Static mandibular condyle positions studied by MRI and condylar position indicator.

We compared mandibular condyle positions as determined by magnetic resonance imaging (MRI) and a mechanical device, the condylar position indicator (CPI). Both methods assessed 3 mandibular positions in 10 asymptomatic males and 10 asymptomatic females, aged 23 to 37 years, free from temporomandibular disorders: maximum intercuspation, bimanually manipulated centric relation, and the unguided neuromuscular position. Bite registrations were obtained for bimanual operator guidance and neuromuscular position. 3 T MRI scans of both temporomandibular joints produced 3D data of the most superior condylar points in all 3 mandibular positions. Using mounted plaster casts and the same bite registrations, an electronic CPI displayed 3D data of its condylar spheres in these positions. The results showed interclass correlation coefficients ranging from 0.03 to 0.66 (95% confidence intervals from 0 to 0.8) and significantly different condyle positions between both methods (p = 0.0012, p < 0.001). The implications of the study emphasize that condyle position is unpredictable and variable. Its exact knowledge requires radiological imaging and should not rely on CPI assessments.

Angular changes in implants placed in the anterior maxillae of adults: a cephalometric pilot study.

OBJECTIVES: Completion of adolescent growth represents the earliest time point for implant placement, yet craniofacial growth persists into adulthood and may affect implant position. We aimed to assess whether implants placed in the anterior maxillae of adults show angular changes over time. MATERIAL AND METHODS: We conducted a cephalometric pilot study in postpubertal patients with no growth disorders, skeletal malformations, or parafunctions. The patients received a single implant in the anterior maxilla and no orthodontic or orthognathic treatment afterwards. We measured angular changes of implants and central incisors on cephalograms taken immediately and after at least 5 years postoperatively with the Sella-Nasion line (SNL) and the nasal line (NL) as references. Changes in implant-SNL angles were the primary outcome. RESULTS: In 21 patients (30.2 ± 11.5 years at surgery) after a mean follow-up of 8.6 ± 1.3 years, implant-SNL angles and implant-NL angles changed in 81% and 57% of implants, respectively. Implant-SNL changes ranged from 3° counterclockwise to 4° clockwise and were more prevalent in males (100% vs. 58%) and patients under 30 at surgery (85% vs. 63%); mean absolute differences were larger in males (1.8 ± 1.0° vs. 1.3 ± 1.4°) and patients under 30 at surgery (1.5 ± 1.4° vs. 1.1 ± 1.4°). Incisor-SNL angles and incisor-NL angles changed in 89% and 32% of incisors, respectively. CONCLUSIONS: Implants placed in the anterior maxillae of adults show modest angular changes over time. CLINICAL RELEVANCE: Changes in implant angles have potential functional and esthetic consequences.

Estimated functional space of centric condyle positions in temporomandibular joints of asymptomatic individuals using MRI.

Magnetic resonance imaging (MRI) studies on centric condyle positions lack 3D comparisons of guided and unguided methods, which are used for accomplishing centric relation reference positions. The purpose of this study was to describe the space, in which mandibular condyles are placed in vivo by dental intercuspation, Dawson's bimanual manipulation, and neuromuscular position. Twenty asymptomatic individuals aged 23 to 37 years underwent separate bite registrations using bimanual manipulation and the unguided neuromuscular technique. Subsequent 3-Tesla MRI scans of both temporomandibular joints yielded 3D data of the most superior condylar points at maximum intercuspation and both centric relation positions. We found concentric condyle positions in maximum intercuspation but considerable variation of condyle position after bimanual manipulation and neuromuscular technique. Their 95% predictive confidence ellipses overlapped substantially and created a space of reference positions. Its smallest volume averaged 2 mm3 for a minimal convex hull (95% confidence interval 1.1-3.2) and 3.5 mm3 for a minimal ellipsoid hull (95% confidence interval 1.8-5.4). Visualized in vivo by MRI, condyle positions at bimanual manipulation and neuromuscular position were not predictable and showed substantial variation in asymptomatic subjects. Clinicians should be aware of the functional space and its effect on dental intercuspation.

