Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 22
Filter
1.
J Vasc Bras ; 22: e20220098, 2023.
Article in English | MEDLINE | ID: mdl-37790890

ABSTRACT

Background: Infection is the most frequent complication of central venous catheters used for hemodialysis. Objectives: The purpose of this study was to the determine the central venous catheter-related infection rate at a dialysis center in the Brazilian state of Amazonas and to identify risk factors and the microbiological profile of the infections. Methods: This was an observational study with prospective data collection over a 12-month period by chart analysis and face-to-face interviews with patients undergoing hemodialysis using central venous catheters at a dialysis center. Results: 96 central venous catheters were analyzed in 48 patients. 78 of these were non-tunneled central venous catheters (81.3%) and 18 were tunneled central venous catheters (18.7%), 53.1% of the catheters were exchanged because of infection and blood cultures were obtained from 35.2% of the patients who had catheter-related infections. Gram-negative bacteria were isolated from five of the nine blood cultures in which there was bacterial growth and Gram-positive bacteria were isolated from the other four. The most commonly isolated bacteria was Staphylococcus hominis, found in 22.2% of positive blood cultures. Conclusion: The overall hemodialysis venous catheter infection rate was 10.1 episodes/1000 catheter days, 15.1 episodes/1000 catheters days in non-tunneled catheters and 3.3 episodes/1000 catheters days in tunneled catheters. The infection predisposing factors identified were use of non-tunneled catheters and having 2 hemodialysis sessions per week. Regarding the microbiological profile, over half of the bacteria isolated were Gram-negative.

2.
J. vasc. bras ; 22: e20220098, 2023. tab, graf
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1448592

ABSTRACT

Resumo Contexto Infecção é a complicação mais frequente do uso de cateter venoso central em hemodiálise. Objetivo O propósito do trabalho foi determinar a taxa de incidência de infecções de cateteres venosos centrais para hemodiálise em um centro de diálise no estado do Amazonas, bem como seus fatores preditivos, além de traçar o perfil microbiológico dessas infecções. Métodos Trata-se de um estudo observacional, com dados coletados mensalmente e de forma prospectiva, por meio de entrevista e análise de prontuários de pacientes submetidos a hemodiálise por meio de cateteres venosos centrais em um centro de diálise durante um período de 12 meses. Resultados Foram analisados 96 cateteres venosos centrais, de 48 pacientes. Do total, foram 78 cateteres venosos não tunelizados (81,3%) e 18 cateteres venosos tunelizados (18,7%). Dos cateteres acompanhados, 53,1% foram trocados por motivo de infecção, sendo realizada hemocultura de 35,2% dos pacientes que apresentaram infecção de cateter. Quanto ao perfil microbiológico, das nove hemoculturas positivas, em cinco foram isoladas bactérias gram-negativas, e em quatro foram isoladas bactérias gram-positivas. A bactéria mais frequentemente isolada foi a Staphylococcus hominis, presente em 22,2% das hemoculturas positivas. Conclusão A taxa de incidência global de infecção de cateteres venosos centrais foi de 10,1 episódios por 1.000 dias de cateter, sendo de 15,1 nos cateteres não tunelizados e de 3,3 nos cateteres tunelizados. Os fatores preditivos identificados foram o uso de cateter venoso central não tunelizado e a realização de duas sessões de diálise semanais. Quanto ao perfil microbiológico, pouco mais da metade das bactérias isoladas foram gram-negativas.


Abstract Background Infection is the most frequent complication of central venous catheters used for hemodialysis. Objectives The purpose of this study was to the determine the central venous catheter-related infection rate at a dialysis center in the Brazilian state of Amazonas and to identify risk factors and the microbiological profile of the infections. Methods This was an observational study with prospective data collection over a 12-month period by chart analysis and face-to-face interviews with patients undergoing hemodialysis using central venous catheters at a dialysis center. Results 96 central venous catheters were analyzed in 48 patients. 78 of these were non-tunneled central venous catheters (81.3%) and 18 were tunneled central venous catheters (18.7%), 53.1% of the catheters were exchanged because of infection and blood cultures were obtained from 35.2% of the patients who had catheter-related infections. Gram-negative bacteria were isolated from five of the nine blood cultures in which there was bacterial growth and Gram-positive bacteria were isolated from the other four. The most commonly isolated bacteria was Staphylococcus hominis, found in 22.2% of positive blood cultures. Conclusion The overall hemodialysis venous catheter infection rate was 10.1 episodes/1000 catheter days, 15.1 episodes/1000 catheters days in non-tunneled catheters and 3.3 episodes/1000 catheters days in tunneled catheters. The infection predisposing factors identified were use of non-tunneled catheters and having 2 hemodialysis sessions per week. Regarding the microbiological profile, over half of the bacteria isolated were Gram-negative.

