Prevalence of Excess Sodium Intake and Their Corresponding Food Sources in Adults from the 2017-2018 Brazilian National Dietary Survey.

Excessive sodium intake has been related to high blood pressure, a central risk factor for cardiovascular disease. In the present work, updated estimates of sodium intake, the main food sources, and the prevalence of excessive intakes in a nationwide multi-ethnic sample of Brazilian adults (2017-2018 Brazilian National Dietary Survey) were presented. Based on two 24-h recalls adjusted for the within-person variation, the overall median of sodium intake was 2432 mg. The prevalence of adults exceeding the recommended limits (tolerable upper limit, UL, and the chronic disease risk reduction cut-off point, CDRR) was 61% and 56%, respectively. The median sodium intake and proportion of individuals above the limits varied according to the subgroups evaluated. Males and adults (20-29 years) presented the highest excessive sodium intakes, and consequently, lowest adherence rates to UL and CDRR recommendations. The top food sources of sodium were white bread and toast (12.3%), beans (11.6%), white rice (10.6%), beef (7.7%), and poultry meat (5.5%). Given the health benefits of dietary sodium reduction, it would be advisable to enhance the current national initiatives of awareness and educational campaigns' combined efforts to reduce sodium in processed foods to effectively decrease this micronutrient intake across the Brazilian population.

Food Insecurity Reduces the Chance of Following a Nutrient-Dense Dietary Pattern by Brazilian Adults: Insights from a Nationwide Cross-Sectional Survey.

Dietary patterns derived by data-driven techniques are still scarce in the food security context and may be a useful tool to inform policymakers to promote adequate and healthy diets for vulnerable populations. We investigated the association between food security status and dietary patterns among 28,127 Brazilian adults using data from the 2017-2018 Household Budget Survey. Food security status was measured by the Brazilian Food Insecurity Scale. Food items reported in two 24 h dietary recalls were combined into food groups. Dietary patterns were derived from exploratory factor analysis, and participants were grouped according to their factor scores by K-means cluster analysis. Multiple logistic regression models were fitted to investigate the association between food security status and clusters of adherence to dietary patterns. Four dietary patterns were derived: 'Brazilian breakfast style' (cluster 3), 'Brazilian Traditional staple foods' (cluster 2), 'Beverages, ready-to-eat and convenience foods' (cluster 4), and 'Fruits, vegetables, and whole grains' (cluster 1). After adjustments, food insecurity was inversely associated with adherence to the 'Fruits vegetables, and whole grains' pattern (OR = 0.75, 95% CI: 0.63-0.89). Findings suggest food insecurity negatively impact the adoption of a nutrient-dense dietary pattern and highlight the critical role of policy actions in a scenario of increasing food insecurity.

A chrononutrition perspective of diet quality and eating behaviors of Brazilian adolescents in associated with sleep duration.

It is well recognized that sleep and food intake exhibit 24-h patterns and disturbances of these patterns can lead to health problems. Cross-sectional and prospective studies suggest that diet quality and eating behaviors are negatively affected by short sleep duration. Adolescence is a particularly vulnerable period for the emergence of inadequate sleep and diet patterns. The aim of the study was to investigate associations, from a chrononutrition perspective, of diet quality, nutrients intake, and eating behaviors (eating frequency, eating period, and time-interval between eating occasions) in relation to sleep duration among a multi-ethnic cohort of Brazilian adolescents. Data were collected by the 2015 ISA-Capital survey, a population-based cross-sectional study comprising 419 adolescents of both sexes (12-19 years old) of São Paulo, Brazil. Demographic, socioeconomic, anthropometric, and lifestyle, including sleep duration, data were obtained from an interviewer-administered structured questionnaire. Dietary data were obtained by 24-h dietary recall (24-HDR), and diet quality was assessed by the Brazilian Healthy Eating Index - Revised (BHEI-R), validated for the Brazilian population. The independent associations between sleep duration categories (i.e., <8 h as short sleep and 8-10 h as adequate sleep), and dietary variables were assessed after adjustments for covariates. Multiple linear, logistic, and Poison regression models were used, depending on the variable. Diet quality, nutrients intake, and eating behaviors differed according to adolescents' sleep duration. Approximately 36% of adolescents were sleep deprived. They presented poorer diet quality (53 points, p = .034) and eating behaviors characterized by lower probability of having lunch (88%, p < .001) and dinner (71%, p < .001) and higher probabilities of eating breakfast (87%, p < .001) and morning snack (26%, p = .001). These adolescents compared to those with adequate sleep duration also had, from snacks and in the 24-h cycle, higher contribution of available carbohydrates (8%, p < .001; 50%, p = .024) and total sugar (6%, p < .001; 21%, p < .001) and added sugar (3%, p < .001; 15%, p < .001). The chrononutrition characteristics of sleep-deprived adolescents were marked by longer eating periods (12 h, p < .001) and time-interval between eating occasions (3 h, p < .001) than adolescents with adequate sleep duration. These differences point to the relevance of the interrelation between sleep and diet, i.e., disruption of circadian cycles and consequent metabolic health problems, to inform public health policies and clinical interventions.

