ABSTRACT
The development of perianal ulcers related to the use of a hemorrhoidal ointment has not been reported in the literature. We describe a series of 11 patients who were treated for perianal ulcers in 10 Spanish hospitals after they used the same ointment containing the active ingredients triamcinolone acetonide, lidocaine, and pentosan polysulfate sodium. No prior or concomitant conditions suggesting an alternative cause for the condition could be identified, and after the patients stopped using the ointment, their ulcers cleared completely in 8 weeks on average. This case series shows the damage that can be caused by an over-the-counter pharmaceutical product used without medical follow-up. It also illustrates the need to ask patients with perianal ulcers about any topical agents used before the lesions appeared.
ABSTRACT
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Subject(s)
Humans , Female , Adult , Dermatitis, Allergic Contact/diagnosis , Additives in Cosmetics , Cosmetics/adverse effects , Hypersensitivity, Immediate/complicationsSubject(s)
Dermatitis, Occupational/etiology , Skin Cream , Thiazoles/adverse effects , Adult , Drug Contamination , Female , HumansSubject(s)
Nevus, Epithelioid and Spindle Cell/pathology , Skin Neoplasms/pathology , Child , Humans , MaleABSTRACT
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Subject(s)
Humans , Female , Aged , Keratosis/diagnosis , Hand , Calcinosis/diagnosisABSTRACT
The treatment of acute generalized pustular psoriasis has classically been carried out with oral retinoids, cyclosporine, methotrexate, dapsone,colchicine, corticoids, coal tar or PUVA, slow and partial responses, as well as recurrences when the medication is decreased or suspended, being veryrelatively frequent. Several cases of acute generalized pustular psoriasis treated with infliximab and with quick and effective responses have recentlybeen published based on the physiopathological relationship between the tumor necrosis factor (TNF) and psoriasis (AU)
El tratamiento de la psoriasis pustulosa generalizada aguda se ha venido realizando con retinoides orales, ciclosporina, metotrexato, dapsona, colchicina,corticoides, coal tar o PUVA, siendo relativamente frecuentes las respuestas parciales o lentas, así como las recurrencias cuando la medicación sereduce o suspende.Receintemente se han publicado varios casos de psoriasis pustulosa aguda gerneralizada tratadas con infliximab y con respuestas rápidas y eficacesbasadas en la relación entre el factor de necrosis tumoral (TNF) y la psoriasis (AU)
Subject(s)
Humans , Female , Middle Aged , Psoriasis/diagnosis , Psoriasis/drug therapy , Psoriasis/etiology , Psoriasis/pathology , Psoriasis/chemically induced , Schizophrenia/complications , Tumor Necrosis Factors/antagonists & inhibitorsABSTRACT
La hiperplasia angiolinfoide con eosinofilia (HALE) es una enfermedad infrecuente, tumoral o reactiva, caracterizada por lesiones angiomatosas solitariaso múltiples que suelen localizarse en el cuero cabelludo y la cara. Los hallazgos histológicos consisten en una proliferación vascular con célulasendoteliales prominentes y un infiltrado intersticial crónico de células inflamatorias, principalmente eosinófilos. Presentamos un nuevo caso de HALE yrevisamos la literatura publicada en revistas españolas (AU)
Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon disease, tumoral or reactive, characterized by single or multiple angiomatouslesions usually localized on the scalp and face. The histologic features consist of proliferation of blood vessels with prominent endothelial cells andinfiltration of the interstitium by chronic inflammatory cells, mainly eosinophils.We report a new case of ALHE and review the literature published in Spanish journals (AU)
Subject(s)
Humans , Female , Middle Aged , Angiolymphoid Hyperplasia with Eosinophilia/pathology , Remission, SpontaneousABSTRACT
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