ABSTRACT
La afectación neurológica en la enfermedad de Behçet es poco frecuente, especialmente como comienzo de la enfermedad. Puede presentarse con alteraciones parenquimatosas o con daño de las estructuras vasculares en su forma extraparenquimatosa. Es excepcional que ambos tipos de manifestaciones coexistan en un mismo paciente. Presentamos el caso de una paciente de 32 años, con antecedentes de trombosis venosa profunda, que acudió a nuestro centro por cuadro de cefalea holocraneal, apatía, aftas orales y genitales. La resonancia magnética cerebral mostró lesiones de hiperseñal en ganglios de la base y sustancia blanca silviana, y el estudio vascular trombosis venosa de seno transverso izquierdo. Tras confirmarse el diagnóstico de enfermedad de Behçet con afectación cerebral intra y extraparenquimatosa, se inició tratamiento inmunosupresor y corticoideo con remisión de la sintomatología
Neurological involvement in Behçet's disease is rare, especially at the onset. It can present in the form of parenchymal changes or as damage to the vascular structures in its nonparenchymal form. The coexistence of both kinds of manifestations in the same patient is exceptional. We report the case of a 32-year-old patient with a history of deep venous thrombosis, who was being treated for holocranial headache, apathy, and oral and genital ulcers. Brain magnetic resonance imaging showed hyperintense lesions in the basal ganglia and white matter, and the vascular study evidenced venous thrombosis of the left transverse sinus. After confirming the diagnosis of Behçet's disease with parenchymal and nonparenchymal cerebral involvement, immunosuppressive and corticosteroid therapy was started, resulting in the remission of the symptoms
Subject(s)
Humans , Female , Adult , Behcet Syndrome/complications , Sinus Thrombosis, Intracranial/etiology , Venous Thrombosis/etiology , Behcet Syndrome/psychology , Magnetic Resonance Imaging , Sinus Thrombosis, Intracranial/diagnostic imagingABSTRACT
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Subject(s)
Humans , Male , Mycobacterium Infections/microbiology , Mycobacterium tuberculosis/isolation & purification , Drug Resistance/drug effects , Rifampin/administration & dosage , Mycobacterium Infections/diagnosis , Mycobacterium Infections/drug therapy , Mycobacterium tuberculosis/drug effects , Radiography, Thoracic , Middle AgedABSTRACT
Neurological involvement in Behçet's disease is rare, especially at the onset. It can present in the form of parenchymal changes or as damage to the vascular structures in its nonparenchymal form. The coexistence of both kinds of manifestations in the same patient is exceptional. We report the case of a 32-year-old patient with a history of deep venous thrombosis, who was being treated for holocranial headache, apathy, and oral and genital ulcers. Brain magnetic resonance imaging showed hyperintense lesions in the basal ganglia and white matter, and the vascular study evidenced venous thrombosis of the left transverse sinus. After confirming the diagnosis of Behçet's disease with parenchymal and nonparenchymal cerebral involvement, immunosuppressive and corticosteroid therapy was started, resulting in the remission of the symptoms.
Subject(s)
Behcet Syndrome/complications , Sinus Thrombosis, Intracranial/etiology , Venous Thrombosis/etiology , Adult , Behcet Syndrome/psychology , Female , Humans , Magnetic Resonance Imaging , Sinus Thrombosis, Intracranial/diagnostic imagingSubject(s)
Antibiotics, Antitubercular/pharmacology , Mycobacterium tuberculosis/drug effects , Rifampin/pharmacology , Antibiotics, Antitubercular/therapeutic use , Drug Resistance, Bacterial , Genotype , Humans , Male , Microbial Sensitivity Tests , Middle Aged , Mycobacterium tuberculosis/genetics , Phenotype , Rifampin/therapeutic use , Tuberculosis, Pulmonary/drug therapyABSTRACT
We report an unusual case of myopericarditis caused by Rickettsia sibirica mongolitimonae. Because of increasing reports of Rickettsia spp. as etiologic agents of acute myopericarditis and the ease and success with which it was treated in the patient reported here, rickettsial infection should be included in the differential diagnosis for myopericarditis.