ABSTRACT
The development of a cancer of the esophagus in women who previously had received radiotherapy for breast cancer is a known although infrequent event. The risk of apparition of the second neoplasia is greater in women who survive at least ten years after the exposition to the radiation. Squamous cell carcinoma is the histological subtype more frequent. We report a case of adenocarcinoma of the esophagus in a man diagnosed of benign symmetrical lipomatosis (Madelung' disease), who had received adjuvant radiotherapy three years before for breast cancer.
Subject(s)
Adenocarcinoma/complications , Breast Neoplasms, Male/complications , Carcinoma, Ductal, Breast/complications , Esophageal Neoplasms/complications , Lipomatosis, Multiple Symmetrical/complications , Neoplasms, Radiation-Induced/etiology , Neoplasms, Second Primary/etiology , Radiotherapy, Adjuvant/adverse effects , Aged , Alcohol Drinking/adverse effects , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Barrett Esophagus/complications , Breast Neoplasms, Male/drug therapy , Breast Neoplasms, Male/radiotherapy , Breast Neoplasms, Male/surgery , Carcinoma, Ductal, Breast/drug therapy , Carcinoma, Ductal, Breast/radiotherapy , Carcinoma, Ductal, Breast/surgery , Chemotherapy, Adjuvant , Combined Modality Therapy , Deglutition Disorders/etiology , Fatal Outcome , Hematemesis/etiology , Humans , Lymph Node Excision , Male , Mastectomy, Modified Radical , Risk Factors , Smoking/adverse effectsABSTRACT
La aparición de un cáncer de esófago en mujeres que previamente han recibido radioterapia como tratamiento de un cáncer de mama es un hecho conocido aunque poco frecuente. El riesgo de aparición de la segunda neoplasia es mayor cuando han transcurrido diez o más años desde la exposición a la radiación. La estirpe histológica de la neoplasia de esófago más frecuente es la de carcinoma de células escamosas. Se presenta un caso de adenocarcinoma de esófago en un varón, diagnosticado de lipomatosis bilateral simétrica o enfermedad de Madelung, que recibió radioterapia tres años antes por presentar un cáncer de mama
The development of a cancer of the esophagus in women who previously had received radiotherapy for breast cancer is a known although infrequent event. The risk of apparition of the second neoplasia is greater in women who survive at least ten years after the exposition to the radiation. Squamous cell carcinoma is the histological subtype more frequent. We report a case of adenocarcinoma of the esophagus in a man diagnosed of benign symmetrical lipomatosis (Madelung disease), who had received adjuvant radiotherapy three years before for breast cancer
Subject(s)
Male , Aged , Humans , Adenocarcinoma/complications , Carcinoma, Ductal, Breast/complications , Lipomatosis, Multiple Symmetrical/complications , Radiotherapy, Adjuvant/adverse effects , Breast Neoplasms, Male/complications , Neoplasms, Radiation-Induced/etiology , Alcohol Drinking/adverse effects , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Barrett Esophagus/complications , Carcinoma, Ductal, Breast/drug therapy , Carcinoma, Ductal, Breast , Carcinoma, Ductal, Breast/surgery , Chemotherapy, Adjuvant , Deglutition Disorders/etiology , Fatal Outcome , Lymph Node Excision , Risk Factors , Breast Neoplasms, Male/drug therapy , Breast Neoplasms, Male , Breast Neoplasms, Male/surgeryABSTRACT
Primary leiomyosarcoma of the liver is a rare entity and fewer than 100 cases have been reported in the medical literature. Even more unusual is the association with another previous tumour. We report the case of a 84-year-old man who had been treated for a gastric non-Hodgkin lymphoma two years previously. He presented with a painful mass in the right upper abdomen. An ultrasound scan showed a large mass in the right lobe of the liver and chest radiography showed pulmonary metastases. Liver biopsy was performed and immunohistochemical analysis revealed a malignant leiomyosarcoma. We discuss this case and review the available literature.
Subject(s)
Leiomyosarcoma/secondary , Liver Neoplasms/pathology , Lung Neoplasms/secondary , Lymphoma, Non-Hodgkin/pathology , Neoplasms, Multiple Primary/pathology , Stomach Neoplasms/pathology , Aged , Aged, 80 and over , Female , Humans , Leiomyosarcoma/diagnosis , Liver Neoplasms/diagnosis , Lung Neoplasms/diagnosis , Lymphoma, Non-Hodgkin/therapy , Male , Neoplasms, Multiple Primary/diagnosis , Stomach Neoplasms/therapySubject(s)
Heart Failure/etiology , Hypoparathyroidism/complications , Aged , Female , Humans , Hypocalcemia/complicationsABSTRACT
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