Aneurismas de las arterias pulmonares en relación al síndrome de Hughes Stovin / Aenurysms of the pulmonary arteries in relation to Hughes Stovin syndrome

El síndrome de Hughes Stovin es una vasculitis de pequeños y grandes vasos, más frecuente en hombres jóvenes. Se manifiesta con trombosis y aneurismas. Inicia con tromboflebitis que evoluciona a aneurismas con eventual desenlace fatal por ruptura de los mismos. Algunos autores consideran el síndrome de Hughes Stovin como una variante de la enfermedad de Behçet. El diagnóstico es clínico y el tratamiento de primera línea son los corticoides y la ciclofosfamida. Frente a un caso de trombosis, la anticoagulación es controversial por el riesgo de sangrado. Presentamos el caso de un varón joven con cuadro clínico compatible en el cual se descartaron otras patologías con requerimiento de tratamiento quirúrgico por mala evolución clínica.

Hughes Stovin syndrome is characterized by small and big vessels vasculitis, more commonly presented in young men. Initially it manifests with thrombophlebitis and aneurysms which can cause fatal bleed due to rupture. Some authors consider Hughes Stovin syndrome as a variant of Behcet's disease. Diagnosis is made by clinical findings and the first line treatment are corticosteroids and cyclophosphamide. Anticoagulation is controversial due to the increased risk of hemorrhage.

Determination of trace metals in Mytilus galloprovincialis along the Boka Kotorska Bay, Montenegrin coast.

The concentrations of six trace metals, cadmium (Cd), copper (Cu), chromium (Cr), lead (Pb), zinc (Zn) and mercury (Hg) were determined in the soft tissues of the mussel Mytilus galloprovincialis and bottom sediments collected from the coastal area of Boka Kotorska Bay (Montenegrin coast). The mussels and sediment samples were collected at three sites along the Boka Kotorska Bay from the autumn of 2014 to the winter of 2016. The concentrations (mg/kg dw) of these metals in the mussel samples ranged from 1.01 to 2.87 for Cd, 6.08 to 13.2 for Cu, 1.37 to 3.55 for Pb, 85.6 to 241 for Zn, 0.72 to 4.05 for Cr and 0.098 to 0.269 for Hg. The concentrations (mg/kg dw) of these metals in the sediment samples ranged from 0.16 to 0.39 for Cd, 4.32 to 48.2 for Cu, 7.02 to 49.8 for Pb, 22.0 to 158 for Zn, 93.1 to 317 for Cr and 0.035 to 0.497 for Hg. The metal content in the mussel samples and the metal content in the sediment collected from three locations over four different seasons were analyzed using the Pearson correlation coefficient (r) and cluster analysis (CA). A correlation between the metal levels found in the mussel soft tissues with those found in the sediments, for both 2014 and 2015, were established. The metal pollution indexes (MPI) for the sediment and mussels were compared, indicating that the most polluted sediment was at the location Institute of Marine Biology Kotor (IBMK) and the most polluted mussels were sampled from the Zanjice location.

O controle da raiva: eficácia do treino cognitivo na doença arterial coronariana / Anger control: the effectiveness of cognitive anger control training in coronary artery disease

Este estudo teve por objetivos averiguar se o treino cognitivo de controle da raiva é eficaz na redução da reatividade cardiovascular de pacientes diagnosticados com doença arterial coronariana, avaliar seu impacto na redução da raiva e no nível de stress e analisar se há correlação significativa entre a raiva e a magnitude na reatividade cardiovascular em momentos de stress experimental. Vinte e nove adultos com doença arterial coronariana participaram da pesquisa. A reatividade cardiovascular foi aferida, antes e após o tratamento em grupo para a raiva, em sessões de role-play representando situações de stress interpessoal. Resultados mostraram que o tratamento reduziu significativamente os índices de raiva para dentro, raiva estado, raiva traço, expressão, reação e controle da raiva e sintomatologia do stress. A magnitude da reatividade da pressão arterial sistólica correlacionou-se com os índices de raiva temperamento. Verificou-se uma redução significativa na reatividade da pressão arterial sistólica na terceira avaliação, realizada seis meses após o treino cognitivo de controle da raiva.(AU)

The objectives of this study were twofold: to test the effectiveness of Cognitive Anger Control Training in the reduction of cardiovascular reactivity during periods of stress in individuals with coronary artery disease, and to investigate the link between levels of anger and the extent of cardiovascular reactivity at times of stress. Twenty-nine adults suffering from coronary artery disease took part in the study. Cardiovascular reactivity was measured both before and after group treatment for anger, in role-play sessions representing situations of interpersonal stress. The findings show that the treatment significantly reduced the indices of internal anger, state anger, trait anger, the expression, reaction and control of anger and level of stress. It was also found that systolic blood pressure reactivity had a significant correlation with the indices of temperamental anger and that a significant reduction was seen in systolic blood pressure reactivity in the third evaluation, conducted six months after treatment.(AU)

O controle da raiva: eficácia do treino cognitivo na doença arterial coronariana / Anger control: the effectiveness of cognitive anger control training in coronary artery disease

Este estudo teve por objetivos averiguar se o treino cognitivo de controle da raiva é eficaz na redução da reatividade cardiovascular de pacientes diagnosticados com doença arterial coronariana, avaliar seu impacto na redução da raiva e no nível de stress e analisar se há correlação significativa entre a raiva e a magnitude na reatividade cardiovascular em momentos de stress experimental. Vinte e nove adultos com doença arterial coronariana participaram da pesquisa. A reatividade cardiovascular foi aferida, antes e após o tratamento em grupo para a raiva, em sessões de role-play representando situações de stress interpessoal. Resultados mostraram que o tratamento reduziu significativamente os índices de raiva para dentro, raiva estado, raiva traço, expressão, reação e controle da raiva e sintomatologia do stress. A magnitude da reatividade da pressão arterial sistólica correlacionou-se com os índices de raiva temperamento. Verificou-se uma redução significativa na reatividade da pressão arterial sistólica na terceira avaliação, realizada seis meses após o treino cognitivo de controle da raiva.

The objectives of this study were twofold: to test the effectiveness of Cognitive Anger Control Training in the reduction of cardiovascular reactivity during periods of stress in individuals with coronary artery disease, and to investigate the link between levels of anger and the extent of cardiovascular reactivity at times of stress. Twenty-nine adults suffering from coronary artery disease took part in the study. Cardiovascular reactivity was measured both before and after group treatment for anger, in role-play sessions representing situations of interpersonal stress. The findings show that the treatment significantly reduced the indices of internal anger, state anger, trait anger, the expression, reaction and control of anger and level of stress. It was also found that systolic blood pressure reactivity had a significant correlation with the indices of temperamental anger and that a significant reduction was seen in systolic blood pressure reactivity in the third evaluation, conducted six months after treatment.