ABSTRACT
INTRODUCTION: Postobstructive diuresis (POD) is a polyuric state in which large quantities of salt and water are eliminated after solving a urinary tract obstruction. These patients are at increased risk of severe dehydration, electrolytic disturbances, hypovolemic shock, and death. Ureteropelvic junction obstruction (UPJO) is the most common etiology of collecting system dilatation in the fetal kidney, and a significant number of patients require pyeloplasty. There are limited data regarding prognostic risk factors for POD in this scenario. OBJECTIVE: To describe possible clinical risk factors for POD in the pediatric population after open pyeloplasty. STUDY DESIGN: This was a retrospective case series study of consecutive patients diagnosed with UPJO at three high complexity centers, managed with open pyeloplasty from 2006 to 2016. Multiple qualitative and quantitative variables possibly associated with POD were included according to the literature review. They were statistically analyzed with STATA 14 software. RESULTS: A total of 88 patients with UPJO following open pyeloplasty were analyzed. Twenty-seven patients (30%) had POD. A tendency to present POD in younger patients was found, with a mean age of 20.2 months vs. 72.3 months. There was also an increased risk of POD in patients with previous diagnosis of tubular acidosis. CONCLUSIONS: There are no data about prognostic clinical risk factors for POD after open pyeloplasty in the pediatric population. Our study corresponds to one of the larger series reported so far. It suggests that younger patients and patients with a previous diagnosis of tubular acidosis could be at greater risk of POD. Consequently, prospective studies are required for validation of our results, and possible impact on patient follow-up.
Subject(s)
Diuresis/physiology , Kidney Pelvis/surgery , Plastic Surgery Procedures/methods , Ureter/surgery , Ureteral Obstruction/surgery , Urologic Surgical Procedures/methods , Child , Child, Preschool , Female , Follow-Up Studies , Humans , Infant , Infant, Newborn , Laparoscopy , Male , Retrospective Studies , Ureteral Obstruction/physiopathologyABSTRACT
La incidencia de la enfermedad litiásica ha aumentado globalmente en los últimos 25 años. A pesar de que la incidencia de litiasis es baja en la población pediátrica,1 ese aumento no ha sido ajeno a esa población. Se ha visto un incremento importante en su incidencia y prevalencia en los últimos años, alcanzado en países como Estados Unidos de 18,5 por cada 100.000 habitantes.2 La edad de presentación se encuentra entre los 7 y los 8 años de edad.
The incidence of lithium disease has increased globally over the past 25 years. Although the incidence of lithiasis is low in the paediatric population,1 this increase has not been alien to the paediatric population. There has been a significant increase in its incidence and prevalence in recent years, reached in countries such as the United States of 18.5 per 100,000 inhabitants.2 The age of presentation is between 7 and 8 years of age
