Subject(s)
Light , Thrombophlebitis/diagnostic imaging , Humans , Leg/blood supply , Radiography , RheologyABSTRACT
In this study we have investigated the relationship between plaque sonolucency and ipsilateral hemispheric symptoms in 116 patients at risk of cerebrovascular disease (75 symptomatic patients, 41 asymptomatic patients). Our results indicate that plaque sonolucency is significantly associated with the incidence of patient symptoms at presentation. Twice as many symptomatic vessels contained the predominantly sonolucent plaque types (types 1 and 2) compared to contralateral asymptomatic vessels (p = 0.039, odds ratio = 2.9). Vessel stenosis also had a significant association with patient symptoms. No significant interaction was shown between vessel stenosis and plaque sonolucency (p = 0.15, odds ratio = 1.0). A model using vessel stenosis and plaque echogenicity as independent variables showed that degree of vessel stenosis had a closer association with incidence of symptoms (p = 0.03, odds ratio = 1.04) than plaque type (p = 0.13, odds ratio = 0.51).
Subject(s)
Arteriosclerosis/diagnostic imaging , Carotid Stenosis/diagnostic imaging , Aged , Arteriosclerosis/complications , Arteriosclerosis/physiopathology , Blood Flow Velocity , Carotid Arteries/diagnostic imaging , Carotid Stenosis/complications , Carotid Stenosis/physiopathology , Cerebrovascular Disorders/etiology , Female , Humans , Male , Prospective Studies , Risk Factors , UltrasonographyABSTRACT
A case of aberrant right subclavian artery (RSA) aneurysm presenting solely with symptoms and signs of superior vena cava obstruction (the SVC syndrome) is described. The SVC syndrome is usually a consequence of mediastinal malignancy and only rarely due to compression by an arterial aneurysm.
Subject(s)
Aneurysm/complications , Subclavian Artery , Superior Vena Cava Syndrome/etiology , Aged , Constriction, Pathologic/diagnostic imaging , Constriction, Pathologic/etiology , Humans , Male , Subclavian Artery/diagnostic imaging , Subtraction Technique , Superior Vena Cava Syndrome/diagnostic imaging , Tomography, X-Ray ComputedABSTRACT
Two cases of Alexander's disease are described. One case of infantile onset died at the age of 6 months and the second case was of the juvenile type with onset at 2 years and death at 10 years. A clinical diagnosis of this disease is difficult since signs can vary according to the age of the patient. The severity of the pathological changes can also depend upon the age of onset of this disease, but they are restricted to the central nervous system. The Rosenthal fibre is the characteristic feature of Alexander's disease and we have examined for the first time its ultrastructure and immunocytochemical characteristics at the electron microscopical level and demonstrated coexpression of anti-glial fibrillary acidic protein and anti-ubiquitin antisera.
