpartum depression and low breastfeeding confidence, which may be present concomitantly, are associated with increased mammary gland permeability, only to the extent in which depression dissuades the mother from exclusive breastfeeding.


Subject(s)
Breast Feeding/epidemiology , Breast Feeding/psychology , Depression, Postpartum/epidemiology , Mammary Glands, Human/physiology , Adolescent , Adult , Cross-Sectional Studies , Depression, Postpartum/psychology , Female , Humans , Infant , Infant, Newborn , Lactation , Logistic Models , Male , Mammary Glands, Human/metabolism , Mastitis/epidemiology , Mastitis/etiology , Milk, Human/chemistry , Potassium/analysis , Risk Factors , Sodium/analysis
15.
Food Nutr Bull ; 29(4): 334-9, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19227058

ABSTRACT

OBJECTIVE: To develop a reference pattern to evaluate gestational weight according to pregestational body mass index (BMI) and gestational age, using current longitudinal information from healthy pregnant women. SUBJECTS AND METHODS: We followed 438 women with singleton pregnancies between weeks 16 and 36 of pregnancy Women were excluded if they developed pathologic conditions during gestation, delivered malformed or dead fetuses, or delivered babies with a birthweight of less than 2500 or more than 4200 g or with a gestational age of less than 37 or more than 41 weeks. Weight, biochemical indicators, and clinical indicators were recorded every 4 weeks throughout the pregnancy. Data were analyzed by sequential regressions. RESULTS: Four equations for maternal predicted weight across categories of pregestational BMI (underweight, normal, overweight, and obese) and gestational ages were developed and synthesized in a table of reference values. CONCLUSIONS: Optimal weight and weight gain during pregnancy can be estimated with our equations, which are corrected for pregestational BMI and gestational age.


Subject(s)
Body Mass Index , Gestational Age , Weight Gain/physiology , Adolescent , Adult , Birth Weight/physiology , Body Height/physiology , Body Weight/physiology , Child , Female , Humans , Infant, Newborn , Mexico , Predictive Value of Tests , Pregnancy , Reference Values , Young Adult
16.
J Am Coll Nutr ; 26(2): 156-62, 2007 Apr.
Article in English | MEDLINE | ID: mdl-17536127

ABSTRACT

OBJECTIVE: To evaluate the energy, nutrient intakes and dietary patterns of Mexican lactating women at one month postpartum, and the associations of maternal age and region on their intakes. METHODS: A total of 60 women were studied: 41 from Northwest and 19 from Central Mexico, 33 adolescent and 27 adult women. Data were collected through two quantitative 24 h recalls. Two more recalls were used in a sub sample to calculate the coefficient of variation of intakes. Menus were based on the consumption frequency of foods. RESULTS: The mean energy intake of the adolescent women (2354 +/- 1199 kcal) and those of Central Mexico (1690 +/- 981 kcal) was lower than the recommendations. Zinc, calcium, vitamin E, C and folate were inadequate (55 to 85% prevalence of inadequacy). Energy, dietary fiber, sodium, potassium, iron and folate intakes were higher (P < 0.05) in Northwest Mexico. Northwestern women consumed less variety of vegetables or fruits compared to Mexico City region women. Wheat tortillas and beans were from Northwestern but not from the Mexico City region diet. CONCLUSIONS: The energy and nutrient intakes of women were different by regional hospital and not by age. Education about the importance of the maternal diet during lactation should be directed toward increasing consumption of foods rich in micronutrients.


Subject(s)
Energy Intake/physiology , Feeding Behavior , Health Promotion , Lactation/physiology , Micronutrients/administration & dosage , Nutritional Requirements , Adolescent , Adult , Dietary Fiber/administration & dosage , Female , Fruit , Humans , Maternal Age , Mental Recall , Mexico , Nutrition Policy , Nutritive Value , Vegetables
17.
Food Nutr Bull ; 28(2): 198-205, 2007 Jun.
Article in English | MEDLINE | ID: mdl-24683679