Association of anterior and posterior occlusal planes with different Angle and skeletal classes in permanent dentitions : A lateral cephalometric radiograph study.

OBJECTIVES: Malocclusions affect about two-thirds of the population and orthodontic treatment is justified in 65% of these. However, the associations between anterior and posterior occlusal plane (AOP, POP) inclinations and Angle classification are lacking. PATIENTS AND METHODS: In a retrospective study, lateral cephalometric radiograph tracings of 230 previously untreated Caucasians, aged 13 to 49 years, yielded inclines of the bisector occlusal plane, AOP, and POP. All inclinations were referenced to the Sella-Nasion line and the Frankfort horizontal and were assigned to the Angle classification as well as skeletal groups (retrognathic, neutral, prognathic). Quantile regressions were calculated. RESULTS: In the skeletal groups the angles between Sella-Nasion line and both AOP and POP were significantly different between the groups (p < 0.01), showing steep inclines in skeletal class II and flat inclines in skeletal class III. The angles Frankfort horizontal-to-POP and Frankfort horizontal-to-AOP showed the same trends but only the latter differed significantly between the groups (p = 0.02). Among the Angle groups, AOP inclinations did not differ significantly for both reference planes whereas POP inclinations were significantly different (p = 0.01 to Frankfort horizontal, p = 0.02 to Sella-Nasion). Angle class I patients showed the flattest POP. CONCLUSION: Occlusal plane inclines, measured to Sella-Nasion, were more consistent than those referenced to Frankfort horizontal. Sella-Nasion related anterior and posterior occlusal plane inclinations were steep in skeletal class II and flat in skeletal class III patients over all quantiles. Using the Angle classification, anterior and posterior occlusal plane inclinations did not follow this principle.

Geometric morphometrics of different malocclusions in lateral skull radiographs.

BACKGROUND: To evaluate the role of craniofacial shape in malocclusion by application of geometric morphometrics to a set of two-dimensional landmarks and semilandmarks obtained from lateral skull radiographs. METHODS: Cephalometric radiograph tracings of 88 untreated Caucasians (age range 7-39 years) were assigned to four groups according to their occlusion: neutrocclusion, distocclusion, mesiocclusion, and anterior open bite. The geometric morphometric shape analysis incorporated 66 landmarks and semilandmarks, which underwent generalized Procrustes analysis, between-groups principal component analysis, thin-plate spline deformation grid visualization, permutation tests, and receiver operating characteristic curves. RESULTS: The position and shape of the mandible contributed to differences between the distocclusion and mesiocclusion groups, whereas the maxillary shape showed less variation. The growth-related shape alteration during adolescence was most pronounced in the mesiocclusion group and least pronounced in the neutrocclusion group. The open bite group was associated with an altered orientation of the mandibular body and the maxilla,  showed the most hyperdivergent maxillomandibular pattern but was not an own skeletal entity. Despite clear differences in mean shape across the four groups, the individual distribution of craniofacial shape overlapped between the groups without discrete clusters. CONCLUSIONS: Craniofacial shape was clearly associated with dental malocclusion and showed considerable variation. Geometric morphometrics was a powerful research tool but for diagnosing individual malocclusion standard cephalometric measurements including overjet and overbite were equally or more efficient than geometric morphometric descriptors.

Inter- and intraobserver variability in resonance frequency analysis of palatal implants--a technical note.

PURPOSE: To assess inter- and intraobserver variability in wireless resonance frequency analysis (RFA) stability measurements of palatal implants and to evaluate the influence of age, sex, time after implant insertion, and measurement direction on variability. MATERIALS AND METHODS: Three observers conducted wireless RFA stability measurements of palatal implants from 16 patients. Measurements were taken in anteroposterior and laterolateral directions and were repeated after 1 hour. RESULTS: Data showed a small interobserver variation (1.93) with intraobserver variation (1.77) as its largest component. Time after implantation showed a strong influence (P = .027) on the interobserver variation. CONCLUSIONS: The tested wireless RFA device can be considered a reliable instrument for measuring the stability of palatal implants. Multiple readings and observers could further improve measurement reliability.

