ABSTRACT
Transrectal ultrasound (TRUS) was used to predict tumor stage in 43 patients prior to radical prostatectomy. For assessing extracapsular extension, the sensitivity was 54 percent, specificity 58 percent, and accuracy 56 percent. For detecting seminal vesicle involvement, the sensitivity was 60 percent, specificity 89 percent, and accuracy 82 percent. The predominant tumor echo pattern was isoechoic in 37 percent of cases, mixed (hyper-, iso-, and hypoechoic) in 47 percent, and hypoechoic in 16 percent. An anterior-posterior to transverse dimension ratio of greater than 0.8 suggested diffuse involvement of the prostate with an increased chance of extracapsular spread.
Subject(s)
Adenocarcinoma/pathology , Prostatic Neoplasms/pathology , Ultrasonography , Adenocarcinoma/surgery , Humans , Lymphatic Metastasis , Male , Neoplasm Staging , Prospective Studies , Prostatectomy , Prostatic Neoplasms/surgery , Seminal Vesicles/pathologySubject(s)
Hepatitis/etiology , Syphilis/complications , Acute Disease , Adult , Hepatitis/diagnosis , Humans , Male , Syphilis/diagnosisABSTRACT
There are many complications of a jejunoileal bypass for obesity. I report what is, to my knowledge, a previously unrecognized complication--granulomatous colitis and ileitis. Caution is urged in recommending this procedure for the treatment of obesity.
Subject(s)
Crohn Disease/etiology , Ileitis/etiology , Ileum/surgery , Jejunum/surgery , Postoperative Complications , Adult , Female , Humans , Obesity/therapyABSTRACT
The spontaneous development of a cytomegalovirus infection in a healthy adult is described. This illness manifested with fever, headache, malaise, an absolute lymphocytosis with atypical lymphocytes, and liver function abnormalities, but without tonsillitis, pharyngitis, lymphadenopathy, or splenomegaly. Aseptic meningitis also was present. The pathogenesis of cytomegalovirus mononucelosis and its relationship to other related syndromes are discussed.
Subject(s)
Cytomegalovirus Infections/microbiology , Infectious Mononucleosis/microbiology , Meningitis, Aseptic/microbiology , Meningitis/microbiology , Antibodies, Viral/analysis , Cytomegalovirus/pathogenicity , Cytomegalovirus Infections/immunology , Cytomegalovirus Infections/pathology , Female , Humans , Infectious Mononucleosis/immunology , Lymphocytosis/pathology , Meningitis, Aseptic/immunology , Middle AgedABSTRACT
A patient with clindamycin-associated pseudomembranous colitis is presented. His dramatic response to prednisone suggested an immunologic basis of the disease process. This aspect of etiology and therapy has not been emphasized previously. Similar patients with clindamycin-associated pseudomembranous colitis should be sought out and consideration should be given to this type of treatment.
Subject(s)
Clindamycin/adverse effects , Prednisone/therapeutic use , Aged , Humans , MaleABSTRACT
The patient presented had well-documented benign lymphoepithelial lesion, many years before the appearance of neoplastic disease. The relationship between this type of lesion and the later development of neoplasia is unclear, but evidence points to its existence, and further study is needed to clarify its frequency and significance. It appears that in some patients the benign lymphoepithelial lesion is a forerunner of the neoplastic process, and thus may serve as another clinical clue to the early diagnosis of neoplasia, especially that on the lymphoreticuloendothelial cell type.