Nutritional breakfast quality and cardiometabolic risk factors: Health Survey of São Paulo, a population-based study.

OBJECTIVE: To evaluate the association between nutritional quality of breakfast and cardiometabolic risk factors. DESIGN: Cross-sectional study, 2015 Health Survey of São Paulo (2015 ISA-Capital) with Focus on Nutrition Study (2015 ISA-Nutrition). SETTINGS: Population-based study, with a representative sample of adults and elderlies living in São Paulo, Brazil. PARTICIPANTS: The sample included 606 adults (aged 20-59 years) and 537 elderlies (aged ≥60 years) from the 2015 Health Survey of São Paulo. Dietary intake was assessed by at least one 24-h recall. Breakfast quality was evaluated using the proposed Brazilian Breakfast Quality Index (BQI), ranging scores from 0 to 10. BQI associations with sociodemographic, lifestyle, dietetic and cardiometabolic variables were estimated using survey-weighted multiple logistic regression models. RESULTS: Being ≥60 years of age, self-identifying as White or Asian, having a per capita family income with ≥1 minimum wage, being sufficiently active at leisure time and non-smoker were associated with better scores of BQI. A higher BQI score was inversely associated with elevated blood pressure (OR 0·81, 95 % CI 0·70, 0·94), fasting glucose (OR 0·85, 95 % CI 0·73, 0·98), HOMA-IR (OR 0·86, 95 % CI 0·74, 0·98), total cholesterol (OR 0·87, 95 % CI 0·76, 0·99), LDL-C (OR 0·85, 95 % CI 0·74, 0·97), metabolic syndrome (OR 0·82, 95 % CI 0·72, 0·93) and being overweight (OR 0·87, 95 % CI 0·76, 0·99). CONCLUSIONS: Breakfast quality of Brazilian adults needs improvement with disparities across some sociodemographic factors. BQI was associated with lower odds of cardiometabolic risk factors, suggesting a beneficial effect in this population and emphasising the role of breakfast in reducing the risk of CVD.

Principal Component Analysis and Factor Analysis: differences and similarities in Nutritional Epidemiology application.

INTRODUCTION: Statistical methods such as Principal Component Analysis (PCA) and Factor Analysis (FA) are increasingly popular in Nutritional Epidemiology studies. However, misunderstandings regarding the choice and application of these methods have been observed. OBJECTIVES: This study aims to compare and present the main differences and similarities between FA and PCA, focusing on their applicability to nutritional studies. METHODS: PCA and FA were applied on a matrix of 34 variables expressing the mean food intake of 1,102 individuals from a population-based study. RESULTS: Two factors were extracted and, together, they explained 57.66% of the common variance of food group variables, while five components were extracted, explaining 26.25% of the total variance of food group variables. Among the main differences of these two methods are: normality assumption, matrices of variance-covariance/correlation and its explained variance, factorial scores, and associated error. The similarities are: both analyses are used for data reduction, the sample size usually needs to be big, correlated data, and they are based on matrices of variance-covariance. CONCLUSION: PCA and FA should not be treated as equal statistical methods, given that the theoretical rationale and assumptions for using these methods as well as the interpretation of results are different.

Eating behaviours and dietary intake associations with self-reported sleep duration of free-living Brazilian adults.

Sleep duration in modern societies has been decreasing over the past decades and many environmental and behaviour factors contribute with. Evidence have shown that individuals with short sleep duration have worse eating behaviours and dietary intakes than those with adequate sleep. This study aimed to describe eating behaviours and dietary intakes of Brazilian adults and investigate their associations with self-reported sleep duration encompassing aspects of chrono-nutrition. Demographic, socioeconomic, anthropometric, lifestyle, sleep duration and dietary data were obtained from an interviewer-administered structured questionnaire of the cross-sectional population-based study, 2015 ISA-Capital, (n = 1081 adults, ≥20y). The independent associations between sleep duration (categories: ≤6 h, 7-8 h, and ≥9 h) and dietary variables were assessed after adjustment for covariates. Employment status, physical activity, number of chronic diseases and day of recalled intake were significantly associated with sleep duration categories (p < 0.05). Short duration sleepers (≤6 h) showed the largest probabilities of eating breakfast and snacks. Snacks contributed to 23% of total energy intake and provided the largest amounts of total and added sugar than other eating occasions among short duration sleepers. Long duration sleepers (≥9 h) exhibited lower probability of consumption of the three main meals, lower energy and nutrient intakes in the morning, lower eating frequency and shorter eating period. Irrespective of sleep duration, the largest contribution to total energy intake was in the afternoon (43-46%), followed by the evening (30-32%) and morning (22-25%) periods. In conclusion, sleep duration was associated with different dietary intakes and eating behaviours among Brazilian adults. The largest energy intakes in the afternoon and evening periods signalize the relevance to consider the timing of food consumption aside sleep duration as a target to nutritional counseling for prevention of circadian misalignment and related metabolic disturbances.