3.
J Vasc Bras ; 21: e20220032, 2022.
Article in English | MEDLINE | ID: mdl-36505346

ABSTRACT

Clinical Practice Guidelines (CPG) are structured recommendations based on systematic reviews of the available evidence and are useful tools to support clinical decision-making. However, studies have raised concerns about the methodological and scientific quality of several CPG, which can affect their application in clinical practice. The objective of this study was to perform a systematic appraisal of the methodological quality of carotid atherosclerotic disease clinical guidelines, published from 2000 to 2019, using the AGREE II instrument (Appraisal of Guidelines for Research and Evaluation Instrument II). The appraisers independently assessed the quality of the CPG included in the study for each of the 6 domains of the AGREE II tool. The CPG were rated as high, moderate, or low quality using a points scale. A total of 9 CPGs were selected for appraisal. Except for domain 2 (kappa=0.715), excellent agreement was observed between the appraisers (kappa>0.75). Five of the CPGs were rated as high overall methodological quality rating, 5 were rated as moderate overall methodological quality, and 2 were rated low overall methodological quality. The authors conclude that: (1) appraisal of carotid atherosclerotic disease clinical guidelines using the AGREE II instrument is feasible, with a high degree of agreement among appraisers; and (2) that most CPGs on the management of atherosclerotic carotid disease have high methodological quality.

4.
Ann Med Surg (Lond) ; 81: 104527, 2022 Sep.
Article in English | MEDLINE | ID: mdl-36147127

ABSTRACT

Introduction: Chronic extrahepatic non-tumoral thrombotic portal vein occlusion in non-cirrhotic patients is a rare condition, affecting 5-10% of patients with portal hypertension. Presentation of case: The present study reports the case of a young patient without previous comorbidities who presented with portal hypertension secondary to chronic extrahepatic non-tumoral thrombotic occlusion of the portal vein. He underwent portal recanalization with a 12 × 80 mm nitinol self-expandable stent and embolization of esophagogastric varices with fibrous springs and cyanoacrylate via transparieto-hepatic access. Immediate resolution of the trans-lesion pressure gradient was obtained transoperatively, while complete remission of esophagogastric varices was verified by endoscopic control during outpatient follow-up. Discussion: Chronic portal vein occlusion is associated or not with liver cirrhosis. The chronic phase is characterized by cavernomatous transformation of the portal vein, which consists of the formation of multiple collaterals that bypass the lesion. This phase usually courses with portal hypertension and consequent variceal gastrointestinal bleeding. Decompression of the portal system through direct recanalization (angioplasty with stenting) is one therapeutic options. Conclusion: We conclude that, in the present case, resolving portal hypertension by direct portal recanalization was a good therapeutic option, as it decompressed the portal system while maintaining the hepatopetal flow.

5.
J. vasc. bras ; 21: e20220032, 2022. tab, graf
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1405501

ABSTRACT

Resumo Diretrizes clínicas (DCs) são recomendações estruturadas baseadas na revisão sistemática da evidência disponível, sendo ferramentas úteis na tomada de decisões clínicas. Entretanto, estudos têm levantado preocupação quanto à qualidade metodológica e científica de várias DCs, que podem afetar sua aplicação na prática clínica. O objetivo do presente estudo foi fazer uma avaliação sistemática da qualidade metodológica das DCs que abordam o tratamento da doença arterial obstrutiva carotídea, publicadas entre 2000 e 2019, utilizando a ferramenta AGREE II (Appraisal of Guidelines Research and Evaluation Instrument II). Os pesquisadores avaliaram independentemente a qualidade das DCs incluídas no estudo em cada um dos seis domínios da ferramenta AGREE II. Por meio de um sistema de pontuação, as DCs foram classificadas em alta, moderada e baixa qualidade. Um total de nove DCs foram selecionadas. Exceto pelo domínio dois (Kappa = 0,715), houve concordância excelente entre os três avaliadores (Kappa > 0,75). Considerando-se a avaliação global da qualidade metodológica das DCs, cinco foram consideradas de alta qualidade (55%), duas foram consideradas de qualidade moderada e duas foram consideradas de baixa qualidade. Concluímos que (1) foi factível a utilização da AGREE II para a avaliação de DCs sobre o tratamento da doença arterial obstrutiva carotídea com alto grau de concordância inter-avaliadores; e que (2) a maioria das DCs disponíveis sobre o tratamento da doença arterial obstrutiva carotídea tem alta qualidade metodológica.


