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1.
J Prosthet Dent ; 81(4): 392-8, 1999 Apr.
Article in English | MEDLINE | ID: mdl-10095207

ABSTRACT

STATEMENT OF PROBLEM: A working cast with dies that accurately record the prepared abutments, surrounding soft tissues, and adjacent and opposing teeth is necessary. PURPOSE: This study compared the accuracy of the direct and transfer coping methods in recording the vertical and horizontal dimensional relationship of a pair of removable dies in a working cast before and after separation from the stone base. Among the procedures used for making impressions of abutments for fixed partial dentures, the transfer coping procedure has specific advantages. In particular, where there are multiple abutments, this procedure, in which individual impressions are made of the abutments, transfer copings are made, and a transfer impression of the copings is used for seating the dies and fabrication of a dental stone base, is useful. METHODS: Two groups of working casts were fabricated from a stone master cast containing 2 ivorine teeth to simulate abutments. The first group of working casts was fabricated directly from the elastomeric impression of the abutments using a 2-pour procedure. The second group of working casts was made using the transfer coping procedure. RESULTS: When the interdie dimensions in each group were compared with that of the master cast, after separation and replacement of the dies in the stone base, the differences were less than 100 microm and similar for both the direct and transfer coping techniques. CONCLUSIONS: These findings show that either procedure is equally effective in positioning the dies in the working casts.


Subject(s)
Dental Casting Technique/standards , Models, Dental/standards , Analysis of Variance , Dental Abutments , Dental Casting Technique/statistics & numerical data , Dental Impression Materials , Dental Impression Technique/statistics & numerical data , Denture, Partial, Fixed , Humans , Models, Dental/statistics & numerical data , Molar , Polyvinyls , Reproducibility of Results , Siloxanes
2.
Recenti Prog Med ; 87(1): 23-6, 1996 Jan.
Article in Italian | MEDLINE | ID: mdl-8711251

ABSTRACT

Bleeding from small bowel is a quite rare event and often is a diagnostic challenge to physician and surgeon. We present a case of a patient with an acute massive haemorrhage due to jejunal diverticulosis and with an unusual clinical setting. The site of bleeding was localized by scan with radiotagged erythrocytes, but the diagnosis of jejunal diverticule was evident only at laparotomy. The patient underwent to surgical resection of the affected bowel (40 cm). Although jejunal diverticula are considered a rare source of gastrointestinal haemorrhage, we suggest that this disorder must be considered in all patients with occult gastrointestinal bleeding especially in the elderly.


Subject(s)
Diverticulum/complications , Diverticulum/diagnosis , Gastrointestinal Hemorrhage/etiology , Jejunal Diseases/complications , Jejunal Diseases/diagnosis , Aged , Diagnosis, Differential , Diverticulum/surgery , Humans , Jejunal Diseases/surgery , Male
3.
Clin Exp Rheumatol ; 13 Suppl 13: S201-3, 1995.
Article in English | MEDLINE | ID: mdl-8730507

ABSTRACT

OBJECTIVE: To evaluate the effect of cyclosporine in the treatment of type II mixed cryoglobulinemia, after the failure of more conventional therapies. METHODS: Two patients with type II mixed cryoglobulinemia associated with chronic HCV infection, purpura, liver disease, and sensitive/motor neuropathy were treated with cyclosporine (2.5 mg/Kg/b.w.), after their failure to respond to treatment with corticosteroid, immunosuppressive drugs, interferon, and plasmapheresis. RESULTS: In both patients an improvement in the clinical manifestations (purpura and peripheral neuropathy), laboratory results (serum transaminases and cryocrit), and liver histology was seen, as well as the disappearance of bone marrow B-cell lymphoproliferation. CONCLUSION: Cyclosporine may be useful in the treatment of type II mixed cryoglobulinemia with prominent autoimmune clinical manifestations, although further studies are needed to better define the selection of patients.


Subject(s)
Antirheumatic Agents/therapeutic use , Cryoglobulinemia/drug therapy , Cyclosporine/therapeutic use , Cryoglobulinemia/complications , Cryoglobulinemia/virology , Female , Hepacivirus/genetics , Humans , Italy , Middle Aged , Pilot Projects , Purpura/complications , Purpura/drug therapy , RNA, Viral/analysis
4.
Ann Ital Med Int ; 10(2): 98-101, 1995.
Article in Italian | MEDLINE | ID: mdl-7619658

ABSTRACT

The frequent association of chronic hepatitic C virus (HCV) infection and type II mixed cryoglobulinemia is considered to be one of the possible signs of interaction between the virus and the immune system. This could also be the case for the appearance of anti-GOR antibodies in serum, as they react with both viral and host antigens. We studied a group of patients with chronic hepatitis C infection and a group with type II mixed cryoglobulinemia associated with HCV infection to ascertain if anti-GOR or other non-organ specific autoantibodies were present in the serum. We found no significant difference between the two groups in presence, prevalence or titer of anti-GOR or other autoantibodies. Moreover, the expression of anti-GOR does not seem to influence the severity of liver damage. Our data support the hypothesis that anti-GOR antibodies are a simple expression of molecular mimicry between viral and human epitopes.