Principal Component Analysis and Factor Analysis: differences and similarities in Nutritional Epidemiology application / Análise de Componentes Principais e Análise Fatorial: diferenças e similaridades na aplicação em Epidemiologia Nutricional

ABSTRACT: Introduction: Statistical methods such as Principal Component Analysis (PCA) and Factor Analysis (FA) are increasingly popular in Nutritional Epidemiology studies. However, misunderstandings regarding the choice and application of these methods have been observed. Objectives: This study aims to compare and present the main differences and similarities between FA and PCA, focusing on their applicability to nutritional studies. Methods: PCA and FA were applied on a matrix of 34 variables expressing the mean food intake of 1,102 individuals from a population-based study. Results: Two factors were extracted and, together, they explained 57.66% of the common variance of food group variables, while five components were extracted, explaining 26.25% of the total variance of food group variables. Among the main differences of these two methods are: normality assumption, matrices of variance-covariance/correlation and its explained variance, factorial scores, and associated error. The similarities are: both analyses are used for data reduction, the sample size usually needs to be big, correlated data, and they are based on matrices of variance-covariance. Conclusion: PCA and FA should not be treated as equal statistical methods, given that the theoretical rationale and assumptions for using these methods as well as the interpretation of results are different.

RESUMO: Introdução: Métodos estatísticos de análise multivariada, tais como Análise de Componentes Principais e Análise Fatorial, têm sido cada vez mais utilizados nos estudos em Epidemiologia Nutricional, no entanto equívocos quanto à escolha e aplicação dos métodos são observados. Objetivos: Os objetivos deste estudo são comparar e apresentar as principais diferenças e similaridades conceituais e metodológicas entre Análise de Componentes Principais e Análise Fatorial visando à aplicabilidade nos estudos em nutrição. Métodos: Análise de Componentes Principais e Análise Fatorial foram aplicadas em uma matriz de 34 grupos de alimentos que expressaram o consumo alimentar médio de 1.102 indivíduos de um estudo populacional. Resultados: Um total de dois fatores foi extraído e juntos explicaram 57,66% da variância comum entre as variáveis dos grupos alimentares, enquanto um total de cinco componentes foi extraído e juntos explicaram 26,25% da variância total. Entre as principais diferenças envolvendo os dois métodos estão: pressuposto de normalidade; as matrizes de variância-covariância/correlação, com consequente quantidade de variância explicada; a carga fatorial/componente e o erro associado. Entre as similaridades estão: ambas as técnicas são usadas para redução de dados; necessitam de um grande tamanho de amostra; os dados precisam ser correlacionados e são baseadas nas matrizes de variância-covariância/correlação. Conclusão: Análise de Componentes Principais e Análise Fatorial não devem ser tratadas como métodos estatísticos iguais e intercambiáveis, uma vez que o racional teórico e os pressupostos para o uso dos métodos, assim como a interpretação dos resultados, são diferentes.

Validation of self-reported diabetes in a representative sample of São Paulo city.

OBJECTIVE To validate the self-reported diabetes mellitus in adults and older adults living in the city of São Paulo, Brazil. METHODS We have used data of 569 subjects (284 adults and 285 older adults), participants of the population-based cross-sectional study Inquérito de Saúde do Município de São Paulo (Health Survey of São Paulo). Fasting glucose ≥ 7.0 mmol/L (126 mg/dL) and/or use of drugs (oral hypoglycemic and/or insulin) defined the diagnosis of diabetes mellitus. We have validated the self-reported diabetes mellitus by calculating the sensitivity, specificity, positive predictive values, and negative predictive values. We have used Poisson regression with robust variance to verify the factors associated with the sensitivity of the self-reported datum. For all analyses, we have considered the sample design of the study. RESULTS The sensitivity of self-reported diabetes mellitus was 63.8% (95%CI 49.2-76.3), specificity was 99.7% (95%CI 99.1-99.9), positive predictive value was 95.5% (95%CI 84.4-98.8), and negative predictive value was 96.9% (95%CI 94.9-98.2). The correct reporting of diabetes mellitus was more prevalent among older adults (PR = 2.0; 95%CI 1.2-3.5) than among adults. CONCLUSIONS The use of the datum of self-reported diabetes mellitus is valid, especially among older adults living in the city of São Paulo. The results highlight the need to track diabetes mellitus in asymptomatic subjects who have one or more risk factors for it, mainly in the adult population of this city.