Abstract Clinical Practice Guidelines (CPG) are structured recommendations based on systematic reviews of the available evidence and are useful tools to support clinical decision-making. However, studies have raised concerns about the methodological and scientific quality of several CPG, which can affect their application in clinical practice. The objective of this study was to perform a systematic appraisal of the methodological quality of carotid atherosclerotic disease clinical guidelines, published from 2000 to 2019, using the AGREE II instrument (Appraisal of Guidelines for Research and Evaluation Instrument II). The appraisers independently assessed the quality of the CPG included in the study for each of the 6 domains of the AGREE II tool. The CPG were rated as high, moderate, or low quality using a points scale. A total of 9 CPGs were selected for appraisal. Except for domain 2 (kappa=0.715), excellent agreement was observed between the appraisers (kappa>0.75). Five of the CPGs were rated as high overall methodological quality rating, 5 were rated as moderate overall methodological quality, and 2 were rated low overall methodological quality. The authors conclude that: (1) appraisal of carotid atherosclerotic disease clinical guidelines using the AGREE II instrument is feasible, with a high degree of agreement among appraisers; and (2) that most CPGs on the management of atherosclerotic carotid disease have high methodological quality.

6.
Rev Col Bras Cir ; 47: e20202471, 2020.
Article in Portuguese, English | MEDLINE | ID: mdl-32667581

ABSTRACT

PURPOSE: the purpose of this research was to identify the sociodemographic and microbiological characteristics and antibiotic resistance rates of patients with diabetic foot infections, hospitalized in an emergency reference center. METHODS: it was an observational and transversal study. The sociodemographic data were collected by direct interview with the patients. During the surgical procedures, specimens of tissue of the infected foot lesions were biopsied to be cultured, and for bacterial resistance analysis. RESULTS: the sample consisted of 105 patients. The majority of patierns were men, over 50 years of age, married and with low educational level. There was bacterial growth in 95 of the 105 tissue cultures. In each positive culture only one germ was isolated. There was a high prevalence of germs of the Enterobacteriaceae family (51,5%). Gram-negative germs were isolated in 60% of cultures and the most individually isolated germs were the Gram-positive cocci, Staphylococcus aureus (20%) and Enterococcus faecalis (17,9%). Regarding antibiotic resistance rates, a high frequency of Staphylococcus aureus resistant to methicillin (63,0%) and to ciprofloxacin (55,5%) was found; additionally, 43,5% of the Gram-negative isolated germs were resistant to ciprofloxacin. CONCLUSIONS: the majority of patients were men, over 50 years of age, married and with low educational level. The most prevalent isolated germs from the infected foot lesions were Gram-negative bacteria, resistant to ciprofloxacin, and the individually most isolated germ was the methicillin resistant Staphylococcus aureus.


Subject(s)
Anti-Bacterial Agents/therapeutic use , Diabetic Foot/microbiology , Gram-Negative Bacteria/drug effects , Gram-Negative Bacterial Infections/drug therapy , Gram-Negative Bacterial Infections/microbiology , Gram-Positive Bacteria/drug effects , Gram-Positive Bacterial Infections/drug therapy , Gram-Positive Bacterial Infections/microbiology , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Skin Diseases, Bacterial/microbiology , Aged , Anti-Bacterial Agents/pharmacology , Diabetes Complications , Diabetes Mellitus , Diabetic Foot/drug therapy , Drug Resistance, Microbial , Female , Gram-Negative Bacteria/isolation & purification , Gram-Positive Bacteria/isolation & purification , Humans , Infections , Male , Methicillin-Resistant Staphylococcus aureus/drug effects , Microbial Sensitivity Tests , Middle Aged , Skin Diseases, Bacterial/drug therapy , Staphylococcal Skin Infections/drug therapy , Staphylococcal Skin Infections/epidemiology , Staphylococcal Skin Infections/microbiology
7.
J Vasc Bras ; 19: e20200088, 2020 Dec 11.
Article in English | MEDLINE | ID: mdl-34211526

ABSTRACT

Horseshoe kidney is the most common congenital renal anomaly, occurring in 0.15-0.25% of newborns. The association of a horseshoe kidney with an abdominal aortic aneurysm is rare. Only 0.12% of patients requiring abdominal aortic repair have a horseshoe kidney. This therapeutic challenge constitutes a patient presenting with a symptomatic abdominal aortic aneurysm and a horseshoe kidney. The horseshoe kidney was supplied by 4 renal arteries, 2 of which emerged from the aneurysmal sac. The patient underwent urgent open repair, with transperitoneal exposure, interposition of a bifurcated aorto-bi-iliac Dacron graft and re-implantation of the 2 anomalous renal arteries on the Dacron main body. Postoperatively, the patient was discharged from the intensive care unit on day 3, and discharged home on day 8, maintaining normal serum creatinine.

