ABSTRACT
The authors expose the results of a retrospective study concerning 135 cases of neoplasia diagnosed by their Department between 1983 and 1993. The patients' age, their sex, their consume of tobacco, their survival from the moment of the diagnosis have been considered in the study. Likewise the clinical instrumental researches and their reliability, the different incidence of the examined pathology in the first and in the second part of the period considered. It is emerged from the collected data, that also in our territory there is an increasing tendency in the incidence of lung neoplasia, a generally short survival after the diagnosis, a strong prevalence of smokers among those people affected from the disease, the difficulty of an early diagnosis due to scarce specificity of the commonest symptoms. The final auspicious is that a more incisive diligence in prevention and significant progresses in clinical pharmacological research may determine a notable reduction of the incidence of such a dramatic pathology.
Subject(s)
Lung Neoplasms/epidemiology , Smoking/adverse effects , Adult , Aged , Aged, 80 and over , Bronchoscopy , Female , Humans , Italy/epidemiology , Lung Neoplasms/diagnosis , Lung Neoplasms/etiology , Lung Neoplasms/therapy , Male , Mass Screening , Middle Aged , Prevalence , Radiography, Thoracic , Retrospective Studies , Survival RateABSTRACT
Subcutaneous injections of 10(6) acid-fast bacteria from human lepromatous tissue to hibernating ground squirrels (Citellus tridecemlineatus) is followed by generalized infection of the animals and spontaneous death. The number of mycobacteria is high in the skin of GS during winter and decreases during summer. Animals surviving the first hibernation period invariably die during the second. The number of microorganism in the visceral organs is low at all times. The system of infected hibernating GS is a valuable model for the experimental study of leprosy.
Subject(s)
Disease Models, Animal , Leprosy/microbiology , Mycobacterium leprae/growth & development , Sciuridae/microbiology , Animals , Female , Hibernation , Kidney/microbiology , Lung/microbiology , Male , Sciuridae/physiology , Skin/microbiology , Spleen/microbiologyABSTRACT
A diagnosis of poorly differentiated, nodular, lymphocytic malignant lymphoma was made in two brothers. One had been operated 10 years earlier for an adenocarcinoma of the descending colon. In addition, another brother had died from a primary tumor of the liver. Although a genetic factor is not proved, the case is suggestive.
