ABSTRACT
El coriocarcinoma es un tumor epitelial altamente maligno, constituido exclusivamente por elementos trofoblásticos con ausencia de vellosidades coriónicas e invasión del miometrio. Forma parte de la enfermedad trofoblástica gestacional maligna y se caracteriza por producir elevados niveles sanguíneos de hormona gonadotrofina coriónica. Su frecuencia es de uno por cada 50.000 gestaciones. El coriocarcinoma puede surgir de cualquier tejido trofoblástico: embarazo molar (50%), aborto (25%), embarazo ectópico (2,5%) y gestación normal (22,5%). Hemos de presentar un caso que nos surgió en la consulta de urgencias en obstetricia, que durante el puerperio fue diagnosticada de coriocarcinoma
Choriocarcinoma is a highly malignant epithelial tumour consisting exclusively of trophoblastic elements without chorionic villi and myometrial invasion. It is part of malignant gestational trophoblastic disease and is characterised by elevated blood levels of the hormone chorionic gonadotropin. Its prevalence is 1 in 50,000 pregnancies. Choriocarcinoma may arise from any trophoblastic tissue: molar pregnancy (50%), abortion (25%), ectopic pregnancy (2.5%) or normal pregnancy (22.5%). We present a case of choriocarcinoma diagnosed during the puerperium by the obstetrics emergency department
Subject(s)
Humans , Female , Adult , Pregnancy , Choriocarcinoma/diagnosis , Postpartum Period , Gestational Trophoblastic Disease/complications , Gestational Trophoblastic Disease/diagnosis , Myometrium/pathology , Postpartum Hemorrhage/drug therapy , Chorionic Gonadotropin/therapeutic use , Emergency Medical Services/methods , Risk Factors , Postpartum Period/physiologyABSTRACT
Osteoblastoma is an infrequent primary osseous tumour. Its presentation in the upper extremities and more specifically in the carpal bones is unusual. We present a case of osteoblastoma localized in the hamate bone and review the treatment realized in this infrequent localization. A young male patient with pain and swelling in the back of his hand of one year's evolution, resistant to medical treatment. Complementary tests showed lytic tumefaction in the hamate bone with non-aggressive characteristics. It was treated by curettage and filling the iliac crest with autologous graft. The pathological anatomical study diagnosed that it was a case of osteoblastoma. The result was satisfactory, with total disappearance of the pain and a radiological image of complete restitution of the osseous defect, with no signs of recurrence after 4 years. The treatment should be curettage plus autologous graft. Conversely, resection of the affected bone can be considered in cases with aggressive data.
Subject(s)
Bone Neoplasms , Hamate Bone , Osteoblastoma , Adult , Bone Neoplasms/diagnosis , Bone Neoplasms/surgery , Humans , Male , Osteoblastoma/diagnosis , Osteoblastoma/surgeryABSTRACT
El osteoblastoma es un tumor óseo primario poco frecuente. Su presentación en la extremidad superior y más específicamente en los huesos carpianos es inusual. Se presenta un caso de osteoblastoma localizado en el hueso ganchoso y ser revisa el tratamiento realizado en esta infrecuente localización. Paciente varón joven con dolor y tumefacción en el dorso de la mano de un año de evolución, refractario al tratamiento médico. Las pruebas complementarias mostraron una tumoración lítica en el hueso ganchoso con características no agresivas. Fue tratado mediante curetaje y relleno con injerto autólogo de cresta ilíaca. El estudio de anatomía patológica diagnosticó que se trataba de un osteoblastoma. El resultado fue satisfactorio, con desaparición total del dolor e imagen radiológica de restitución completa del defecto óseo, sin signos de recidiva a los 4 años. El tratamiento debe ser el curetaje más injerto autólogo. En cambio, en los casos con datos agresivos se puede plantear la resección del hueso afectado (AU)
Osteoblastoma is an infrequent primary osseous tumour. Its presentation in the upper extremities and more specifically in the carpal bones is unusual. We present a case of osteoblastoma localized in the hamate bone and review the treatment realized in this infrequent localization. A young male patient with pain and swelling in the back of his hand of one year's evolution, resistant to medical treatment. Complementary tests showed lytic tumefaction in the hamate bone with non-aggressive characteristics. It was treated by curettage and filling the iliac crest with autologous graft. The pathological anatomical study diagnosed that it was a case of osteoblastoma. The result was satisfactory, with total disappearance of the pain and a radiological image of complete restitution of the osseous defect, with no signs of recurrence after 4 years. The treatment should be curettage plus autologous graft. Conversely, resection of the affected bone can be considered in cases with aggressive data (AU)