Systematic review on self-ligating vs. conventional brackets: initial pain, number of visits, treatment time.

OBJECTIVE: Meta-analysis of differences between conventional and self-ligating brackets concerning pain during tooth movement, number of patient visits, total treatment duration, and ligation times. MATERIALS AND METHODS: Online search in Medline, Embase, and Central focused on randomized clinical trials and controlled clinical studies published between 1996 and 2012. RESULTS: Four studies on pain met our inclusion criteria, two on the number of appointments, two on overall treatment time but none on ligation times. Pain levels did not differ significantly between patients treated with conventional or self-ligating brackets after 4 h, 24 h, 3 and 7 days. The number of appointments and total treatment times revealed no significant differences between self-ligating and conventional brackets. CONCLUSION: The lack of significant overall effects apparent in this meta-analysis contradicts evidence-based statements on the advantages of self-ligating brackets over conventional ones regarding discomfort during initial orthodontic therapy, number of appointments, and total treatment time. Due to the limited number of studies included, further randomized controlled clinical trials are required to deliver more data and to substantiate evidence-based conclusions on differences between the two bracket types considering orthodontic pain, number of visits, treatment, and ligation times.

A prospective randomized split-mouth study on pain experience during chairside archwire manipulation in self-ligating and conventional brackets.

OBJECTIVE: To investigate patient discomfort during archwire engagement and disengagement in patients treated with self-ligating and conventional brackets using a split-mouth design. MATERIALS AND METHODS: Eighteen consecutive patients (15 female, 3 male; age: 22.2 ± 6.4 years) who requested treatment with fixed orthodontic appliances were randomly assigned for bonding with SmartClip self-ligating brackets on one side of the dentition and conventional standard edgewise brackets on the other. During the course of treatment, patients rated the discomfort experienced during every archwire engagement and disengagement using a numeric rating scale. Results were evaluated for round and rectangular nickel titanium and rectangular stainless steel, titanium molybdenum, and Elgiloy archwires. Patients also rated their overall experience retrospectively for both bracket systems. RESULTS: Regardless of archwire type, disengagement was rated as being significantly more painful on the SmartClip side (P  =  .027). For rigid, rectangular archwires, engagement and disengagement were rated as being significantly more painful on the SmartClip side (P  =  .031; P  =  .004). Retrospective ratings favored conventional brackets beyond ratings recorded during treatment. CONCLUSION: Engagement and disengagement of rigid rectangular archwires caused more pain with SmartClip self-ligating brackets than with conventional ones. Careful archwire manipulation and patience during full alignment are essential for limiting chairside pain. Low pain levels will help ensure treatment satisfaction and compliance.

Midline correction by asymmetric reciprocal torque: a pilot study.

OBJECTIVE: Can we correct dental midline discrepancies by systematic torque bends on all canines and premolars without extraction and mesiodistal tooth movement? PATIENTS AND METHODS: Eight orthodontic patients (4 males, 4 emales, mean age 31 years) presented a dental midline discrepancy of 2-4 mm, moderate deviation of the chin, no skeletal asymmetry, and a horizontal orientation of the occlusal plane in the frontal aspect. On the side where the mandible was shifted medially, asymmetric torque bends moved the antagonist canine and both premolar crowns buccally, while palatal crown torque was used on the maxillary canine and premolars on the other side. Lingual crown torque corrected the medially shifted canine and premolars in the mandibular dental arch, and buccal crown torque the laterally shifted lower canine and premolars. RESULTS: On average, torque effects altered the canine guidance by 6.5 ± 4.7°, the first premolar guidance by 7 ± 4.1°, and the second premolar guidance by 6.3 ± 3.7°. Correction of the dental midline shift averaged 1.6 ± 0.8 mm after the torque, and eliminated the midline discrepancy completely (n = 2) or partly (n = 6). CONCLUSION: In this pilot study, asymmetric reciprocal torque represented a treatment option for midline corrections of approximately 2-4 mm and improvement in the chin position without mesiodistal tooth movement or extraction.

