ABSTRACT
Con el incremento de la esperanza de vida de la población, las personas mayores de 65años son un grupo cada vez más prevalente, con el consiguiente aumento de patologías crónicas asociadas, desencadenando un escenario de gran impacto sociosanitario. Durante el proceso de envejecimiento se producen cambios tanto estructurales como funcionales en el riñón y en el sistema cardiovascular que condicionan la aparición de alteraciones de la función renal e hipertensión arterial, problemas de salud de primer orden en la actualidad. El objetivo de esta revisión es describir los cambios en la función renal y en la regulación de la presión arterial con el envejecimiento, su impacto clínico, en especial en la morbimortalidad de los individuos, y los enfoques terapéuticos ante estas alteraciones, orientados a las características particulares de este grupo poblacional. (AU)
Individuals over 65years are the fastest expanding population throughout the world, due to the increase in human life expectancy. This growing geriatric population, with increasingly associated chronic diseases, has relevant medical, social, and economic impact. Aging is characterized by progressive structural and functional changes in the kidney and in the cardiovascular system, leading to decline in renal function and hypertension. The purpose of this review is to describe the aging-related renal changes and blood pressure regulation during the aging process, their impact with regards to morbidity and mortality in these patients, and to summarize the most appropriate therapeutic approaches in these situations based on the particularities of this population group. (AU)
Subject(s)
Humans , Aging , Hypertension/diagnosis , Hypertension/epidemiology , Kidney/physiology , Renal Insufficiency, Chronic/diagnosis , Renal Insufficiency, Chronic/epidemiology , Renal Insufficiency, Chronic/therapy , Life Expectancy , AgedABSTRACT
Individuals over 65years are the fastest expanding population throughout the world, due to the increase in human life expectancy. This growing geriatric population, with increasingly associated chronic diseases, has relevant medical, social, and economic impact. Aging is characterized by progressive structural and functional changes in the kidney and in the cardiovascular system, leading to decline in renal function and hypertension. The purpose of this review is to describe the aging-related renal changes and blood pressure regulation during the aging process, their impact with regards to morbidity and mortality in these patients, and to summarize the most appropriate therapeutic approaches in these situations based on the particularities of this population group.