8.
Rev. Col. Bras. Cir ; 47: e20202471, 2020. tab, graf
Article in English | LILACS | ID: biblio-1136576

ABSTRACT

ABSTRACT Purpose: the purpose of this research was to identify the sociodemographic and microbiological characteristics and antibiotic resistance rates of patients with diabetic foot infections, hospitalized in an emergency reference center. Methods: it was an observational and transversal study. The sociodemographic data were collected by direct interview with the patients. During the surgical procedures, specimens of tissue of the infected foot lesions were biopsied to be cultured, and for bacterial resistance analysis. Results: the sample consisted of 105 patients. The majority of patierns were men, over 50 years of age, married and with low educational level. There was bacterial growth in 95 of the 105 tissue cultures. In each positive culture only one germ was isolated. There was a high prevalence of germs of the Enterobacteriaceae family (51,5%). Gram-negative germs were isolated in 60% of cultures and the most individually isolated germs were the Gram-positive cocci, Staphylococcus aureus (20%) and Enterococcus faecalis (17,9%). Regarding antibiotic resistance rates, a high frequency of Staphylococcus aureus resistant to methicillin (63,0%) and to ciprofloxacin (55,5%) was found; additionally, 43,5% of the Gram-negative isolated germs were resistant to ciprofloxacin. Conclusions: the majority of patients were men, over 50 years of age, married and with low educational level. The most prevalent isolated germs from the infected foot lesions were Gram-negative bacteria, resistant to ciprofloxacin, and the individually most isolated germ was the methicillin resistant Staphylococcus aureus.


RESUMO Objetivo: identificar o perfil sociodemográfico, microbiológico e de resistência bacteriana em pacientes com pé diabético infectado. Métodos: tratou-se de estudo observacional, transversal que avaliou os perfis sóciodemográfico e microbiológico de pacientes portadores de pé diabético infectado internados em Pronto Socorro de referência. Os dados sociodemográficos foram coletados por meio de entrevista. Foram colhidos, durante os procedimentos cirúrgicos, fragmentos de tecidos das lesões podais infectadas para realização de cultura/antibiograma. Resultados: a amostra foi composta por 105 pacientes. O perfil sociodemográfico mais prevalente foi o de pacientes do sexo masculino, acima dos 50 anos, casados e com baixa escolaridade. Das 105 amostras de fragmentos de tecidos colhidos para realização de cultura e antibiograma, 95 foram positivas, com crescimento de um único germe em cada um dos exames. Houve predomínio de germes da família Enterobacteriaceae (51,5%). Germes Gram-negativos foram isolados em 60,0% das culturas e os espécimes mais isolados individualmente foram os cocos Gram-positivos, Staphylococcus aureus (20,0%) e Enterococcus faecalis (17,9%). Considerando-se os perfis de resistência bacteriana, verificou-se alta taxa de Staphylococcus aureus resistente à meticilina (63,0%) e à ciprofloxacino (55,5%); verificou-se, também, que 43,5% dos germes Gram-negativos eram resistentes à ciprofloxacino. Conclusões: o perfil sociodemográfico majoritário, foi o de homens, com mais de 50 anos e com baixa escolaridade. Concluímos que os germes mais prevalentes nas lesões podais dos pacientes diabéticos foram os Gram-negativos, resistentes ao ciprofloxacino e que o germe mais isolado individualmente foi o Staphylococcus aureus resistente à meticilina.


Subject(s)
Humans , Male , Female , Aged , Gram-Positive Bacterial Infections/microbiology , Gram-Positive Bacterial Infections/drug therapy , Gram-Negative Bacterial Infections/microbiology , Gram-Negative Bacterial Infections/drug therapy , Skin Diseases, Bacterial/microbiology , Diabetic Foot/microbiology , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Gram-Negative Bacteria/drug effects , Gram-Positive Bacteria/drug effects , Anti-Bacterial Agents/therapeutic use , Staphylococcal Skin Infections/microbiology , Staphylococcal Skin Infections/drug therapy , Staphylococcal Skin Infections/epidemiology , Drug Resistance, Microbial , Microbial Sensitivity Tests , Skin Diseases, Bacterial/drug therapy , Diabetic Foot/drug therapy , Diabetes Complications , Diabetes Mellitus , Methicillin-Resistant Staphylococcus aureus/drug effects , Gram-Negative Bacteria/isolation & purification , Gram-Positive Bacteria/isolation & purification , Infections , Middle Aged , Anti-Bacterial Agents/pharmacology
9.
Acta Cir Bras ; 34(4): e201900410, 2019 Apr 29.
Article in English | MEDLINE | ID: mdl-31038587

ABSTRACT

PURPOSE: To develop a silicone alternative model of tissue suture simulation to be used in the teaching of surgical technique. METHODS: Twelve alternative models of silicone for tissue suture simulation were manufactured and implemented as a tool for suture pattern training of undergraduate medical students of Universidade Federal do Amazonas. Forty-eight students participated in the research. The evaluation of the proposed model was done through a questionnaire using the Likert scale, in order to verify the student satisfaction index of the alternative resource and its performance as opposed to the model historically used in the discipline, which is to suture in cloths. RESULTS: The alternative model showed satisfactory results, especially with respect to the structural aspect, such as, better perception of anatomical planes, handling and transport. About 89.58% of positive concordant responses demonstrating expressive approval for incorporation of a complementary form of the alternative methodological proposal of the discipline of surgical technique. CONCLUSIONS: The model developed for experimental simulation of tissue sutures has proved to be a fully feasible alternative method for the training of this surgical skill. It is a simple, reproducible and low-cost model.