Comparison of Japanese and European overbite depth indicator and antero-posterior dysplasia indicator values.

This study evaluated cephalometric differences between 113 Japanese (43 males and 70 females, aged 14.1 ± 5 years) and 106 European subjects (36 males and 70 females, aged 13.5 ± 7.3 years) using two compound angular measurements and their single components: the overbite depth indicator (ODI) for the assessment of vertical skeletal relationships and the antero-posterior dysplasia indicator (APDI) for an evaluation of sagittal dysgnathia. Both populations were assigned to groups representing Angle Classes I, II, and III, and an anterior open bite (AOB) group. Two sample t- and Wilcoxon signed-ranks tests were performed (P < 0.05). The ODI values showed no statistically significant differences between the Japanese and European samples. The Japanese sample showed a significantly smaller APDI but only in the Class II group. In the Japanese Class II and III subjects, the malocclusion patterns were more pronounced than those in the Caucasian sample (overbite, overjet, and APDI).

Miniscrews in orthodontic treatment: review and analysis of published clinical trials.

INTRODUCTION: A systematic review of effects related to patient, screw, surgery, and loading on the stability of miniscrews was conducted. METHODS: Reports of clinical trials published before September 2007 with at least 30 miniscrews were reviewed. Parameters examined were patient sex and age, location and method of screw placement, screw length and diameter, time, and amount of loading. RESULTS: Fourteen clinical trials included 452 patients and 1519 screws. The mean overall success rate was 83.8% + or - 7.4%. Patient sex showed no significant differences. In terms of age, 1 of 5 studies with patients over 30 years of age showed a significant difference (P <0.05). Screw diameters of 1 to 1.1 mm yielded significantly lower success rates than those of 1.5 to 2.3 mm. One study reported significantly lower success rates for 6-mm vs 8-mm long miniscrews (72% vs 90%). Screw placement with or without a surgical flap showed contradictory results between studies. Three studies showed significantly higher success rates for maxillary than for mandibular screws. Loading and healing period were not significant in the miniscrews' success rates. CONCLUSIONS: All 14 articles described success rates sufficient for orthodontic treatment. Placement protocols varied markedly. Screws under 8 mm in length and 1.2 mm in diameter should be avoided. Immediate or early loading up to 200 cN was adequate and showed no significant influence on screw stability.

Osseointegration of a subperiosteal anchoring device in the minipig mandible.

INTRODUCTION: Onplants serve as subperiosteal anchorage in the maxilla to facilitate tooth movement. We determined the applicability of onplants and the process of osseointegration in the mandible of minipigs. METHODS: Thirty-six onplants (OnPlants, Nobel Biocare USA, Yorba Linda, Calif) were positioned in 9 adult animals, 2 on each side. At 3, 6, and 12 weeks after surgery, 3 minipigs were killed. Undecalcified ground sections were evaluated histologically and histomorphometrically. RESULTS: Nineteen onplants were lost during the observation period. Newly formed bone per tissue volume was 7% +/- 5% (n = 4), 21% +/- 9% (n = 5), and 22% +/- 13% (n = 8) at the 3 observation times. The corresponding percentages of bone-to-implant contact were 15% +/- 22%, 30% +/- 27%, and 44% +/- 35%. The number of bone-to-implant contacts remained stable over time at 1.0 +/- 0.9 contacts per millimeter. The average lengths of bone-to-implant contacts were 0.2 +/- 0.1 mm, 0.3 +/- 0.2 mm, and 0.5 +/- 0.3 mm. CONCLUSIONS: These results showed a low survival rate of onplants in the mandible and that the early stage of healing is central to the process of osseointegration. Stable placement is a prerequisite for onplant survival in the mandible.

