ABSTRACT
The authors report the case of a 77-year-old woman suffering from ischemic cardiopathy, arterial hypertension and NID diabetes mellitus who was hospitalised for diabetic retinopathy. Following the topical administration of a drop of phenylephrine in the right eye, in preparation for fluoroangiography, she suffered an attack of angina pectoris. This event was clearly identified by a ECG carried out at the time which highlighted the sublevelling of the ST tract in the precordial derivations V2-V5, and by ecocardiographic imaging that showed septo-apical, anterior-apical and anterior-median transient segmentary hypokinesia. This case underlines the need for prudence and emphasises the need to regard patients suffering from ischemic cardiopathy as high-risk when undergoing diagnostic tests, in particular if these involve the use of vasoactive drugs.
Subject(s)
Angina Pectoris/chemically induced , Diabetic Retinopathy/complications , Myocardial Ischemia/complications , Phenylephrine/administration & dosage , Vasoconstrictor Agents/administration & dosage , Aged , Angina Pectoris/diagnosis , Diabetes Mellitus, Type 2 , Diabetic Retinopathy/diagnosis , Electrocardiography , Female , Humans , Ophthalmic Solutions/adverse effects , Phenylephrine/adverse effects , Pregnancy , Risk Factors , Vasoconstrictor Agents/adverse effectsABSTRACT
Physiopathological basis and methodological implications of the radioimmunological estimation of plasma C-peptide, as a test of beta cell secretory activity, are reviewed. Personal results are reported concerning C-peptide assay, both in basal and stimulative conditions, in insulindependent long-and short-term diabetes. In 1 case of organic, and 2 cases of functional hyperinsulinism, the test gave useful clinical information. The method of L. Heding-Novo Research Institute, Bagsvaerd, Denmark-, with previous elimination of proinsulin and insulinantibody in patients with high values of IgG insulin binding, proved to be suitable to endocrinological routine.