Subject(s)
Autoantibodies/analysis , Cryoglobulinemia/immunology , Hepatitis C/immunology , Adult , Aged , Cryoglobulinemia/complications , Enzyme-Linked Immunosorbent Assay , Female , Fluorescent Antibody Technique , Hepacivirus/genetics , Hepatitis Antibodies/analysis , Hepatitis C/complications , Humans , Kidney/immunology , Male , Microsomes/immunology , Microsomes, Liver/immunology , Middle Aged , RNA, Viral/analysis
5.
Haematologica ; 78(1): 58-60, 1993.
Article in English | MEDLINE | ID: mdl-8491422

ABSTRACT

Parenchymal neoplastic invasion of the kidneys is a common postmortem finding in patients who have died from advanced non Hodgkin's lymphomas (NHL). However, it rarely causes major clinical consequences, such as impairment of glomerular and tubular function, acute or rapidly progressive renal failure. Renal involvement is even less frequent as a first manifestation of NHL, the so-called "primary" renal lymphoma. A review of the main clinical, diagnostic and pathological aspects of three cases observed in our division is presented here.


Subject(s)
Kidney Neoplasms/pathology , Lymphoma, Follicular/pathology , Lymphoma, Large-Cell, Immunoblastic/pathology , Lymphoma, Non-Hodgkin/pathology , Acute Kidney Injury/etiology , Adult , Female , Humans , Kidney Neoplasms/complications , Lymphoma, Follicular/complications , Male , Middle Aged , Nephrotic Syndrome/etiology , Skin Neoplasms/complications , Skin Neoplasms/pathology
6.
Recenti Prog Med ; 82(4): 233-5, 1991 Apr.
Article in English | MEDLINE | ID: mdl-1857844

ABSTRACT

Simvastatin, recently introduced in clinical practice for pharmacological treatment of hypercholesterolemia, has been found to cause minor and reversible elevations of serum transaminases. We report a case of acute cholestatic hepatitis during simvastatin therapy. Clinical, biochemical, immunological, and histological findings were consistent with a simvastatin-induced liver damage through an immunological-mediated mechanism. This case suggests a careful monitoring of liver function tests during simvastatin therapy, and caution in continuing simvastatin administration when elevations of serum transaminases take place.


Subject(s)
Anticholesteremic Agents/adverse effects , Chemical and Drug Induced Liver Injury/etiology , Hydroxymethylglutaryl-CoA Reductase Inhibitors , Lovastatin/analogs & derivatives , Acute Disease , Chemical and Drug Induced Liver Injury/pathology , Cholestasis/chemically induced , Cholestasis/pathology , Female , Humans , Liver/pathology , Lovastatin/adverse effects , Middle Aged , Simvastatin
7.
Minerva Med ; 75(38): 2179-92, 1984 Oct 06.
Article in Italian | MEDLINE | ID: mdl-6542181

ABSTRACT

Behçet disease is characterised by a triple symptom picture (genital and oral aphthae, ocular lesions) named after the Turkish dermatologist, Hulusi Behçet. It is found all over the world, but is particularly frequent in Japan and the Mediterranean basin. Adult males are primarily affected. The classic symptomatological triad may be accompanied by other manifestations involving the skin (hypersensitivity to microtrauma is a peculiar feature), joints, nervous system, gastroenteric system, cardiovascular system (phlebitis, phlebothrombosis), lungs and kidneys. There is a chronic course marked by periods of exacerbation and remission, which may last for years. Diagnosis is clinical only, since neither the laboratory data nor the histopathological signs of vasculitis are truly pathognomonic. The prognosis quoad valetudinem is uncertain with regard to the eye lesions, which may result in blindness. The prognosis quoad vitam is usually good, though it is poor if the nervous system is involved, or in the event of lung and large vessel lesions, since death may occur from haemoptysis or the rupture of aneurysms.


Subject(s)
Behcet Syndrome/pathology , Uveitis, Anterior/complications , Behcet Syndrome/diagnosis , Brain Stem/pathology , Dermatitis/complications , Diagnosis, Differential , Encephalitis/complications , Humans , Intestinal Mucosa/pathology , Joint Diseases/complications , Lung Diseases/complications , Male , Meningitis/complications , Paralysis/complications , Pericarditis/complications , Prognosis , Stomatitis, Aphthous/complications
8.
Minerva Med ; 75(39): 2263-82, 1984 Oct 13.
Article in Italian | MEDLINE | ID: mdl-6334250

ABSTRACT

The aetiopathogenesis of Behcet's disease is still not known. In the light of current knowledge, the most likely hypothesis seems to be that of an autoimmune reaction set off by viral, bacterial or other antigens. The reaction may manifest itself in the vascular system, and cause vasculitic conditions in genetically susceptible subjects. The existence of a constitutional susceptibility factor would seem to be confirmed by the high and significant incidence of determinant histocompatibility antigens: HLA-B5 in Japan and in Mediterranean countries, HLA-A2 and HLA-A28 in Great Britain and the United States. Corticosteroids are most commonly used to treat the disease; immunosuppressants are also recommended--possibly in association with corticosteroids. Three personally observed cases of Behcet's disease are reported. The first was an example of the disease in its complete form (oral and genital aphthae, ocular lesions); the second case incomplete (no genital aphthae); and the third characterised by severe neurological involvement (neuro-Behcet).


Subject(s)
Behcet Syndrome/etiology , HLA-B Antigens , Adult , Antifungal Agents/therapeutic use , Autoimmune Diseases/immunology , Behcet Syndrome/drug therapy , Behcet Syndrome/immunology , Brain Diseases/etiology , Cortisone/therapeutic use , Cyclophosphamide/therapeutic use , Dermatitis/etiology , Disease Susceptibility , Female , HLA Antigens/immunology , HLA-B27 Antigen , Humans , Joint Diseases/etiology , Male , Stomatitis, Aphthous/etiology , Thymopoietins/therapeutic use , Vision Disorders/etiology
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