Dairy products consumption in Brazil is associated with socioeconomic and demographic factors: Results from the National Dietary Survey 2008-2009 / Consumo de lácteos e derivados no Brasil está associado com fatores socioeconômicos e demográficos: resultados do Inquérito Nacional de Alimentação 2008-2009

ABSTRACT Objective: To estimate the consumption of dairy products in the Brazilian population. Methods: Data from two non-consecutive food records from 34,003 individuals (aged ³10 years) in the first Brazilian nationally representative dietary survey (2008-2009) were used to estimate the dairy products intake. Dairy products were divided into four major subgroups: cow's milk, cheese, yogurt and other dairy products. Absolute and relative frequencies of individuals in the population who reported consumption of dairy products in at least one of the two-day food record according to sex, age, geographic region and levels of per capita monthly family income were calculated. Moreover, the mean consumption of dairy products, as well as their nutritional contribution in total energy, protein, calcium, phosphorus and magnesium intake was estimated. Results: It was observed that only 43.0% of the population reported consuming dairy products, being the milk subgroup the most frequently consumed (21.1%). The prevalence of consumption was higher among females, elderly, residents of the South region, and among individuals from higher per capita monthly family income. The nutritional contribution of dairy products was less than 10.0% of total energy intake and for most nutrients and the mean daily consumption are justified was 101.8g. Conclusion: Therefore, in view of the low intake of dairy products by Brazilian population and the nutritional benefits associated with this food group, public health strategies to increase dairy consumption are justified.

RESUMO Objetivo: Estimar o consumo de produtos lácteos pela população brasileira. Métodos: Dados de consumo alimentar obtidos por meio de registro alimentar de dois dias não-consecutivos de 34.003 indivíduos com 10 anos ou mais de idade participantes do Primeiro Inquérito Nacional de Alimentação (2008-2009) foram utilizados para estimar o consumo de produtos lácteos. Os produtos lácteos foram divididos em quatro subgrupos maiores: leite, queijo, iogurte e outros lácteos. Frequências absolutas e relativas de indivíduos da população que reportaram consumir os produtos lácteos em pelo menos um dos registros alimentares foram calculadas conforme sexo, idade, região geográfica e níveis de renda familiar mensal per capita. Além disso, estimou-se a quantidade média de consumo dos produtos lácteos, assim como sua contribuição para a ingestão de energia total, proteína, cálcio, fósforo e magnésio. Resultados: Observou-se que apenas 43,0% da população consome produtos lácteos, sendo o leite o produto mais frequentemente consumido (21,1%). A prevalência de consumo foi superior entre o sexo feminino, os idosos e os indivíduos residentes na região Sul e pertencentes aos maiores estratos de renda familiar per capita. A contribuição nutricional dos produtos lácteos para a ingestão de energia e para a maioria dos nutrientes avaliados foi inferior a 10,0% e seu consumo médio diário foi de 101.8g. Conclusão: Tendo em vista o baixo consumo de produtos lácteos pela população brasileira e os benefícios associados a este grupo de alimentos, justificam-se estratégias de saúde pública para o aumento do consumo deste grupo de alimentos.

Nutritional quality of dietary patterns of children: are there differences inside and outside school? / Qualidade nutricional dos padrões alimentares de crianças: existem diferenças dentro e fora da escola?

Abstract: Objectives: To describe the dietary patterns of children inside and outside school and investigate their associations with sociodemographic factors and nutritional status. Methods: This was a multicenter cross-sectional study in which children of both sexes, aged 1-6 years, attending private and public daycare centers and preschools in Brazil, were evaluated (n = 2979). Demographic, socioeconomic and dietary data (weighed food records and estimated food records) were collected. Dietary patterns were derived by factor analysis from 36 food groups. Results: Four dietary patterns were identified inside school, and three outside. Inside school, the "traditional" pattern was associated to low income and presented high nutritional quality. The "dual" pattern was associated with low income and with high intake of added sugar and glycemic load. The "snack" pattern was associated with children enrolled at private schools and with high intake of added sugar and glycemic load. The "bread and butter" pattern was associated with high intake of added sugar and trans fat. Outside school, the "traditional" pattern was associated with high intake of saturated fat, trans fats, sodium, and total fiber. The "bread and butter" pattern was associated with high intake of trans fats and glycemic load, whereas the "snack" pattern was associated with overweight, private schools, high income, and high intake of trans fats, sodium, and total fiber. Conclusion: There are differences in the nutritional quality of dietary patterns inside and outside school, and heterogeneity in adherence to these patterns were observed across regions and socioeconomic classes.

