ABSTRACT
Caso clínico: El Complejo de Carney (CNC) es un raro síndrome multineoplásico, autosómico dominante; caracterizado por presentar mixomas, lesiones pigmentadas en la piel, tumores endocrinos y manifestaciones oculares. Discusión: Analizamos los signos oftalmológicos de este síndrome, los cuales suelen preceder al componente más serio del mismo, el mixoma cardíaco
Case report: Carney complex (CNC) is a multiple neoplasia syndrome, inherited in an autosomal dominant manner, characterized by myxomas, spotty skin pigmentation, endocrine tumors and ophthalmic abnormalities. Discussion: We report the ocular findings which usually precede the most serious component of the complex, the cardiac myxoma
Subject(s)
Female , Adult , Humans , Myxoma/pathology , Neoplastic Syndromes, Hereditary/pathology , Papilloma/pathology , Eyelid Neoplasms/pathology , Heart Neoplasms/pathology , Skin Neoplasms/pathology , Conjunctival Diseases/genetics , Conjunctival Diseases/pathology , Lentigo/genetics , Lentigo/pathology , Myxoma/genetics , Neoplastic Syndromes, Hereditary/diagnosis , Neoplastic Syndromes, Hereditary/genetics , Papilloma/genetics , Eyelid Neoplasms/genetics , Heart Neoplasms/genetics , Skin Neoplasms/geneticsABSTRACT
CASE REPORT: Carney complex (CNC) is a multiple neoplasia syndrome, inherited in an autosomal dominant manner, characterized by myxomas, spotty skin pigmentation, endocrine tumors and ophthalmic abnormalities. DISCUSSION: We report the ocular findings which usually precede the most serious component of the complex, the cardiac myxoma.
Subject(s)
Eyelid Neoplasms/pathology , Heart Neoplasms/pathology , Myxoma/pathology , Neoplastic Syndromes, Hereditary/pathology , Papilloma/pathology , Skin Neoplasms/pathology , Adult , Conjunctival Diseases/genetics , Conjunctival Diseases/pathology , Eyelid Neoplasms/genetics , Female , Heart Neoplasms/genetics , Humans , Lentigo/genetics , Lentigo/pathology , Myxoma/genetics , Neoplastic Syndromes, Hereditary/diagnosis , Neoplastic Syndromes, Hereditary/genetics , Papilloma/genetics , Skin Neoplasms/geneticsABSTRACT
A postoperative increase in the pulmonary extravascular fluid volume (PEFV) and a disturbance of pulmonary gas exchange are regularly observed in patients undergoing cardiac surgery. These alterations, due to a reduction in the colloidal osmotic pressure (COP) increase the morbidity and mortality when crystalloid solutions are infused. This study was based on 90 patients infused with 1,500 cc of crystalloid solution without albumin. The COP, total proteins, albumin and globulin were determined in the plasma preoperatively, during bypass and immediately postoperatively, in order to define a formula allowing calculation of the COP from the plasma proteins to avoid reaching dangerously high figures. The authors concluded that there is a direct correlation between COP and total proteins (total proteins = 1.36 + 0.24 COP) and a potential curve with an adjustment point between COP and albumin (albumin = 0.23 COP0.93). Determination of the COP from globulins is not recommended. The authors elaborated two normograms for everyday clinical use. These formulae allow the calculation of COP in children, elderly subjects and patients in a critical condition, thereby avoiding dangerous levels of COP during infusion of crystalloid solutions.
Subject(s)
Blood Proteins/analysis , Cardiopulmonary Bypass , Osmotic Pressure , Serum Albumin/analysis , Adolescent , Adult , Alpha-Globulins/analysis , Beta-Globulins/analysis , Child , Female , Heart Diseases/surgery , Humans , Male , Middle Aged , gamma-Globulins/analysisSubject(s)
Echocardiography , Foreign Bodies/diagnosis , Foreign-Body Migration/diagnosis , Heart Valve Prosthesis , Adult , Humans , Male , Mitral Valve , Prosthesis FailureABSTRACT
A new technique of circular tricuspid annuloplasty in the treatment of tricuspid insufficiency is described. One hundred and fifty patients have been operated on by this technique between April 1973 and March 1975. The operative findings and the results of the operation from 6 to 30 months after operation are described. The addition of tricuspid circular annuloplasty to mitral and aortic valve replacements where indicated has resulted in a gratifying fall in operative mortality and better long term functional result.