Subject(s)
Models, Anatomic , Silicones , Simulation Training/methods , Suture Techniques/education , Academic Performance , Clinical Competence , Education, Medical, Undergraduate/methods , Education, Medical, Undergraduate/standards , Humans , Reproducibility of Results , Simulation Training/standards , Students, Medical , Surveys and Questionnaires
10.
Acta cir. bras ; 34(4): e201900410, 2019. tab, graf
Article in English | LILACS | ID: biblio-1001092

ABSTRACT

Abstract Purpose: To develop a silicone alternative model of tissue suture simulation to be used in the teaching of surgical technique. Methods: Twelve alternative models of silicone for tissue suture simulation were manufactured and implemented as a tool for suture pattern training of undergraduate medical students of Universidade Federal do Amazonas. Forty-eight students participated in the research. The evaluation of the proposed model was done through a questionnaire using the Likert scale, in order to verify the student satisfaction index of the alternative resource and its performance as opposed to the model historically used in the discipline, which is to suture in cloths. Results: The alternative model showed satisfactory results, especially with respect to the structural aspect, such as, better perception of anatomical planes, handling and transport. About 89.58% of positive concordant responses demonstrating expressive approval for incorporation of a complementary form of the alternative methodological proposal of the discipline of surgical technique. Conclusions: The model developed for experimental simulation of tissue sutures has proved to be a fully feasible alternative method for the training of this surgical skill. It is a simple, reproducible and low-cost model.


Subject(s)
Humans , Silicones , Suture Techniques/education , Simulation Training/methods , Models, Anatomic , Students, Medical , Surveys and Questionnaires , Reproducibility of Results , Clinical Competence , Education, Medical, Undergraduate/methods , Education, Medical, Undergraduate/standards , Simulation Training/standards , Academic Performance
11.
J. vasc. bras ; 17(3)jul.-set. 2018. ilus
Article in English | LILACS | ID: biblio-915983

ABSTRACT

Bullet embolization of the arterial or venous systems is a rare complication of penetrating gunshot injuries. A 29-year­old man presented at the emergency department with a gunshot wound to the left arm, which had transfixed the arm and entered the thorax, with no exit wound. Initial radiographies showed a projectile in the upper left thigh. Contrast­enhanced tomography showed a pseudo-aneurysm of the descending thoracic aorta and the bullet inside the proximal left superficial femoral artery. Physical examination found diminished left pedal pulses, and the patient complained of left toe numbness. Endovascular thoracic aortic pseudoaneurysm repair was performed, sealing the descending aortic orifice with an endograft, and thromboembolectomy/bullet retrieval was carried out via a left femoral incision, both successfully. Considering that diagnosis of missile emboli depends on a high degree of suspicion, physicians who manage gunshot wound patients must be acutely aware of the possibility of intravascular bullet embolism


A embolia balística pelo sistema arterial ou venoso é uma complicação rara de ferimentos penetrantes por arma de fogo. Um homem de 29 anos se apresentou na emergência com um ferimento por arma de fogo no braço esquerdo, que transfixou o braço e atingiu o tórax, sem ferimento de saída. Radiografias iniciais mostraram o projétil na coxa superior esquerda. A tomografia contrastada mostrou um pseudoaneurisma da aorta torácica descendente e o projétil no interior da artéria femoral superficial proximal esquerda. Ao exame físico, o pulso pedioso esquerdo estava diminuído e o paciente referiu dormência no hálux esquerdo. Foi realizado o reparo endovascular da aorta torácica e a tromboembolectomia/retirada do projétil por incisão femoral esquerda, ambos bem-sucedidos. Considerando que o diagnóstico de embolia balística depende de um alto grau de suspeição, os médicos que manejam pacientes com ferimentos por arma de fogo devem estar atentos a essa possibilidade


Subject(s)
Humans , Male , Adult , Embolism , Femoral Artery , Wounds, Gunshot , Aneurysm, False/complications , Aneurysm, False/diagnosis , Aorta, Thoracic/injuries , Endovascular Procedures/methods , Femoral Artery/injuries , Lower Extremity , Radiography/methods , Thromboembolism/complications , Tomography/methods , Upper Extremity
13.
Interact Cardiovasc Thorac Surg ; 26(2): 196-201, 2018 02 01.
Article in English | MEDLINE | ID: mdl-29049608