Resumo: Objetivos: Descrever os padrões alimentares de crianças dentro e fora da escola e investigar a sua associação com fatores sociodemográficos e estado nutricional. Métodos: Estudo multicêntrico transversal, no qual foram avaliadas crianças de 1 a 6 anos de ambos os sexos, atendidas em creches públicas e privadas e pré-escolas no Brasil (n = 2.979). Foram coletados dados demográficos, socioeconômicos e dietéticos. Os padrões alimentares foram derivados por análise fatorial a partir de 36 grupos de alimentos. Resultados: Quatro padrões alimentares foram identificados dentro e três fora da creche. Dentro da creche, o padrão "tradicional" foi associado a menor renda e apresentou melhor qualidade nutricional. O padrão "dual" associou-se a menor renda e maior ingestão de açúcar de adição e carga glicêmica. O padrão "lanches" foi associado a crianças matriculadas em escolas privadas e com maior ingestão de açúcar de adição e carga glicêmica. O padrão "pão com manteiga" associou-se a maior ingestão de açúcar de adição e gordura trans. Fora da creche, o padrão "tradicional" foi associado a maior ingestão de gordura saturada, trans, sódio e fibra. O padrão "pão com manteiga" associou-se a maior ingestão de gordura trans e carga glicêmica, enquanto o padrão "lanches" associou-se às crianças com excesso de peso, de creches privadas, maior renda e com maior ingestão de gordura trans, sódio e fibra. Conclusão: Houve diferença na qualidade nutricional dos padrões dentro e fora da escola e a adesão a esses ocorreu de forma heterogênea nas regiões e classes socioeconômicas.

Nutritional quality of dietary patterns of children: are there differences inside and outside school?

OBJECTIVES: To describe the dietary patterns of children inside and outside school and investigate their associations with sociodemographic factors and nutritional status. METHODS: This was a multicenter cross-sectional study in which children of both sexes, aged 1-6 years, attending private and public daycare centers and preschools in Brazil, were evaluated (n=2979). Demographic, socioeconomic and dietary data (weighed food records and estimated food records) were collected. Dietary patterns were derived by factor analysis from 36 food groups. RESULTS: Four dietary patterns were identified inside school, and three outside. Inside school, the "traditional" pattern was associated to low income and presented high nutritional quality. The "dual" pattern was associated with low income and with high intake of added sugar and glycemic load. The "snack" pattern was associated with children enrolled at private schools and with high intake of added sugar and glycemic load. The "bread and butter" pattern was associated with high intake of added sugar and trans fat. Outside school, the "traditional" pattern was associated with high intake of saturated fat, trans fats, sodium, and total fiber. The "bread and butter" pattern was associated with high intake of trans fats and glycemic load, whereas the "snack" pattern was associated with overweight, private schools, high income, and high intake of trans fats, sodium, and total fiber. CONCLUSION: There are differences in the nutritional quality of dietary patterns inside and outside school, and heterogeneity in adherence to these patterns were observed across regions and socioeconomic classes.

Proposal for a breakfast quality index for brazilian population: Rationale and application in the Brazilian National Dietary Survey.

Breakfast has been related to positive nutrition and health outcomes, but criteria for an optimal composition of this meal are not well established. The aim of this study was to propose a breakfast quality index (BQI) for the Brazilian population, and to describe the relationship between breakfast quality, socio-demographic factors, dietary intake at breakfast and for the total day. BQI was constructed based on individual dietary data of 22,279 breakfast consumers, aged 20+ years from the Brazilian National Dietary Survey, a population-based cross-sectional study. The BQI was comprised of food components (cereals, fruit/vegetables, dairy products), and nutrient criteria (energy, fiber, free sugar, saturated fat, calcium and sodium). Mean, percentage and 95% CIs were estimated for variables according to BQI categories. The mean BQI was 4.2, with 71% of individuals falling into medium BQI category and 6% in high category. Individuals in urban areas, in higher categories of income and education and women had higher BQI means. Consumers with high BQI had higher intake of fruits/vegetables and higher breakfast and total daily intake of energy, carbohydrates, fiber, total sugar, sodium, potassium, phosphorus, thiamin, riboflavin, niacin, folate and vitamins B6, A, C, and D, and lower trans fatty acids compared to those in low and medium BQI groups. Promoting a high-quality breakfast may contribute to a better nutrient intake and achievement of daily requirements.

