Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Publication year range
1.
Semina cienc. biol. saude ; 42(1): 81-90, jan./jun. 2021. Tab
Article in Portuguese | LILACS | ID: biblio-1247943

ABSTRACT

Objetivo: analisar a visão da enfermagem sobre o atendimento humanizado no setor de urgência e emergência e identificar fatores que dificultem esse processo. Material e Método: trata-se de um estudo descritivo, com abordagem quantitativa, realizado em uma instituição hospitalar privada localizada no Sul do Brasil. Os dados foram recolhidos através de questionários formulados por 20 perguntas, nos quais foram coletadas informações referentes à identificação do profissional como: gênero, faixa etária, escolaridade, materiais relativos ao conhecimento e visão da equipe em relação ao atendimento humanizado. Posteriormente, os materiais foram analisados e organizados em tabelas, os quais foram computados no programa SPSS® - Statistical Package for the Social Sciences (SPSS® 20). Resultados: considerando os critérios de inclusão e exclusão, a amostra foi composta por 16 questionários válidos. Os dados analisados evidenciaram que a equipe tem compreensão sobre o atendimento humanizado e desejo em adquirir mais conhecimento, porém há insatisfação devido à sobrecarga de trabalho ocasionada com a superlotação do serviço. Conclusão: a pesquisa comprovou que os profissionais enfrentam dificuldades durante sua jornada de trabalho devido à alta demanda de atendimentos, evidenciando-se, assim, a necessidade da administração de estratégias para situações de fluxo intenso e a carência de profissionais para o setor de urgência e emergência.(AU)


Objective: to analyze the nursing vision on humanized attendance in the urgent and emergency sector and identify factors that make this process difficult. Material and Method: this is a descriptive study, with a quantitative approach, carried out in a private hospital institution located in the South of Brazil. The data were collected through a twenty-question questionnaire, inquiring information referring to the professional's identification such as gender, age group, schooling, materials related to the team's knowledge and vision concerning the humanized attendance. Later, the materials were analyzed and organized in tables, computed in the program SPSS® - Statistical Package for the Social Sciences (SPSS® 20). Results: considering the inclusion and exclusion criteria, the sample consisted of 16 valid questionnaires. The data analyzed showed that the team comprehends humanized care and desire to acquire more knowledge. However, they are dissatisfied with work overload caused by overcrowding. Conclusion: the research evidenced that professionals face difficulties during their working hours due to the high service demand. Hence, the need to manage intense flow situations and the lack of professionals for the urgent and emergency sector is evident.(AU)


Subject(s)
Humans , Vision, Ocular , Emergencies , Societies , Hospitals, Private
2.
Arch Pharm Res ; 35(10): 1713-22, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23139121

ABSTRACT

In this paper, we describe the antinociceptive activity, molecular modeling and in silico ADMET screening of a series of sulphonyl-hydrazone and sulphonamide imidobenzene derivatives. Among these compounds, the sulphonyl-hydrazones 9 and 11 showed the most potent analgesic activity (ID(50) = 5.1 and 6.8 µmol/kg, respectively). Interestingly, all derivatives evaluated in this study have a better analgesic profile than the control drugs, acetyl salicylic acid and acetaminophen. Derivative 9 was the most promising compound; with a level of activity that was 24 times higher than the control drugs. Our SAR study showed a relationship among the distribution of the frontier orbital HOMO coefficients, HOMO-LUMO energy gap of these molecules and their reactivity. The best analgesic compounds (including 6, 9, 10, 11 and 12) fulfilled the Lipinski "rule-of-five", which is theoretically important for good drug absorption and permeation.


Subject(s)
Analgesics/pharmacology , Drug Design , Hydrazones/pharmacology , Imides/pharmacology , Sulfonamides/pharmacology , Analgesics/chemical synthesis , Analgesics/chemistry , Analgesics/therapeutic use , Animals , Disease Models, Animal , Hydrazones/chemical synthesis , Hydrazones/chemistry , Hydrazones/therapeutic use , Hydrogen Bonding , Hydrophobic and Hydrophilic Interactions , Imides/chemical synthesis , Imides/chemistry , Imides/therapeutic use , Mice , Models, Molecular , Molecular Structure , Pain/drug therapy , Structure-Activity Relationship , Sulfonamides/chemical synthesis , Sulfonamides/chemistry , Sulfonamides/therapeutic use
SELECTION OF CITATIONS
SEARCH DETAIL
...