ABSTRACT

OBJECTIVES: Despite research into protective pharmacological adjuncts, paraplegia persists as a dreaded complication after thoracic and thoracoabdominal aortic interventions. Reports on gender-related neurological outcomes after ischaemic and traumatic brain injuries have led to increased interest in hormonal neuroprotective effects and have generated other studies seeking to prove the neuroprotective effects of the therapeutic administration of 17ß-oestradiol and of progesterone. We hypothesised that acute administration of oestradiol or progesterone would prevent or attenuate spinal cord ischaemic injury induced by occlusion of the descending thoracic aorta. METHODS: Male rats were divided into groups receiving 280 µg/kg of 17ß-oestradiol or 4 mg/kg of progesterone or vehicle 30 min before transitory endovascular occlusion of the proximal descending thoracic aorta for 12 min. Hindlimb motor function was assessed by a functional grading scale (that of Basso, Beattie and Bresnahan) for 14 days after reperfusion. On the 14th day, a segment of the thoracolumbar spinal cord was harvested and prepared for histological and immunohistochemical analyses. RESULTS: There was significant impairment of the motor function of the hindlimb in the 3 study groups, with partial improvement noticed over time, but no difference was detected between the groups. On Day 1 of assessment, the 17ß-oestradiol group had a functional score of 9.8 (0.0-16.5); the progesterone group, a score of 0.0 (0-17.1) and the control group, a score of 6.5 (0-16.9); on the 14th day, the 17ß-oestradiol group had a functional score of 18.0 (4.4-19.4); the progesterone group had a score of 7.5 (0-18.5) and the control group had a score of 17.0 (0-19.9). Analysis of the grey matter showed that the number of viable neurons per section was not different between the study groups on the 14th day. Immunostaining of the spinal cord grey matter was also similar among the 3 groups. CONCLUSIONS: Acute administration of oestradiol or of progesterone 30 min before transitory occlusion of the proximal descending thoracic aorta of male rats could not prevent or attenuate spinal cord ischaemic injury based on an analysis of functional and histological outcomes.


Subject(s)
Estradiol/administration & dosage , Progesterone/administration & dosage , Reperfusion Injury/drug therapy , Spinal Cord Ischemia/drug therapy , Spinal Cord/pathology , Animals , Disease Models, Animal , Estrogens/administration & dosage , Infusions, Intravenous , Male , Progestins/administration & dosage , Rats , Rats, Wistar , Reperfusion Injury/complications , Spinal Cord Ischemia/etiology
14.
J Vasc Bras ; 17(3): 262-266, 2018.
Article in English | MEDLINE | ID: mdl-30643515

ABSTRACT

Bullet embolization of the arterial or venous systems is a rare complication of penetrating gunshot injuries. A 29-year-old man presented at the emergency department with a gunshot wound to the left arm, which had transfixed the arm and entered the thorax, with no exit wound. Initial radiographies showed a projectile in the upper left thigh. Contrast-enhanced tomography showed a pseudo-aneurysm of the descending thoracic aorta and the bullet inside the proximal left superficial femoral artery. Physical examination found diminished left pedal pulses, and the patient complained of left toe numbness. Endovascular thoracic aortic pseudoaneurysm repair was performed, sealing the descending aortic orifice with an endograft, and thromboembolectomy/bullet retrieval was carried out via a left femoral incision, both successfully. Considering that diagnosis of missile emboli depends on a high degree of suspicion, physicians who manage gunshot wound patients must be acutely aware of the possibility of intravascular bullet embolism.


A embolia balística pelo sistema arterial ou venoso é uma complicação rara de ferimentos penetrantes por arma de fogo. Um homem de 29 anos se apresentou na emergência com um ferimento por arma de fogo no braço esquerdo, que transfixou o braço e atingiu o tórax, sem ferimento de saída. Radiografias iniciais mostraram o projétil na coxa superior esquerda. A tomografia contrastada mostrou um pseudoaneurisma da aorta torácica descendente e o projétil no interior da artéria femoral superficial proximal esquerda. Ao exame físico, o pulso pedioso esquerdo estava diminuído e o paciente referiu dormência no hálux esquerdo. Foi realizado o reparo endovascular da aorta torácica e a tromboembolectomia/retirada do projétil por incisão femoral esquerda, ambos bem-sucedidos. Considerando que o diagnóstico de embolia balística depende de um alto grau de suspeição, os médicos que manejam pacientes com ferimentos por arma de fogo devem estar atentos a essa possibilidade.

