[Experimental value of the biliary excretion of the conjugated form of SBP by the in vivo liver and by the isolated and perfused liver]. / Intérêt expérimental de l'élimination biliaire de la forme conjuguée de la BSP par le foie, in vivo et par le foie isolé et perfusé

We first studied the uptake and excretion of the dye BSP by the isolated and perfused rat liver and by the rat liver in vivo. We then studied BSP-glutathion conjugation with these same methods. We found that benziodarone which induces a marked decrease of conjugation is able to inhibit in vitro the combination BSP-glutathion.