Validation of self-reported diabetes in a representative sample of São Paulo city

ABSTRACT OBJECTIVE To validate the self-reported diabetes mellitus in adults and older adults living in the city of São Paulo, Brazil. METHODS We have used data of 569 subjects (284 adults and 285 older adults), participants of the population-based cross-sectional study Inquérito de Saúde do Município de São Paulo (Health Survey of São Paulo). Fasting glucose ≥ 7.0 mmol/L (126 mg/dL) and/or use of drugs (oral hypoglycemic and/or insulin) defined the diagnosis of diabetes mellitus. We have validated the self-reported diabetes mellitus by calculating the sensitivity, specificity, positive predictive values, and negative predictive values. We have used Poisson regression with robust variance to verify the factors associated with the sensitivity of the self-reported datum. For all analyses, we have considered the sample design of the study. RESULTS The sensitivity of self-reported diabetes mellitus was 63.8% (95%CI 49.2–76.3), specificity was 99.7% (95%CI 99.1–99.9), positive predictive value was 95.5% (95%CI 84.4–98.8), and negative predictive value was 96.9% (95%CI 94.9–98.2). The correct reporting of diabetes mellitus was more prevalent among older adults (PR = 2.0; 95%CI 1.2–3.5) than among adults. CONCLUSIONS The use of the datum of self-reported diabetes mellitus is valid, especially among older adults living in the city of São Paulo. The results highlight the need to track diabetes mellitus in asymptomatic subjects who have one or more risk factors for it, mainly in the adult population of this city.

Examining associations between dietary patterns and metabolic CVD risk factors: a novel use of structural equation modelling.

The association between dietary patterns and metabolic cardiovascular risk factors has long been addressed but there is a lack of evidence towards the effects of the overall diet on the complex net of biological inter-relationships between risk factors. This study aimed to derive dietary patterns and examine their associations with metabolic cardiovascular risk factors following a theoretic model for the relationship between them. Participants included 417 adults of both sexes, enrolled to the cross-sectional population-based study performed in Brazil. Body weight, waist circumference, high-sensitivity C-reactive protein, blood pressure, total cholesterol:HDL-cholesterol ratio, TAG:HDL-cholesterol ratio, fasting plasma glucose and serum leptin were evaluated. Food consumption was assessed by two non-consecutive 24-h dietary recalls adjusted for the within-person variation of intake. A total of three dietary patterns were derived by exploratory structural equation modelling: 'Traditional', 'Prudent' and 'Modern'. The 'Traditional' pattern had a negative and direct effect on obesity indicators (serum LEP, body weight and waist circumference) and negative indirect effects on total cholesterol:HDL-cholesterol ratio, TAG:HDL-cholesterol ratio and fasting plasma glucose. The 'Prudent' pattern had a negative and direct effect on systolic blood pressure. No association was observed for the 'Modern' pattern and metabolic risk factors. In conclusion, the 'Traditional' and 'Prudent' dietary patterns were negatively associated with metabolic cardiovascular risk factors among Brazilian adults. Their apparent protective effects against obesity and high blood pressure may be important non-pharmacological strategies for the prevention and control of obesity-related metabolic disorders and CVD.

Probability and amounts of yogurt intake are differently affected by sociodemographic, economic, and lifestyle factors in adults and the elderly-results from a population-based study.

The aim of this population-based cross-sectional health survey (N = 532) was to investigate the factors associated with the probability and amounts of yogurt intake in Brazilian adults and the elderly. A structured questionnaire was used to obtain data on demographics, socioeconomic information, presence of morbidities and lifestyle and anthropometric characteristics. Food intake was evaluated using two nonconsecutive 24-hour dietary recalls and a Food Frequency Questionnaire. Approximately 60% of the subjects were classified as yogurt consumers. In the logistic regression model, yogurt intake was associated with smoking (odds ratio [OR], 1.98), female sex (OR, 2.12), and age 20 to 39 years (OR, 3.11). Per capita family income and being a nonsmoker were factors positively associated with the amount of yogurt consumption (coefficients, 0.61 and 3.73, respectively), whereas the level of education of the head of household was inversely associated (coefficient, 0.61). In this study, probability and amounts of yogurt intake are differently affected by demographic, socioeconomic, and lifestyle factors in adults and the elderly.

Empirically derived dietary patterns: interpretability and construct validity according to different factor rotation methods.