Sagittal and vertical load-deflection and permanent deformation of transpalatal arches connected with palatal implants: an in-vitro study.

INTRODUCTION: The purposes of this laboratory investigation were to (1) measure the sagittal and vertical deflection of loaded transpalatal arches (TPAs) connected to a palatal implant, (2) measure the extent of permanent deformation of the connecting TPA in the sagittal and vertical directions, (3) test various wire dimensions in terms of deflection behavior, and (4) evaluate soldering vs laser welding vs adhesive bonding of TPAs in terms of load deflection behavior. METHODS: Stainless steel wires of 6 dimensions were tested: 0.8 x 0.8, 0.9, 1, 1.1, 1.2, and 1.2 x 1.2 mm. For each dimension, 10 specimens were soldered to the palatal implant abutment, 10 were laser welded, and 10 were adhesively bonded to the implant abutment (total, 180 specimens). The measuring device applied increments of force of 50 cN, from 0 to 500 cN. Then the specimens were unloaded. The values were statistically described and analyzed with ANOVA and Wilcoxon rank sum tests. RESULTS AND CONCLUSIONS: Absolute orthodontic anchorage without deformation of TPAs was not observed with the wire dimensions tested. To prevent loss of anchorage greater than 370 mum (sagittal deflection of 1.2 x 1.2 mm adhesively bonded TPA at 500 cN force level), wires thicker than 1.2 x 1.2 mm or cast anchorage elements must be considered for clinical practice. However, larger cross sections might cause more patient discomfort, and laboratory procedures increase costs.

Ninety percent success in palatal implants loaded 1 week after placement: a clinical evaluation by resonance frequency analysis.

To investigate the behaviour of early loaded palatal implants when observed with resonance frequency analysis (RFA). Twenty patients (seven males and 13 females, mean age 26.4 years) received one palatal implant each (length: 4 mm, diameter: 3.3 mm; Orthosystem) for maximum orthodontic anchorage. The implants' stability was observed by RFA. Measurements were carried out at the time of surgery, after first orthodontic loading and subsequently once a week over a period of 12 weeks. Two palatal implants were lost. The other 18 remained stable. The average period from insertion to first loading was 6.7+/-0.8 days. The mean orthodontic force applied was 272.2+/-73.2 cN. The implant stability quotient (ISQ) value at the time of surgery averaged 69.4+/-3.9. The mean ISQ value 6.7 days after insertion was 69.8+/-3.6. Twelve weeks post-surgery the mean ISQ value was 69.8+/-3.5. A statistically significant decrease in stability was observed after 2 and 3 weeks post-surgery (P=0.005 and 0.04). The behaviour of early loaded palatal implants showed an initial decrease of the ISQ values. From 6 weeks post-surgery onward the ISQ values increased. Within the limitations of this study, the results suggest that the healing time of palatal implants reported in the literature (12 weeks) should be discussed. An orthodontic loading of palatal implants 6 weeks post-surgery with a force up to 400 cN seems to be justified. Yet further investigations are necessary to evaluate the behaviour of early loaded palatal implants considering observation periods of over 12 weeks.

Novel development for intraoral distraction osteogenesis by individually fabricated traction prostheses.

Modified fixed or removable partial dentures are used for intraoral distraction osteogenesis. These traction prostheses rest on teeth or endosseous implants and direct distraction forces to an endosseous implant in the osteotomy segment. This article explains the fabrication and function of custom-made traction prostheses for 1-, 2- and 3-dimensional distraction osteogenesis.

Use of an individual traction prosthesis and distraction osteogenesis to reposition osseointegrated implants in a juvenile with ectodermal dysplasia: a clinical report.

This article describes the use of distraction osteogenesis to reposition osseointegrated maxillary implants in an adolescent girl with ectodermal dysplasia and oligodontia. The distraction of 2 osteotomized segments was controlled by a prosthesis fabricated specifically for this purpose.