16.
J. vasc. bras ; 14(2): 182-185, Apr.-June 2015. ilus
Article in Portuguese | LILACS | ID: lil-756474

ABSTRACT

As complicações locais de uma lesão arterial penetrante incluem hematoma, pseudoaneurisma e formação de fístula arteriovenosa. A artéria femoral profunda, por sua localização anatômica, é sede infrequente de lesões traumáticas. Relatamos um caso de paciente jovem, vítima de agressão por arma branca em face posterior de coxa, em que foi diagnosticada, tardiamente, lesão de ramo descendente da artéria femoral profunda, sendo então tratada com técnica endovascular. A revisão de literatura corrobora a raridade do caso, sendo a maioria dos casos de lesão traumática de artéria femoral profunda relatada como decorrente de complicação de procedimentos ortopédicos ou fraturas envolvendo o fêmur proximal.


The local complications of penetrating injuries involving arteries include hematoma, pseudoaneurysm and arteriovenous fistulas. Traumatic injuries to the deep femoral artery are uncommon because of its anatomic location. We report the case of a young male patient who was victim of a stab wound to the posterior thigh who was later diagnosed with an injury to the descending branch of the deep femoral artery and treated using endovascular techniques. A review of the literature confirmed the rarity of the case, since the majority of cases of traumatic injuries to the deep femoral artery that have been reported were due to complications during orthopedic procedures or fractures involving the proximal femur.


Subject(s)
Humans , Male , Young Adult , Embolization, Therapeutic/methods , Femoral Artery , Aneurysm, False/diagnosis , Aneurysm, False/therapy , Wounds, Penetrating/complications , Wounds, Penetrating/therapy , Arteriovenous Fistula/diagnosis , Arteriovenous Fistula/therapy , Angiography/methods , Femur/injuries , Hematoma , Endovascular Procedures/methods
17.
J. vasc. bras ; 14(1): 78-83, Jan-Mar/2015. graf
Article in English | LILACS | ID: lil-744458

ABSTRACT

Iliac vein compression syndrome is a clinical condition in which the right common iliac artery extrinsically compresses the left common iliac vein. The syndrome predominantly affects young women between their 2nd and 4th decades of life. In view of the syndrome's potential complications, it should be recognized/diagnosed and treated in symptomatic patients before it causes irreversible damage to patients' venous systems. Noninvasive methods, such as venous color Doppler US are reasonable screening methods, but angiotomography and magnetic resonance angiography are more reliable diagnostic tools and the method of choice for confirmation of diagnosis remains multi-plane phlebography with measurement of pressure gradients. Endovascular treatment (angioplasty with placement of self-expanding stents) is safe and effective and can replace open surgical reconstruction and/or anticoagulation alone...


A Síndrome de Compressão da Veia Ilíaca (SCVI) é uma situação clínica na qual a artéria ilíaca comum direita comprime extrinsecamente a veia ilíaca comum esquerda. Há uma predominância em mulheres jovens, entre a segunda e a quarta décadas de vida. Levando-se em consideração as complicações potenciais da síndrome, esta deve ser reconhecida/diagnosticada e tratada, em pacientes sintomáticos, antes que cause alterações irreversíveis no sistema venoso do paciente. Métodos não invasivos, como o US-Doppler colorido, quando realizados por examinadores experientes, são métodos de triagem razoáveis; porém, a angiotomografia e a angiorressonância são mais fidedignas. O método de escolha para a confirmação diagnóstica consiste na flebografia, em múltiplas incidências, com aferição de gradientes pressóricos. O tratamento endovascular (angioplastia com colocação de stent autoexpansível) é seguro e efetivo, podendo substituir a reconstrução cirúrgica aberta e/ou a anticoagulação isolada...


Subject(s)
Humans , Female , Adult , Venous Insufficiency/complications , May-Thurner Syndrome/diagnosis , May-Thurner Syndrome/epidemiology , May-Thurner Syndrome/therapy , Iliac Vein , Lower Extremity , Incidence , Prevalence , Tomography, X-Ray Computed/methods
18.
J. vasc. bras ; 12(4): 324-328, Oct-Dec/2013. graf
Article in English | LILACS | ID: lil-699147

ABSTRACT

Bullet embolism is a rare complication of penetrating gunshots. We present a case of a 24-year-old man with a gunshot wound in the left scapular area, with no exit wound. Abdominal X-rays and a computed tomography (CT) scan suggested that the bullet was located within the intra-abdominal topography (intrahepatic), but laparotomy revealed no intra-abdominal injuries. After surgery, a sequential CT scan showed that the bullet had migrated to the right internal iliac vein (IIV). Venography confirmed the diagnosis of right IIV embolism and the decision was taken to attempt snare retrieval of the bullet, which was unsuccessful. It was therefore decided to leave the missile impacted inside the right IIV and the patient was put on oral anticoagulation. The patient recovered and was event free at 6 months' follow up.