ABSTRACT

BACKGROUND: Lime-treated corn gruel (atole) is a common weaning food in iron-deficient populations, especially in Mexico and Central America, and is a potential vehicle for fortification with iron. OBJECTIVE: The objective of this study was to screen promising iron compounds for use in the fortification of atole, using in vitro enzymatic digestion-dialysis techniques, while also considering their response to known iron absorption enhancers and inhibitors. METHODS: Atole, unaltered or preincubated with phytase, was fortified with iron (10 mg/L) from ferrous sulfate, ferrous bisglycinate, or ferrous fumarate, or with ferric chloride, ferric ammonium citrate, or ferric sodium ethylenediaminetetraacetic acid (NaFeEDTA), and submitted to in vitro digestion. Dialysis of calcium, copper, iron, phosphorus, and zinc (analyzed by inductively coupled plasma atomic emission spectrometry) was measured when atole was fortified with iron compounds alone or together with ascorbic acid or disodium ethylenediaminetetraacetic acid (Na2EDTA). RESULTS: Iron dialyzability was higher with NaFeEDTA (p < .05) than with all other iron compounds, which did not differ among themselves in iron dialyzability. Addition of ascorbic acid had no significant effect on iron dialysis, whereas Na2EDTA enhanced iron dialyzability by 7 to 10 times in unaltered atole and 15 to 20 times in phytase-preincubated atole (p < .05). Addition of Na2EDTA always increased intrinsic zinc dialyzability, and most of the time this increase was significant. Phytase pretreatment generally increased mineral dialysis. CONCLUSIONS: Adding EDTA (either as NaFeEDTA or as Na2EDTA) to atole can increase the dialyzability of ferrous and ferric iron compounds and enhance the dialyzability of intrinsic zinc without any negative effects on calcium, phosphorus, or copper dialysis.


Subject(s)
Ascorbic Acid/pharmacology , Edetic Acid/pharmacology , Iron, Dietary/administration & dosage , Minerals/metabolism , Phytic Acid/pharmacokinetics , Zea mays/chemistry , 6-Phytase/metabolism , Biological Availability , Central America , Dialysis , Ferric Compounds/metabolism , Ferrous Compounds/metabolism , Food, Fortified , Humans , In Vitro Techniques , Iron, Dietary/pharmacokinetics , Mexico , Minerals/analysis , Pancreatin/metabolism , Pepsin A/metabolism
18.
J Nutr ; 136(10): 2498-501, 2006 Oct.
Article in English | MEDLINE | ID: mdl-16988116

ABSTRACT

Maternal energy requirements increase during pregnancy but the magnitude of this increment is unknown among adolescents. We determined the effects of maternal age and weight status on adjustments in gestational weight gain, resting energy expenditure (REE), and growth among adolescents. Weight, and growth rates of pregnant adolescents (PA) < or =17 y during late pregnancy were compared with changes in nonpregnant adolescents (NPA) over a 5-mo period. REE was also measured monthly in the PA group. Paired t-tests and general linear models for repeated measures were used for the analysis; height was included as a confounding variable. Weight, height, and BMI of the PA and NPA women did not differ at baseline. During the follow-up period, NPA grew 0.94 +/- 30 cm; growth rate was greater in adolescents < or =14 y of age (P < 0.001) than in the older subjects. No growth occurred in the PA group. REE tended to increase linearly between 20 and 36 wk of gestation (P = 0.164); the net change in women >14 y (25%) tended (P = 0.164) to be greater than that of younger adolescents (7%). The mean increment of REE from wk 20 to wk 36 was 230 +/- 30 kcal/d (962 +/- 126 kJ/d) and the smallest increase occurred in women with BMI <20 (P = 0.010). Women with BMI <20 had a decrease in REE/kg that was greater than that of normal weight (BMI 20-25) or overweight (BMI > or =25) women (within subject, P = 0.010; between subject, P = 0.001). In conclusion, PA appear to adjust their resting energy needs by ceasing growth.


Subject(s)
Birth Weight , Energy Metabolism , Growth , Pregnancy in Adolescence/physiology , Adolescent , Body Height , Body Mass Index , Body Weight , Female , Humans , Infant, Newborn , Pregnancy , Weight Gain
19.
Perinatol. reprod. hum ; 20(1/3): 19-26, ene.-sep. 2006. ilus, tab
Article in Spanish | LILACS | ID: lil-632285

ABSTRACT

Objetivo: Determinar el efecto de la nutrición materna sobre el crecimiento fetal en gestaciones múltiples con resultado perinatal adecuado. Material y métodos: Se realizó un estudio de cohorte con gestantes de 20 semanas de embarazo, sin patología agregada. Mensualmente se evaluó peso, fondo uterino (FU) y gasto energético en reposo (GER). Para el análisis de los cambios en peso, FU y GER se utilizó la prueba de ANOVA para datos repetidos, las diferencias intrasujetos fueron con base en la edad gestacional y las diferencias intersujetos en función al tipo de embarazo e IMC pregestacional (IMCp). Resultados: La muestra estuvo constituida por 39 gestantes (19 EM y 20 EU). Se tomaron los eventos exitosos (10 EM como casos y 11 EU como controles). El peso corporal incrementó significativamente entre la semana 0-32 y existió una interacción tiempo de gestación e IMCp (p < 0.05). El FU mostró un incremento significativo a lo largo de la gestación (p < 0.001), que fue dependiente del tipo de embarazo (p < 0.001) y no se vio afectado por el IMCp (p > 0.05). El GER mostró un incremento lineal significativo (p < 0.05), que fue independiente del tipo de gestación (p > 0.05), pero dependiente del IMCp (p < 0.05). Cuando se analizó el GER/kg de peso, se encontró un menor gasto/kg en las mujeres con sobrepeso (p < 0.05). Conclusiones: Los determinantes de la nutrición materna de la semana 20 y hasta la semana 32 de gestación, dependen del IMCp y no del tipo de embarazo; a diferencia del de crecimiento fetal que depende del tipo de embarazo.