This study aimed to investigate the effects of factor rotation methods on interpretability and construct validity of dietary patterns derived in a representative sample of 1,102 Brazilian adults. Dietary patterns were derived from exploratory factor analysis. Orthogonal (varimax) and oblique rotations (promax, direct oblimin) were applied. Confirmatory factor analysis assessed construct validity of the dietary patterns derived according to two factor loading cut-offs (≥ |0.20| and ≥ |0.25|). Goodness-of-fit indexes assessed the model fit. Differences in composition and in interpretability of the first pattern were observed between varimax and promax/oblimin at cut-off ≥ |0.20|. At cut-off ≥ |0.25|, these differences were no longer observed. None of the patterns derived at cut-off ≥ |0.20| showed acceptable model fit. At cut-off ≥ |0.25|, the promax rotation produced the best model fit. The effects of factor rotation on dietary patterns differed according to the factor loading cut-off used in exploratory factor analysis.

Sex differences in serum leptin and its relation to markers of cardiometabolic risk in middle-aged adults: evidence from a population-based study.

OBJECTIVE: At elevated concentrations, circulating leptin has been associated with metabolic disturbances, namely insulin resistance, elevated blood pressure, inflammation, and endothelial dysfunction. Because women have higher leptin concentrations than men, it is possible that the effects of leptin on the metabolic profile are different between the sexes. The aim of this study was to investigate whether leptin is one of the key hormones to sex affect differences in the pathophysiology of cardiometabolic risk. METHODS: Participants were 178 men and 284 women (average age: 53.9 y), evaluated in a cross-sectional, population-based study performed in Brazil. A structural equation model was used to test a theoretic pathway for the relationship between serum leptin, obesity indicators (body weight and waist circumference), and cardiometabolic risk factors (high-sensitivity C-reactive protein; blood pressure; atherogenic dyslipidemia-total cholesterol/high-density lipoprotein cholesterol (HDL-C) ratio and triacylglycerol /HDL-C ratio; and fasting plasma glucose) stratified by sex. RESULTS: In men, increasing 1 SD in serum leptin predicted an increase in 0.731 SD in body weight and in 0.123 SD in C-reactive protein. Serum leptin had positive and significant indirect effects on men's ratios of total cholesterol to HDL-C (ß = 0.215) and triacylglycerol to HDL-C (ß = 0.209), as well as fasting glucose (ß = 0.173). In women, serum leptin predicted an increase of 0.675 SD in body weight and had positive indirect effects on all cardiometabolic risk factors evaluated. CONCLUSIONS: Serum leptin was indirectly related to cardiometabolic risk factors and its relation was modest and different between sexes. The effects of leptin through mediation of body weight and waist circumference highlight the importance of weight control to prevent cardiometabolic disorders in middle-aged adults.

Empirically derived dietary patterns: interpretability and construct validity according to different factor rotation methods / Padrões alimentares empiricamente derivados: interpretabilidade e validade de construto segundo diferentes métodos de rotação fatorial / Patrones alimentarios empíricamente derivados: interpretabilidad y validez de constructo, según diferentes métodos de rotación en un análisis factorial

This study aimed to investigate the effects of factor rotation methods on interpretability and construct validity of dietary patterns derived in a representative sample of 1,102 Brazilian adults. Dietary patterns were derived from exploratory factor analysis. Orthogonal (varimax) and oblique rotations (promax, direct oblimin) were applied. Confirmatory factor analysis assessed construct validity of the dietary patterns derived according to two factor loading cut-offs (≥ -0.20- and ≥ -0.25-). Goodness-of-fit indexes assessed the model fit. Differences in composition and in interpretability of the first pattern were observed between varimax and promax/oblimin at cut-off ≥ -0.20-. At cut-off ≥ -0.25-, these differences were no longer observed. None of the patterns derived at cut-off ≥ -0.20- showed acceptable model fit. At cut-off ≥ -0.25-, the promax rotation produced the best model fit. The effects of factor rotation on dietary patterns differed according to the factor loading cut-off used in exploratory factor analysis.

Objetivou-se investigar os efeitos dos métodos de rotação fatorial na interpretabilidade e validade de construto de padrões alimentares em uma amostra representativa de 1.102 adultos brasileiros. Os padrões foram derivados por análise fatorial exploratória. As rotações ortogonal (varimax) e oblíqua (promax e oblimin direta) foram utilizadas. Avaliou-se a validade de construto dos padrões segundo os pontos de corte de cargas fatoriais: (≥ -0,20- e ≥ -0,25-) por meio de análise fatorial confirmatória. Índices de qualidade de ajuste do modelo foram analisados. Observaram-se diferenças na composição e interpretabilidade do primeiro padrão obtido pelas rotações varimax e promax/oblimin no ponto de corte ≥ -0,20-. No ponto de corte ≥ -0,25-, não foram observadas diferenças. Nenhum dos padrões derivados no ponto de corte ≥ -0,20- apresentou qualidade de ajuste aceitável. No ponto de corte ≥ -0,25-, a rotação promax obteve o melhor ajuste. Os efeitos das rotações nos padrões alimentares diferiram segundo o ponto de corte de carga fatorial utilizado na análise fato-rial exploratória.