Embolia balística é uma complicação rara de ferimentos por arma de fogo. Apresentamos um caso de um homem de 24 anos, vítima de um ferimento por arma de fogo em hemitórax posterior esquerdo (região escapular), sem orifício de saída. Radiografias e tomografia computadorizada do abdome evidenciaram um projétil em topografia intra-abdominal (intra-hepática); no entanto, a laparotomia exploradora demonstrou ausência de lesões intra-abdominais. Após a cirurgia, novo exame tomográfico revelou a migração da bala para a região da veia ilíaca interna (VII) direita. Realizada uma flebografia, esta confirmou a migração do projétil para a VII direita; tentou-se retirar o projétil durante o procedimento, sem sucesso. Optou-se, então, por deixá-la impactada na VII direita e manter o paciente em anticoagulação oral. O paciente evoluiu sem intercorrências até o sexto mês de seguimento.


Subject(s)
Humans , Male , Young Adult , Wounds, Gunshot/diagnosis , Wounds, Gunshot/therapy , Iliac Vein/pathology , Radiography, Thoracic/instrumentation , Tomography, X-Ray Computed/nursing
19.
J. vasc. bras ; 12(3): 243-246, Jul-Sep/2013. graf
Article in English | LILACS | ID: lil-695190

ABSTRACT

Radiation-induced arteritis is a rare but well-known complication of radiotherapy. This report describes the case of a 34-year-old woman with uterine cervical cancer who was diagnosed with left iliofemoral deep vein thrombosis (DVT) 2 years after radiotherapy, and 2 months later, during the treatment of DVT with effective anticoagulation, developed an episode of acute arterial ischemia of the left lower limb secondary to a long subocclusive lesion of the external iliac artery. The patient was treated with angioplasty and stenting of the lesion and recovered uneventfully after the endovascular procedure.


A arterite induzida por radiação é uma rara mas bem documentada complicação da radioterapia. O presente relato descreve o caso de uma mulher de 34 anos, diagnosticada com neoplasia de colo do útero, a qual, dois anos após sessões de radioterapia desenvolveu trombose venosa profunda (TVP) iliofemoral esquerda; dois meses depois, durante tratamento para TVP com devida anticoagulação, a paciente apresentou quadro de insuficiência arterial aguda do membro inferior esquerdo secundária a uma longa lesão suboclusiva da artéria ilíaca externa. A paciente foi tratada com angioplastia transluminal percutânea e implantação de stent autoexpansível, recuperando-se sem intercorrências após o procedimento endovascular.


Subject(s)
Humans , Female , Adult , Arteritis/radiotherapy , Peripheral Vascular Diseases/complications , Venous Thrombosis/diagnosis , Angioplasty/methods , Lower Extremity/radiation effects , Endovascular Procedures/methods , Stents
20.
J. vasc. bras ; 12(1): 75-80, jan.-mar. 2013. ilus
Article in Portuguese | LILACS | ID: lil-670393

ABSTRACT

As fístulas aortocavais são entidades raras e de etiologia variada. Uma minoria é consequente a eventos pós-traumáticos. As manifestações clínicas, nesses casos, podem ser agudas ou tardias. As tardias manifestam-se dias, semanas ou anos após o trauma, principalmente como quadro de insuficiência cardíaca congestiva. O tratamento de tais fístulas pode ser realizado através do reparo direto por cirurgia aberta ou através da abordagem endovascular. Relatamos o caso de um paciente do sexo masculino, de 53 anos que apresentou, 27 anos após um ferimento por arma branca abdominal, sinais importantes de insuficiência cardíaca congestiva, manifestada como palpitações e dispneia, fibrilação atrial paroxística, além de pressão arterial divergente e sopro em epigástrio. A angiotomografia confirmou o diagnóstico de fístula aortocaval e procedeu-se ao tratamento endovascular para o selamento da fístula. O paciente, segundo acompanhamento após três meses, apresentou evolução satisfatória, com melhora significante do quadro e controle adequado da insuficiência cardíaca congestiva.


Aortocaval fistulas are rare entities with different etiologies. A minority of them are consequent to post-traumatic events. The clinic in these cases may be acute or delayed. The later manifest themselves days, weeks or years after the trauma mainly as congestive heart failure. Its treatment can be done by open surgery or endovascular approach. The present case it is a 53 year old man who presented, 27 years after a stab wound in the abdomen, important signs of congestive heart failure, manifested as palpitations and dyspnea, paroxysmal atrial fibrillation, besides of dissenting blood pressure and bruit in the epigastrium. Angiotomography confirmed the diagnosis of aorto-caval fistula and proceeded to endovascular treatment for fistula repair. The patient, according with control after three months, showed a satisfactory outcome, with significant improvement of the condition and appropriate control of heart failure.


Subject(s)
Humans , Male , Middle Aged , Wounds, Stab/surgery , Arteriovenous Fistula/surgery , Endovascular Procedures/rehabilitation , Angiography , Aorta, Abdominal , Dissection , Tomography, X-Ray Computed
SELECTION OF CITATIONS
SEARCH DETAIL
...