Pigmented basal cell carcinomas in Gorlin syndrome: two cases with different dermatoscopic patterns.

We describe two nonconsanguineous white patients with multiple pigmented basal cell carcinomas (BCCs) that were histopathologically confirmed. The first patient had calcification of the cerebral falx, multiple keratocysts in the jaw, and other malformations of the cranial and finger bones. The second patient presented with multiple dermoid cysts, calcification of the cerebral falx, keratocysts of the mandible, and agenesis of left kidney. Both patients had palmar pits. Both denied any family history of cutaneous tumours. On dermatoscopic examination of patient 1, multiple, bluish, confluent and large globules were seen. The second patient had blue ovoid globules, arborizing vessels, and areas shaped like maple leaves and spoke-wheels. Based on the clinical and radiological features we diagnosed both patients as having Gorlin syndrome (GS). To our knowledge, there are no previous reports of white patients with GS showing only pigmented BCCs. The dermatoscopic patterns were different in the two patients, and to our knowledge, this is the first report of a patient with GS showing a spoked-wheel dermatoscopic pattern.

Load transmission evaluation by removable distal-extension partial dentures using holographic interferometry.

Five pairs of bilateral distal-extension removable partial dentures with different clasp designs were constructed on the same dried human mandible in order to compare their load distribution characteristics. The technique of holographic interferometry was used. Among the dentures tested, those with RPI and back action clasps having mesial rests provided the best results from the mechanical point of view. The most unfavourable behaviour was presented by the Akers clasps design. The RPA design and dentures having clasps with continuous MOD rest gave intermediate results.