El estudio tuvo como objetivo investigar los efectos de los métodos de rotación en la interpretabilidad y validez de un constructo de patrones alimentarios, derivados de una muestra representativa de 1.102 adultos brasileños. Los patrones se derivaron de un análisis factorial exploratorio. Se aplicaron las rotaciones ortogonal (varimax) y oblicua (promax, oblimin directa). La validez de constructo de los patrones fue evaluada por un análisis factorial confirmatorio, según los puntos de corte de cargas factoriales: (≥ -0,20- y ≥ -0.25-). Se analizaron los índices de ajuste del modelo. Se observaron diferencias en la composición e interpretación del primer factor entre varimax y promax/oblimin en el punto de corte ≥ -0,20-. En el punto de corte ≥ -0,25-, ya no se observaron diferencias. Ninguno de los patrones derivados en el punto de corte ≥ -0,20- presentaron un ajuste del modelo aceptable. En el punto de corte ≥ -0,25-, la rotación promax produjo el mejor ajuste. Los efectos de las rotaciones factoriales en los patrones fueron variables, según el punto de corte de carga factorial utilizado en análisis factorial exploratorio.

Betaína e Colina dietéticas relacionadas à homocisteína plasmática: estudo de base populacional, São Paulo, Brasil / Betaine and Choline Intakes are related to total plasma homocysteine: health survey of São Paulo, Brazil

Fundamentos: Elevadas concentrações de homocisteína plasmática (Hcyp) têm sido associadas ao risco aumentado de doenças cardiovasculares. A Hcyp pode ser diminuída por meio da remetilação à metionina, que usa folato ou betaína como doador do grupo metil.Objetivos: Avaliar a ingestão de betaína e colina e sua relação com a homocisteína em residentes do município de São Paulo. Métodos: Obtidos dados de 584 indivíduos, de ambos os sexos, a partir do estudo de base populacional ISA-SP 2008. Médias geométricas de Hcyp foram analisadas de acordo com tercis de ingestão de colina e betaína e foi aplicado teste de tendência.Resultados: Foram analisados 584 indivíduos: 222 (38,0%) homens e 362 (62,0%) mulheres, com média de idade 55,0±19,0 anos. A prevalência de hiper-homocisteinemia foi maior entre os homens (28,0%), idosos (21,0%) e indivíduos com menor renda familiar (21,0%). Cerca de 31,0% dos indivíduos com hiper-homocisteinemia apresentou deficiência de folato (<7,5 nmol/L) e 26,0%, deficiência de vitamina B12 (<200 pmol/L). Observou-se diminuição nas médias geométricas de homocisteína conforme aumento nos tercis de betaína em ambos os sexos,adultos, eutróficos e em todas as categorias de escolaridade. A colina esteve relacionada à Hcyp em ambos os sexos, indivíduos de maior renda familiar, não fumantes e consumidores de bebidas alcoólicas. Conclusões: Este estudo sugere a importância da ingestão de betaína por sua associação inversa com a concentração de Hcyp em adultos e idosos do município de São Paulo. A colina desempenhou papel protetor em subgrupos específicos da população.

Background: High concentrations of plasma homocysteine (Hcyp) have been associated with increased risk of cardiovascular diseases. Hcyp can be decreased by remethylation to methionine, which uses folate or betaine as a donor of the methyl group. Objectives: To evaluate the intake of betaine and choline and its relation to homocysteine in residents of the city of São Paulo. Methods: Data from 584 individual, of both sexes, from the population-based study ISA-SP 2008. Geometric averages of Hcyp were analyzed according to choline and betaine intake tertiles and trend test was applied. Results: The study analyzed 584 individuals: 222 (38.0%) men and 362 (62.0%) women, mean age 55.0 ± 19.0 years. The prevalence of hyperhomocysteinemia was higher among men (28.0%), the elderly (21.0%) and those with lower household income (21.0%). Approximately 31.0% of individual with hyperhomocysteinemia presented folate deficiency (<7.5 nmol/L) and 26.0% presented vitamin B12 deficiency (<200 pmol/L). There was a decrease in the geometric means of homocysteine according to an increase in betaine tertiles in both sexes, adults, normal and in all categories of education. Choline was related to Hcyp in both sexes, higherhousehold income individuals, non-smokers and alcohol consumers. Conclusions: This study suggests the importance of betaine intake due to its inverse relationship with the concentration of Hcyp in adults and elderly in the city of São Paulo. Choline played a protective role in specific subgroups of the population.