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Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil.
Cunha, Marcela S; Cruz, Nádia V G; Schnellrath, Laila C; Medaglia, Maria Luiza Gomes; Casotto, Michele E; Albano, Rodolpho M; Costa, Luciana J; Damaso, Clarissa R.
Emerg Infect Dis ; 23(10): 1737-1739, 2017 10.
Article in English | MEDLINE | ID: mdl-28930027

ABSTRACT

We isolated East/Central/South African genotype chikungunya virus during the 2016 epidemic in Rio de Janeiro, Brazil. Genome sequencing revealed unique mutations in the nonstructural protein 4 (NSP4-A481D) and envelope protein 1 (E1-K211T). Moreover, all Brazil East/Central/South isolates shared the exclusive mutations E1-M407L and E2-A103T.


Subject(s)
Aedes/virology , Chikungunya Fever/epidemiology , Chikungunya Fever/transmission , Chikungunya virus/genetics , Insect Vectors/virology , RNA, Viral/genetics , Adolescent , Adult , Africa/epidemiology , Animals , Brazil/epidemiology , Chikungunya Fever/virology , Chikungunya virus/classification , Chikungunya virus/isolation & purification , Chlorocebus aethiops , Female , Genotype , Humans , Male , Phylogeny , Vero Cells
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