Objetive: To determine the effect of maternal nutritional status on fetal growth in twin pregnancies with good perinatal outcome. Material y methods: A cohort conformed by 39 healthy pregnant women with 20 weeks of gestation or less(19 with twin pregnancy (TP)and 20 with singleton pregnancy (SP)). Every four weeks height, weight, uterine fundus height (UFH)and resting energy expenditure (REE) were measured. General Lineal Models for repeated measures were used to evaluate longitudinal changes in body weight, REE, and UFH at 20, 24, 28, and 32 weeks of pregnancy (within subjects) The group was divided by pregnancy type or BMI (< 25, and > 25) (between subjects) in order to evaluate their effect on weight, uterine fundus height and REE changes. Results: The successful deliveries were uses for the analysis (10TP as cases and 11 SP as controls). Weight gain increased significantly between 0 and 32 weeks of gestation with an interaction between gestational age and prepregnancy body mass index (pBMI) (p < 0.05). The UFH also increased significantly during gestation (p < 0.001); this increase was dependant on pregnancy type (p < 0.001) and it was not affected by the pBMI (p > 0.05). REE showed a linear increase (p < 0.05) that depended on the pBMI (p < 0.05) but not on pregnancy type (p > 0.05). When the REE/kg was analyzed, the weight showed a lower energy expenditure per kg in overweight women (p < 0.05). Conclusions: Maternal nutritional determining factors from 20 to 32 weeks of gestation depends on the pBMI and did not depend on pregnancy type, while fetal growth did.

20.
Arch Med Res ; 37(5): 674-82, 2006 Jul.
Article in English | MEDLINE | ID: mdl-16740440

ABSTRACT

BACKGROUND: We undertook this study to compare the effectiveness and safety of antenatal daily and weekly supplementation with iron, folic acid, and vitamin B(12) in healthy, pregnant women who were not anemic at gestational week 20. METHODS: Women with singleton pregnancies and blood hemoglobin (Hb) >115 g/L at gestational week 20 (equivalent to 105 g/L at sea level) were randomly assigned to two groups, one consuming one tablet containing 60 mg iron, 200 mug folic acid and 1 mug vitamin B(12) daily (DS, n = 56); the other consuming two tablets once weekly (WS, n = 60). Blood Hb and serum ferritin concentrations were measured every 4 weeks from weeks 20 to 36, and pregnancy outcomes were evaluated. RESULTS: Mild anemia and hypoferritinemia throughout pregnancy occurred less frequently in DS than WS. None of the 116 women had Hb concentrations <103 g/L at any evaluation point. In contrast, hemoconcentration (Hb >145 g/L) from gestational week 28 onwards occurred in 11% in DS and 2% in WS. We observed ex post facto that hemoconcentration at gestational week 28 was associated with a significantly higher relative risk of low birth weight (RR 6.23, 95% CI 1.46-26.57) and premature delivery (RR 7.78, 95% CI 1.45-24.74). CONCLUSIONS: In women who were nonanemic at gestational week 20, both schemes (DS and WS) prevented the occurrence of Hb levels <100 g/L. DS women had a higher incidence of hemoconcentration. Hemoconcentration was associated with increased risk of low birth weight and premature delivery.


Subject(s)
Dietary Supplements , Iron/administration & dosage , Pregnancy , Adult , Anemia/blood , Anemia/prevention & control , Dietary Supplements/adverse effects , Drug-Related Side Effects and Adverse Reactions , Female , Ferritins/blood , Folic Acid/administration & dosage , Folic Acid/adverse effects , Gestational Age , Hematinics/administration & dosage , Hematinics/adverse effects , Hemoglobins/analysis , Humans , Infant, Low Birth Weight/blood , Infant, Newborn , Iron/adverse effects , Pregnancy/blood , Pregnancy Complications, Hematologic/blood , Pregnancy Complications, Hematologic/prevention & control , Premature Birth/blood , Premature Birth/prevention & control , Risk Factors , Vitamin B 12/administration & dosage , Vitamin B 12/adverse effects , Vitamin B Complex/administration & dosage , Vitamin B Complex/adverse effects
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