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1.
Mil Med ; 188(11-12): 3295-3301, 2023 11 03.
Article in English | MEDLINE | ID: mdl-37522358

ABSTRACT

INTRODUCTION: There is no cure for tinnitus, which is a highly prevalent condition in service members and veterans. Battlefield acupuncture (BFA) can be used to manage pain and stress-related symptoms. We investigated BFA as a safe, low-cost treatment for tinnitus perception and coping in eight chronic tinnitus patients who were followed for 6 months after two BFA treatments to identify changes in tinnitus severity or impact. MATERIALS AND METHODS: Patients completed case history, Tinnitus Screener, Tinnitus Functional Index (TFI), Tinnitus Reaction Questionnaire (TRQ), and Hospital Anxiety and Depression Scale (HADS) questionnaires at baseline, at two BFA treatment sessions (2 weeks apart), and at four follow-up sessions (at 1, 2, 4 and 6 months after treatment). Questionnaire score changes were evaluated over time by using restricted maximum likelihood hierarchical regression modeling from baseline to 1-, 2-, 4-, and 6-month post-treatment follow-ups. RESULTS: TFI and TRQ group means were both significantly reduced at 1 month after treatment, and these reductions persisted through the 2- and 4-month follow-ups. The TRQ group mean remained significantly reduced after 6 months. CONCLUSIONS: Findings from eight chronic tinnitus sufferers who received two BFA treatment sessions are reported here, suggesting at least short-term treatment benefits observed as reductions in tinnitus-related psychological distress and impact. Although these findings are constrained by the study's small sample size and limited treatment period, its findings underscore the need for further research to determine the potential benefits of BFA for individuals who suffer from chronic tinnitus. Future research should consider the possibility of more lasting benefits through extended BFA treatment, with a comparison of BFA treatment against other treatment methods.


Subject(s)
Acupuncture Therapy , Tinnitus , Veterans , Humans , Tinnitus/therapy , Tinnitus/diagnosis , Pilot Projects , Acupuncture Therapy/methods , Adaptation, Psychological
2.
J Stud Alcohol Drugs ; 73(2): 195-204, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22333327

ABSTRACT

OBJECTIVE: This article presents the first direct comparison of level of response (LR)-based prospective models in two generations of the same families. To accomplish this, we describe results from the first prospective evaluation of potential mediators of how an earlier low LR to alcohol relates to adverse alcohol outcomes in offspring from the San Diego Prospective Study (SDPS). METHOD: To compare with data from probands in the SDPS, new data were gathered from 86 drinking offspring (age ~20 years) during the 25-year follow-up of these families. Consistent with the usual effect of a low LR, outcomes 5 years later for both generations focused on drinking quantities as well as alcohol problems during the follow-up. A structural equation model (SEM) was used to analyze the relationships among variables, and the models in proband and offspring generations were compared using direct observations of the model results and through invariance procedures. RESULTS: In these drinking offspring, LR correlated with 5-year outcomes (r = .48, p < .001) and the SEM R² was .48, with good fit statistics. As predicted, the LR relationship to alcohol-related outcomes was both direct and partially mediated by heavier peer drinking, positive alcohol expectancies, and using alcohol to cope with stress. These results were similar to a previously published prospective model in SDPS probands, although path coefficients were generally higher in the younger group. CONCLUSIONS: The LR-based model of heavier drinking operated similarly across generations, with some modest differences. These results indicate that the model may be meaningful in both younger and middle-age groups.


Subject(s)
Alcohol Drinking/epidemiology , Alcoholism/epidemiology , Ethanol/pharmacology , Adult , Age Factors , Alcohol Drinking/blood , Alcoholism/blood , Ethanol/blood , Family Health , Female , Humans , Male , Models, Psychological , Prospective Studies , Risk Factors , United States/epidemiology
3.
Am J Drug Alcohol Abuse ; 37(6): 479-86, 2011 Nov.
Article in English | MEDLINE | ID: mdl-21797810

ABSTRACT

BACKGROUND AND OBJECTIVES: Evaluations of how a genetically influenced characteristic, such as the low level of response (a low LR) to alcohol, relates to later heavy drinking and alcohol problems usually include environmental contributors. The best way to understand how LR works in the context of these additional characteristics is to study the process prospectively, but such analyses tend to be complex and the papers are sometimes cluttered with jargon. This report attempts to offer a more straightforward description of the results from such a prospective model of how a lower LR at age 20 relates to alcohol outcomes at age 40. METHODS: A structural equation model of LR at age ∼20, outcomes of heavy drinking and problems at age ∼40, and additional characteristics at age ∼35 were tested in 378 men from the San Diego Prospective Study. RESULTS: The results support both direct effects of age-20 LR on age-40 heavy drinking and alcohol problems, as well as indirect effects of LR through characteristics of these men at age 35. The latter include using alcohol to cope with stress and heavier drinking among peers. CONCLUSIONS: A low LR to alcohol is an example of how both genes and environment can contribute to the risk for adverse alcohol outcomes. The identification of mechanisms through which LR impacts on later heavy drinking and problems can be approached in cross-sectional studies, but those may not be as sensitive as longitudinal models for identifying additional potential mediators of the LR-to-outcome relationship.


Subject(s)
Alcohol Drinking/epidemiology , Alcohol-Related Disorders/epidemiology , Models, Statistical , Stress, Psychological/complications , Adult , Alcohol Drinking/genetics , Alcohol Drinking/psychology , Alcohol-Related Disorders/genetics , Alcohol-Related Disorders/psychology , California , Follow-Up Studies , Genetic Predisposition to Disease , Humans , Longitudinal Studies , Male , Peer Group , Prospective Studies , Social Environment , Young Adult
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