Prevention of relapse in the recovery of Arizona health care providers.

This project gathered survey information from physicians, physician assistants, dentists and pharmacists in Arizona who, while enrolled or following a completion of a monitored aftercare program, had relapsed back to active chemical dependency. The findings suggest several subjective factors that contributed to the subjects' relapse included (1) dishonesty to self, (2) not working a 12 step program, and (3) denial of the problem. Factors reported to be helpful for future relapse prevention were (1) abstinence from substance use, (2) working a 12 step program, and (3) having spiritual beliefs. In general, survey respondents were male, averaged 52 years of age, had relapsed several times and started abusing illicit drugs and alcohol in high school or college. By identifying the specific causes of relapse, future studies may attempt to decrease the percentage of health care providers who relapse by recognizing signs of problematic behavior before they occur.

Three-year retrospective review of superficial radiotherapy for skin conditions in a Perth radiotherapy unit.

Western Australia has only two superficial radiotherapy units, one of which is located at Fremantle Hospital, and run by the radiation oncologists of Perth Radiation Oncology Centre. A 3-year retrospective review was undertaken of all patients who underwent treatment at this unit from 1999 to 2001. Patients were identified from the unit's log book, and data was collected from their files. For malignant skin conditions, 369 lesions were treated in 259 patients over the study period. The patients' median age was 76 years. A wide variety of conditions were treated, but the most common diagnoses were basal cell carcinoma (237 lesions) and squamous cell carcinoma (92 lesions), most commonly located in the head region. The most frequently used treatment schedule was 36 Gy in six fractions over a 3-week period. Where radiotherapy was administered as primary treatment, the diagnoses had been biopsy-proven in only 53% of cases. Fifty-four patients underwent treatment of benign skin disease over the study period; most commonly keloid scars (41 patients) followed by warts (six patients). We conclude that superficial radiotherapy has a distinct role in dermatology, particularly for skin carcinomas around the nose and eyes, which cannot presently be superseded by electron beam therapy.

Use of adjuvant, preoperative chemo-radiotherapy in patients with locally advanced rectal cancer.

BACKGROUND: The objective of this study was to perform a non-randomised prospective examination of the efficacy of adjuvant, preoperative chemo-radiotherapy in patients with locally advanced rectal cancer. METHODS: Between 1996 and 2001, patients presenting with biopsy-proven, locally advanced, rectal cancers within 12 cm of the anal verge were referred for a long course of adjuvant chemo-radiotherapy prior to their surgery. Locally advanced lesions were defined by either: (i) endoanal ultrasound showing at least full thickness penetration of the rectal wall (i.e. T3, T4); (ii) abdominal computed tomography scan showing infiltration of adjacent structures, or; (iii) clinical examination demonstrating a fixed lesion. All patients were followed through the hospital colorectal unit. A Kaplan-Meier survival analysis was used to determine survival and local recurrence rates. RESULTS: There were 60 patients with a mean age of 61.5 years (range 33-77 years) with a sex distribution of males to females of 1.7-1.0. Curative resections were performed in 81% of these patients. The remainder (n = 12) were found to have either metastatic disease at operation (n = 5), inoperable disease (n = 2), or had positive resection margins on histology (n = 7). The mean follow up was 2.1 years (maximum 5.1 years). The overall 2-year survival rate was 86.1% (95% CI +/-5.4%). In patients undergoing curative resections, the overall 2-year survival rate was 91.4% (95% CI +/-4.8%), and the 2-year disease free survival rate was 85.1% (95% CI +/-6.2%). The 2-year local recurrence rate was 7.5%. CONCLUSIONS: The use of adjuvant, preoperative, chemo-radiotherapy in patients with locally advanced rectal cancer is associated with high short-term survival and a low recurrence rate.