ABSTRACT
Fourteen patients affected by endometriosis were treated by Danazol and by Goserelin. The two treatments were compared. From the study it emerged that both treatments were equally effective; however, the analogs gave a more favourable therapeutic profile.
Subject(s)
Buserelin/analogs & derivatives , Danazol/therapeutic use , Endometriosis/drug therapy , Pelvic Neoplasms/drug therapy , Bone Density , Buserelin/adverse effects , Buserelin/therapeutic use , Danazol/adverse effects , Female , Goserelin , HumansABSTRACT
Therapy with GnRH analogs is the first medical solution to be really effective in treating uterine fibromas, even if with limited and temporary benefits. Out of the 12 patients treated the Authors observed that a 60% reduction of the volume of the uterus can be achieved after 3-6 months therapy, with rapid recuperation of the initial volume after interruption of the treatment. It is therefore preferable to use GnRH analogs as a propedeutic therapy rather than surgery.
Subject(s)
Buserelin/analogs & derivatives , Leiomyoma/drug therapy , Uterine Neoplasms/drug therapy , Adult , Buserelin/administration & dosage , Buserelin/adverse effects , Buserelin/therapeutic use , Delayed-Action Preparations , Female , Goserelin , Hemoglobins/analysis , Humans , Leiomyoma/diagnostic imaging , Middle Aged , Pregnancy , Remission Induction , Ultrasonography , Uterine Neoplasms/diagnostic imagingSubject(s)
Antifungal Agents/therapeutic use , Candidiasis, Vulvovaginal/drug therapy , Imidazoles/therapeutic use , Adolescent , Adult , Female , Humans , Male , Middle AgedABSTRACT
On the basis of two interesting observations of toxoplasmic disease the Authors attempt to interpret the various pathological pictures, comparing two different formulations of toxoplasmic disease: that of Sabin and that of more modern AA.
Subject(s)
Pregnancy Complications, Infectious/immunology , Toxoplasmosis, Ocular/immunology , Abortion, Habitual/etiology , Adult , Antibodies/analysis , Female , Humans , Placenta Diseases/pathology , Pregnancy , Pregnancy Complications, Infectious/pathology , Toxoplasmosis/pathology , Toxoplasmosis, Ocular/pathologySubject(s)
Labor, Induced , Labor, Obstetric , Adult , Age Factors , Birth Weight , Delivery, Obstetric/methods , Female , Gestational Age , Humans , Infant, Newborn , Oxytocin/administration & dosage , Parity , PregnancyABSTRACT
In a previous study ten women with hyperprolactinemia and amenorrhea had significantly higher Symptom Questionnaire scores for depression, hostility and anxiety than patients with amenorrhea only and a matched nonpatient employees group. The hyperprolactinemic patients and employees were compared with ten women on their seventh day after childbirth who had been matched for sociodemographic variables and had similar prolactin levels. Hostility was significantly higher in postpartum patients than employees and did not differ significantly from that of women with hyperprolactinemic amenorrhea. Postpartum hyperprolactinemic women did not differ significantly from the employees for anxiety and depression, which was significantly lower than in the amenorrheic patients. In several mammals aggression occurs concurrently with lactation. The studies in humans suggest an association of high prolactin levels with hostility.
