ABSTRACT
BACKGROUND AND PURPOSE: The aim was to evaluate the relationship between insomnia and psychiatric disorders in general hospital inpatients. PATIENTS AND METHODS: Information about insomnia was collected using a structured and codified questionnaire adapted from a previously validated one in Brazil. For Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) psychiatric diagnosis, the Portuguese version of the International Neuropsychiatric Interview (MINI) was used. RESULTS: Out of the 200 patients interviewed, 56.5% complained of insomnia, and 50.0% suffered from at least one psychiatric disorder. Major depressive episode (MDE) (P<0.001), generalized anxiety disorder (P=0.025) and suicide risk (P=0.034) were associated with insomnia (univariate analysis). The results of the multivariate analysis showed that only MDE had a statistically significant association with insomnia (OR=3.6; 95% CI=1.9-6.9). CONCLUSIONS: This study found a high prevalence of psychiatric disorders and insomnia in a general hospital population and found that insomnia can be a marker for MDE.
Subject(s)
Hospitalization , Hospitals, General , Mental Disorders/complications , Sleep Initiation and Maintenance Disorders/complications , Adolescent , Adult , Aged , Brazil , Female , Humans , Interview, Psychological , Length of Stay , Male , Mental Disorders/epidemiology , Middle Aged , Prevalence , Sleep Initiation and Maintenance Disorders/epidemiology , Surveys and QuestionnairesABSTRACT
Este trabalho tem o objetivo de analisar a eficácia e segurança do aripiprazol no tratamento de pacientes esquizofrênicos. O aripiprazol é um anti-psicótico atípico diferente dos outros por ser um agonista parcial de receptores dopaminérgicos ou melhor é um estabilizador dopaminérgico. Deste estudo participaram 22 pacientes em ambulatório. A eficácia foi avaliada pela PANSS, e a segurança pela ESRS.
