ABSTRACT
Neck mass can be an initial finding of many diseases at any age. The differential diagnosis is broad and includes inflammatory, congenital and neoplastic lesions. We retrospectively analyzed charts of the 145 patients with neck mass and without known primary malignancy whose diagnoses were confirmed with histopathologic and serologic examination between July 2003 and July 2008. Twenty-six patients (17.9%) were diagnosed with tularemia. Before 2004, serologic testing for tularemia was not a part of our workup for patients with an inflammatory neck mass. Otolaryngologists should be familiar with head and neck manifestations of tularemia and consider the disease in the differential diagnosis of neck masses. The tularemia outbreak in central Black Sea region, Turkey in 2004 changed our approach to a patient presenting with neck mass.
Subject(s)
Abscess/diagnosis , Disease Outbreaks , Lymphatic Diseases/diagnosis , Neck , Otorhinolaryngologic Diseases/diagnosis , Tularemia/diagnosis , Abscess/epidemiology , Abscess/pathology , Adult , Biopsy , Cross-Sectional Studies , Delayed Diagnosis , Diagnosis, Differential , Endoscopy , Female , Humans , Lymphatic Diseases/epidemiology , Lymphatic Diseases/pathology , Male , Middle Aged , Otorhinolaryngologic Diseases/epidemiology , Otorhinolaryngologic Diseases/pathology , Retrospective Studies , Tularemia/epidemiology , Tularemia/pathology , Turkey , Young AdultABSTRACT
OBJECTIVE: We aimed to elucidate the effects of exogenous nitric oxide application via myrigotomized rat tympanic membranes on tympanosclerosis. MATERIALS AND METHODS: Forty male rats were included in the study. After myringotomy, nitric oxide was given to the left tympanic cavities and saline was given to the right as the control group. The procedure was repeated 3 times with weekly intervals. Three months after the first procedure, otomicroscopic examination was made and the rats were sacrificed for histologic examination. RESULTS: Neither otomicroscopic examination, nor histologic examination of middle ears and tympanic membranes revealed any significant difference between the right and left sides. Tympanic membrane thicknesses were also similar on both sides without showing any significant difference. CONCLUSIONS: Data from this study indicate that exogenous nitric oxide application did not change the occurence of tympanosclerosis in the rat model. Other cytokine interactions are needed to start the reaction sequence leading to tympanosclerosis.
Subject(s)
Nitric Oxide Donors/pharmacology , Otosclerosis/drug therapy , Otosclerosis/pathology , Triazenes/pharmacology , Tympanic Membrane/pathology , Animals , Disease Models, Animal , Ear, Middle/drug effects , Ear, Middle/pathology , Male , Microscopy , Rats , Rats, Sprague-Dawley , Tympanic Membrane/drug effects , Tympanic Membrane/surgerySubject(s)
Atrial Fibrillation/diagnosis , Heart Atria/physiopathology , Mitral Valve Stenosis/diagnosis , Rheumatic Heart Disease/diagnosis , Vocal Cord Paralysis/diagnosis , Atrial Fibrillation/diagnostic imaging , Atrial Fibrillation/etiology , Dyspnea/etiology , Echocardiography , Female , Heart Atria/surgery , Heart Valve Prosthesis Implantation , Hoarseness/etiology , Humans , Laryngoscopy , Middle Aged , Mitral Valve Stenosis/complications , Mitral Valve Stenosis/surgery , Rheumatic Heart Disease/complications , Rheumatic Heart Disease/surgery , Syndrome , Vocal Cord Paralysis/etiologyABSTRACT
Pneumolabyrinth can result from traumatic luxation of stapes into the vestibule. The diagnosis of stapes luxation following a head injury can be delayed especially if the otoscopic examination is within normal limits. Here a 15-year-old girl presenting with vertigo and nystagmus following a blunt head injury was presented, whose computerized tomography revealed air in the vestibule and cochlea (pneumolabyrinth) and stapes was found to be luxated into the vestibule.
