ABSTRACT
It is unclear how rising obesity among people with HIV (PWH) in sub-Saharan Africa (SSA) impacts their risk of type 2 diabetes mellitus (diabetes). Using a South African national cross-sectional sample of adult PWH and their peers without HIV (PWOH), we examined the associations between HIV and prevalent diabetes across the spectrum of body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WtHR). Analyses were sex stratified, and adjusted for age, sociodemographic and behavioral factors. The prevalence of diabetes among males was similar between PWH and PWOH, overall and at all levels of adiposity. In contrast, overall diabetes prevalence was higher among female PWOH than female PWH. However, there were differences according to adiposity such that, compared to female PWOH, relative diabetes prevalence in female PWH was reduced with obesity but accentuated with leanness. These differences in the relationship between adiposity and diabetes by HIV serostatus call for better mechanistic understanding of sex-specific adipose tissue biology in HIV in South Africa, and possibly in other HIV endemic settings in SSA.
ABSTRACT
The cognitive effects of LOGO were examined among 11-12-year-old black and white Zimbabwean girls and boys. Fifty-two experimental group children were exposed to a BBC LOGO programme with a screen turtle. Forty-one control group children received no exposure to computers at school. Pre-tests on four WISC-R subscales were held in January, 1987 and post-tests on the same four WISC-R subscales were held in November/December, 1987. The data were analyzed with multivariate analysis of covariance, using pre-test scores as the covariate. The results suggested that children in the experimental group did better on the WISC-R Arithmetic scale and that black girls exposed to LOGO showed particular gains in spatial reasoning, as measured by the WISC-R Block Design scale. It is concluded that LOGO appears to facilitate cognitive growth. Methodological limitations of the present study are discussed and suggestions for future resea3cli are presented.