Subject(s)
Humans , Male , Adult , Osteoblastoma/complications , Osteoblastoma/surgery , Osteoblastoma , Hamate Bone/physiopathology , Hamate Bone/surgery , Hamate Bone , Radionuclide Imaging , Gated Blood-Pool Imaging , Magnetic Resonance Imaging/methodsABSTRACT
BACKGROUND: Humeral nonunion that persists through various unsuccessful attempts at management, presents a real challenge. When combined with severe osteoporosis in elderly patients, the problems only increase. This study aims to investigate the best option for treating this combination of factors. MATERIALS AND METHOD: This study analyses the outcomes of five patients with the following inclusion criteria: nonunion of the humeral diaphysis, after at least two unsuccessful interventions and/or after a period of 18 months or more, associated with severe osteoporosis in patients aged over 65. All cases were treated by debridement of the site of nonunion and stabilisation with locking plates and bone graft. RESULTS: All cases consolidated after a mean follow-up period of 19 months (8-36 months). CONCLUSIONS: In cases of humeral nonunion in elderly patients with osteoporotic bones, locking plates have been proven to provide consistent, long-term stability, with better results than traditional compression plates. The authors consider that locking plates should be considered as a valid option in cases of extreme bone and biological instability, as is the case in recalcitrant humeral nonunion.
Subject(s)
Humeral Fractures/surgery , Pseudarthrosis/surgery , Aged , Female , Humans , Humeral Fractures/complications , Osteoporosis/complications , Pseudarthrosis/complicationsABSTRACT
Fundamento: La pseudoartrosis de húmero, cuando varios intentos previos para su curación ya han fracasado, es un reto. Si asociamos la osteoporosis severa propia de pacientes ancianos, las dificultades se multiplican. El objetivo es estudiar la mejor opción para esta situación. Material y método: Analizamos la evolución de cinco pacientes con los siguientes criterios de inclusión: pseudoartrosis de la diáfisis del húmero intervenida sin éxito previamente al menos en dos ocasiones y/o haber permanecido en dicha situación más de 18 meses, asociado a osteoporosis severa en personas mayores de 65 años. Fueron tratados mediante desbridamiento del foco y estabilización con placas bloqueadas asociando injerto óseo. Resultados: Todos los casos consolidaron tras un seguimiento medio de 19 meses (8-36 meses). Conclusiones: En la pseudoartrosis de húmero en ancianos con hueso osteoporótico, las placas bloqueadas han demostrado que proporcionan una fijación estable y duradera, superior a la de las placas tradicionales a compresión. En nuestra experiencia hay que considerarlas también como una opción válida en situaciones de máxima precariedad ósea y biológica, como sucede en las pseudoartrosis recalcitrantes(AU)
Background: Humeral nonunion that persists through various unsuccessful attempts at management, presents a real challenge. When combined with severe osteoporosis in elderly patients, the problems only increase. This study aims to investigate the best option for treating this combination of factors. Materials and method: This study analyses the outcomes of five patients with the following inclusion criteria: nonunion of the humeral diaphysis, after at least two unsuccessful interventions and/or after a period of 18 months or more, associated with severe osteoporosis in patients aged over 65. All cases were treated by debridement of the site of nonunion and stabilisation with locking plates and bone graft. Results: All cases consolidated after a mean follow-up period of 19 months (8-36 months). Conclusions: In cases of humeral nonunion in elderly patients with osteoporotic bones, locking plates have been proven to provide consistent, long-term stability, with better results than traditional compression plates. The authors consider that locking plates should be considered as a valid option in cases of extreme bone and biological instability, as is the case in recalcitrant humeral nonunion (AU)
