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1.
Arq Neuropsiquiatr ; 64(2B): 441-5, 2006 Jun.
Article in Portuguese | MEDLINE | ID: mdl-16917616

ABSTRACT

UNLABELLED: Glioblastoma multiforme (GBM) is the glial tumor with the highest grade of malignity. It mainly affects the cerebral hemispheres, presenting general or focal signs and symptoms, which depend on the size, the location of the lesion and rate of growth of the tumor. OBJECTIVE: To analyze the relationship between motor impairment and GBM topography. METHOD: We studied 43 cases of GBM, related to the age, gender, localization and motor impairment. RESULTS: The occurrence of the tumor was preponderant in adults (mean age 55 years old), men (55.82%), and frontal lobe (approximately 40%). The principal motor impairment was hemiparesis, with the exception of 2 cases in the frontal lobe, 2 temporal, 1 parietal, 1 occipital and 1 frontotemporal. CONCLUSION: The clinical-topographic findings lead to consider the infiltrative effects (broad lesions) are responsible for the motor impairment rather than compressive effects (located lesions).


Subject(s)
Brain Neoplasms/complications , Glioblastoma/complications , Movement Disorders/etiology , Adult , Aged , Aged, 80 and over , Brain Neoplasms/pathology , Female , Glioblastoma/pathology , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Retrospective Studies , Tomography, Emission-Computed
2.
Arq. neuropsiquiatr ; 64(2b): 441-445, jun. 2006. tab, graf
Article in Portuguese | LILACS | ID: lil-433286

ABSTRACT

O glioblastoma multiforme (GBM) é o tumor glial com maior grau de malignidade. Acomete principalmente os hemisférios cerebrais apresentando sintomas e sinais focais ou gerais, relacionados ao tamanho, localização e taxa de crescimento tumoral. OBJETIVO: Analisar a relação do déficit motor com a topografia do GBM. MÉTODO: Foram estudados 43 casos de GBM, referidos quanto à idade, sexo, localização e a síndrome motora. RESULTADOS: O tumor predominou em adultos (média de 55 anos), sexo masculino (55,82 por cento), localização frontal (aproximadamente 40 por cento). A hemiparesia prevaleceu como distúrbio motor, somente não ocorrendo em 2 casos de lesão frontal, 2 temporais, 1 parietal, 1 occipital e 1 fronto-temporal. CONCLUSÃO: Os achados clínico-topográficos favorecem os efeitos infiltrativos (lesões extensas) como responsáveis pela síndrome motora em detrimento aos efeitos compressivos (lesões localizadas).


Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Brain Neoplasms/complications , Glioblastoma/complications , Movement Disorders/etiology , Brain Neoplasms/pathology , Glioblastoma/pathology , Magnetic Resonance Imaging , Retrospective Studies , Tomography, Emission-Computed
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