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Eur J Epidemiol ; 19(2): 189-93, 2004.
Article in English | MEDLINE | ID: mdl-15074575

ABSTRACT

Paracoccidiodomycosis and histoplasmosis are endemic diseases in the south of Venezuela, representing a public health problem. Prevalence of Paracoccidiodes brasiliensis and Histoplasma capsulatum infections were estimated in Monte Ralo, a rural community area of Bolivar state using paracoccidiodine and histoplasmine skin tests. Paracoccidiodine was intradermically injected to 173 persons and readings were made at 24 and 48 h afterwards to 167 persons (97.85%). Reaction was positive in 8.5% (n = 14) at 24 h post-injection and 13.2% (n = 20) at 48 h. Farmers showed the higher percentage of positivity at 24 and 48 h. One hundred-seventy five persons were intradermically injected with histoplasmine but 167 and 157 of them attended for reading of the dermal reaction at 24 and 48 h post-injection respectively. Tests were positive in 25.7% (n = 43) at 24 h and 42.7% (n = 67) at 48 h. Further studies are needed in surrounding places to delimit the endemic area of these mycosis in the Bolivar state. However, epidemiological vigilance of PCM and H should be considered by local health authorities.


Subject(s)
Coccidioidin/adverse effects , Histoplasmin/adverse effects , Histoplasmosis/epidemiology , Paracoccidioidomycosis/epidemiology , Adolescent , Adult , Age Distribution , Child , Child, Preschool , Coccidioidin/pharmacology , Endemic Diseases , Female , Histoplasmin/pharmacology , Histoplasmosis/diagnosis , Humans , Incidence , Male , Middle Aged , Paracoccidioidomycosis/diagnosis , Population Surveillance , Risk Factors , Rural Population , Sex Distribution , Skin Tests/methods , Venezuela/epidemiology
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