ABSTRACT
BACKGROUND: Gastrointestinal stromal tumors (GISTs) are low-grade malignant tumors that may arise anywhere in the alimentary tract, and in the past, most of them were diagnosed as intestinal leiomyoma or leiomyosarcoma. GISTs of the duodenum make up only 4.5% of all GISTs. MATERIALS AND METHODS: We report a patient presented with upper GI bleeding who exhibited radiological findings of a tumor in the third portion of the duodenum. The patient underwent a segmental duodenectomy. Pathological examination concluded in a GIST. RESULTS: The patient is free of recurrence for one year after surgery. CONCLUSIONS: Our case report, along with other, highlights that surgical resection remains the cornerstone of treatment for patients with localized disease. Along with others, we agree that from oncologic point of view, partial resection of the duodenum is an alternative to a duodenopancreatectomy.
Subject(s)
Duodenal Neoplasms/pathology , Gastrointestinal Stromal Tumors/pathology , Duodenal Neoplasms/diagnostic imaging , Gastrointestinal Stromal Tumors/diagnostic imaging , Humans , Immunohistochemistry , Male , Middle Aged , Tomography, X-Ray ComputedABSTRACT
Duodenal endocrine tumors are rare and represent 2% of all gastrointestinal endocrine neoplasms. Carcinoids of the ampulla of Vater are the most rare primary ampullary tumors. There was noted a frequent association of the endocrine tumors with type 1 neurofibromatosis also known as von Recklinghausen disease. To the best of our knowledge there are only 8 cases of papilla duodenalis minor carcinoids described in the literature. Authors describe herein the first carcinoid of papilla duodenalis minor case associated with multiple synchronic jejunal leiomyomas and von Recklinghausen disease, manifested with proximal intestinal obstruction and resolved by pancreatoduodenectomy (Kausch-Whipple procedure).
