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1.
Psychiatry Res ; 244: 165-70, 2016 Oct 30.
Article in English | MEDLINE | ID: mdl-27479108

ABSTRACT

Clinical correlates of plasma Brain-Derived Neurotrophic Factor (BDNF) have been investigated in a clinical population with Post Traumatic Stress Disorder (PTSD) symptoms and healthy control subjects who survived to the L'Aquila 2009 earthquake. Twenty-six outpatients and 14 control subjects were recruited. Assessments included: Structured Clinical Interview for DSM-IV Axis-I disorders Patient Version, Trauma and Loss Spectrum-Self Report (TALS-SR) for post-traumatic spectrum symptoms. Thirteen patients were diagnosed as Full PTSD and 13 as Partial PTSD. The subjects with full-blown PTSD showed lower BDNF level than subjects with partial PTSD and controls. Different relationship patterns of BDNF with post-traumatic stress spectrum symptoms have been reported in the three samples. Our findings add more insight on the mechanisms regulating BDNF levels in response to stress and further proofs of the utility of the distinction of PTSD into full and partial categories.


Subject(s)
Brain-Derived Neurotrophic Factor/blood , Disasters , Earthquakes , Stress Disorders, Post-Traumatic/blood , Adult , Case-Control Studies , Diagnostic and Statistical Manual of Mental Disorders , Female , Humans , Italy , Male , Middle Aged , Self Report , Severity of Illness Index , Stress Disorders, Post-Traumatic/psychology
2.
Community Ment Health J ; 51(4): 504-8, 2015 May.
Article in English | MEDLINE | ID: mdl-25540028

ABSTRACT

This study investigated the use of the facilities for the mental health by the population affected by the L'Aquila (Italy) 2009 earthquake. The data about the activities of the Mental Health Centre of L'Aquila during the years from 2008 to 2010 were obtained by the service Information System. In the months following the event the percentage of referrals was reduced. Failure to use specialized facilities after disasters should not be seen as reassuring. It is conceivable that a relevant rate of frank or sub-threshold psychopathology is present that the traditional mental health facilities may not be able to intercept.


Subject(s)
Community Mental Health Services/statistics & numerical data , Disasters , Earthquakes , Community Mental Health Services/trends , Humans , Italy , Needs Assessment
4.
Ann Ist Super Sanita ; 48(2): 132-7, 2012.
Article in English | MEDLINE | ID: mdl-22751555

ABSTRACT

INTRODUCTION: In the present work we describe the mental health condition of L'Aquila population in the aftermath of the earthquake in terms of structural, process and outcome perspectives. METHOD: Literature revision of the published reports on the L'Aquila earthquake has been performed. RESULTS: Although important psychological distress has been reported by the population, capacity of resilience can be observed. However if resilient mechanisms intervened in immediate aftermath of the earthquake, important dangers are conceivable in the current medium-long-term perspective due to the long-lasting alterations of day-to-day life and the disruption of social networks that can be well associated with mental health problems. CONCLUSIONS: In a condition such as an earthquake, the immediate physical, medical, and emergency rescue needs must be addressed initially. However training first responders to identify psychological distress symptoms would be important for mental health triage in the field.


Subject(s)
Earthquakes , Mass Casualty Incidents , Mental Disorders/epidemiology , Mental Health Services/statistics & numerical data , Stress, Psychological/epidemiology , Adaptation, Psychological , Adolescent , Adult , Age Factors , Antidepressive Agents/therapeutic use , Antipsychotic Agents/therapeutic use , Bereavement , Child , Child Development Disorders, Pervasive/epidemiology , Comorbidity , Depression/diagnosis , Depression/drug therapy , Depression/epidemiology , Depression/etiology , Drug Utilization , Female , Humans , Italy , Male , Mental Disorders/drug therapy , Mental Disorders/psychology , Practice Patterns, Physicians'/statistics & numerical data , Psychotic Disorders/drug therapy , Psychotic Disorders/epidemiology , Resilience, Psychological , Sex Factors , Stress Disorders, Post-Traumatic/diagnosis , Stress Disorders, Post-Traumatic/drug therapy , Stress Disorders, Post-Traumatic/epidemiology , Stress Disorders, Post-Traumatic/etiology , Stress, Psychological/etiology , Surveys and Questionnaires , Triage
5.
ACS Nano ; 6(1): 979-85, 2012 Jan 24.
Article in English | MEDLINE | ID: mdl-22176349

ABSTRACT

We use low-cost hole-mask colloidal nanolithography to manufacture large-area resonant split-ring metamaterials and measure their infrared optical properties. This novel substrate is employed for antenna-assisted surface-enhanced infrared absorption measurements using octadecanethiol (ODT) and deuterated ODT, which demonstrates easy adjustability of our material to vibrational modes. Our method has the potential to make resonant plasmon-enhanced infrared spectroscopy a standard lab tool in biology, pharmacology, and medicine.


Subject(s)
Nanostructures/chemistry , Nanostructures/ultrastructure , Photography/methods , Surface Plasmon Resonance/methods , Absorption , Colloids , Infrared Rays , Materials Testing , Particle Size , Porosity , Refractometry
7.
Convuls Ther ; 8(4): 258-261, 1992.
Article in English | MEDLINE | ID: mdl-11941176

ABSTRACT

Electroencephalographic estimates of electroconvulsive therapy (ECT)-induced seizure duration were obtained in 141 patients with major depression (n = 41) or schizophrenia (n = 100). A slight reduction in seizure duration across a course of ECT failed to reach statistical significance and was unrelated to clinical improvement.

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