ABSTRACT
O Ricinus communis L. pertence à família das Euforbiáceas, possui frutos típicos de onde é extraído o óleo de rícino, altamente tóxico. Neste estudo foi analisado o efeito do extrato de Ricinus communis L na marcação de hemácias com Tc-99m através do controle radioquímico. Os resultados mostraram que no controle radioquímico por meio da cromatografia, foi observado que o extrato marcado com Tc-99m mostrou duas frações com 130.007 e 494.592 cpm, e na marcação de hemácias, com por centoATI de 61.88 e 41.32 por cento nas frações 1 e 2. Foi concluído que o extrato de R. communis L. altera a captação do Tc-99m in vitro, competindo com o material radioativo em possíveis sítios de ligação nas células vermelhas do sangue, como a capacidade de oxidação do íon estanoso ou por competição com o íon pertecnetato.
Ricinus communis L. belongs to the Euphorbiaceae family, from whose fruits the ricin oil is extracted, highly toxic. In this study it was analyzed the effect of the extract of Ricinus communis L. in the labeling of red blood cells with Tc-99m through the radiochemical control. The results showed that in the radiochemical control through chromatography, it was observed that the extract labeled with Tc-99m showed two fractions with 130.007 and 494.592 cpm, and in the labeling of red blood cells, with percentATI of 61.88 and 41.32 percent in the fractions 1 and 2. It has been concluded that the extract of Ricinus communis alters the captivating of Tc-99m in vitro, competing with the radioactive material in the possible binding sites of the red blood cells, as well in the capacity of oxidation of the stannous ion or by competition with the pertechnetate ion.
ABSTRACT
The aim of the present study was to observe how the exposition of the pregnant rats to the electromagnetic field (EMF), with frequency of 60 Hz, magnetic field of 3 microT for 2 h per day and/or using the so-called regional basic diet (RBD) influenced the reflex maturation in their offspring. Four groups were formed: Group A (casein), B (casein and EMF), C (RBD) and D (RBD and EMF). The diet manipulation occurred during the pregnancy. The reflexes--assessed daily between 12:00 and 14:00--were: palm grasp (PG), righting reflex (RR), cliff avoidance (CA), vibrissae placing (VP), negative geotaxis (NG), auditory startle (AS) and free-fall righting (FFR). The association between EMF and deficient diet caused a delay in all reflexes when compared with Group A. When the diets were compared with both groups exposed to EMF, the delay occurred in the RR, VP, NG and CA in Group D. In the Groups C and A, the delay was observed in RR, CA, VP, NG, AS and PG. In relation to the EMF, Group B differed from Group A in CA, AS, FFR and PG and Group D differed from C in the PG. In conclusion, all the reflexes studied in this research were delayed by the association of the EMF with undernutrition during pregnancy.
