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1.
Transplant Proc ; 42(1): 324-7, 2010.
Article in English | MEDLINE | ID: mdl-20172342

ABSTRACT

The increasing number of heart transplant recipients receiving immunosuppression with mammalian target of rapamycin inhibitors prompted the implementation of a South American Transplant Physicians Group to register these patients in a database. Everolimus (EVL) is a signal proliferation inhibition that reduces graft vascular disease when used de novo. Recently, its administration has expanded to subjects with resistant rejection or with side effects due to other immunosuppressive drugs (calcineurin inhibitors and/or steroids), allowing for better regulation of the immunosuppressive regimen. Herein we have shown the data collected from patients receiving EVL in ten South American Heart Transplant Centers. We have concluded that the administration of EVL is a useful adjunctive therapy that allows the reduction or suspension of other immunosuppressive drugs that caused unwanted side effects, without a loss of immunosuppressive efficacy, with manageable side effects, and constituting a valuable therapeutic option.


Subject(s)
Heart Transplantation/immunology , Heart Transplantation/statistics & numerical data , Immunosuppressive Agents/therapeutic use , Registries/statistics & numerical data , Sirolimus/analogs & derivatives , Adolescent , Adrenal Cortex Hormones/adverse effects , Adrenal Cortex Hormones/therapeutic use , Adult , Aged , Child , Cyclosporine/therapeutic use , Everolimus , Female , Heart Transplantation/adverse effects , Humans , Immunosuppressive Agents/adverse effects , Male , Middle Aged , Sirolimus/therapeutic use , South America , Tacrolimus/therapeutic use
2.
Rev. chil. urol ; 62(2): 183-5, 1997. graf
Article in Spanish | LILACS | ID: lil-216350

ABSTRACT

Desde el año 1995 hemos incorporado la VPTU dentro de los métodos para el tratamiento de la HPB. Se seleccionaron 44 pacientes con sintomatología obstructiva prostática severa, estudiando su score (IPSS), Q. máxima, volúmen prostático, tiempo operatorio y complicaciones. La operación se efectuó complementada con cistostomía percutánea. El score promedio, disminuyó de 21,1 a 7,4 a los 3 meses después de la cirugía. El Q. máximo, aumentó de 4,5 ml/seg. a 12,9 ml/seg. No hubo complicaciones de importancia y no se produjo ningún caso de incontinencia ni de impotencia relacionada con el procedimiento. En nuestra experiencia, la VPTU está demostrando ser un método eficiente y seguro para el tratamiento de la HPB


Subject(s)
Humans , Male , Middle Aged , Prostatic Diseases/surgery , Prostatic Hyperplasia/surgery , Therapeutic Irrigation , Cystostomy , Hematuria
3.
Arch. pediatr. Urug ; 53(3): 135-40 passim, 1982.
Article in Spanish | LILACS | ID: lil-12473

ABSTRACT

Se analizan factores asociados al tipo de presentacion fetal en una muestra de 420 recien nacidos (RN), 105 correspondientes a presentacion podalica (PP) y 135 a presentacion cefalica; un total de 2960 nacimientos en el periodo 1/10/79 al 31/3/80.La distribucion segun procedencia, edad y paridad materna y sexo del RN es similar.El grupo de RN en PP se asocia significativamente con la falta de control de las gestantes y rotura prematura de membranas; observandose un predominio de RN prematuros; pequenos para la edad gestacional; mayor depresion, patologia y mortalidad, constituyendo un problema medico social de interes


Subject(s)
Pregnancy , Infant, Newborn , Humans , Female , Breech Presentation , Morbidity , Mortality , Maternal Age , Prenatal Care
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