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2.
Bull World Health Organ ; 94(5): 331-9, 2016 May 01.
Article in English | MEDLINE | ID: mdl-27147763

ABSTRACT

OBJECTIVE: To determine the impact of intimate partner violence against women on children's growth and nutritional status in low- and middle-income countries. METHODS: We pooled records from 42 demographic and health surveys in 29 countries. Data on maternal lifetime exposure to physical or sexual violence by an intimate partner, socioeconomic and demographic characteristics were collected. We used logistic regression models to determine the association between intimate partner violence and child stunting and wasting. FINDINGS: Prior exposure to intimate partner violence was reported by 69 652 (34.1%) of the 204 159 ever-married women included in our analysis. After adjusting for a range of characteristics, stunting in children was found to be positively associated with maternal lifetime exposure to only physical (adjusted odds ratio, aOR: 1.11; 95% confidence interval, CI: 1.09-1.14) or sexual intimate partner violence (aOR: 1.09; 95% CI: 1.05-1.13) and to both forms of such violence (aOR: 1.10; 95% CI: 1.05-1.14). The associations between stunting and intimate partner violence were stronger in urban areas than in rural ones, for mothers who had low levels of education than for women with higher levels of education, and in middle-income countries than in low-income countries. We also found a small negative association between wasting and intimate partner violence (aOR: 0.94; 95%CI: 0.90-0.98). CONCLUSION: Intimate partner violence against women remains common in low- and middle-income countries and is highly detrimental to women and to the growth of the affected women's children. Policy and programme efforts are needed to reduce the prevalence and impact of such violence.


Subject(s)
Child Nutrition Disorders/epidemiology , Spouse Abuse/statistics & numerical data , Adolescent , Adult , Child , Child, Preschool , Cross-Sectional Studies , Educational Status , Female , Health Surveys , Humans , Infant , Infant, Newborn , Male , Middle Aged , Odds Ratio , Prevalence , Residence Characteristics , Risk Factors , Socioeconomic Factors , Young Adult
3.
J Epidemiol Community Health ; 70(8): 784-90, 2016 Aug.
Article in English | MEDLINE | ID: mdl-26826211

ABSTRACT

BACKGROUND: An estimated 151 million children worldwide have lost one or both parents (UNICEF). Although a considerable literature has documented the impact of parental loss on children's emotional development, to date there are mixed findings regarding the potential effect of orphanhood on children's physical growth. The aim of the study is to examine the association between orphanhood (maternal, paternal or both) on childhood stunting status, accounting for living arrangement. METHODS: We combine nationally representative data from 84 Demographic Health Surveys for 49 low-income and middle-income countries (LMICs). Data from 222 690 children aged 0-23 months were included in the analytical sample. We show pooled estimates from multiple analysis models, as well as models examining the role of the surviving parent's residence and household structure. RESULTS: In fully adjusted models, maternal orphans were found to have an increased risk of stunting (RR 1.3, 95% CI 1.2 to 1.4) compared to children with two living parents. The stratified models demonstrated that the greatest risk was observed for maternal orphans whose surviving fathers did not live with the child (RR 1.4, 95% CI 1.3 to 1.6). CONCLUSIONS: Early orphanhood constitutes a major risk for children's physical development in LMICs. However, the results suggest that the adverse effects of a parental loss can be mitigated if appropriate support is provided, indicating the potential benefits of the surviving parents staying with their children. The benefits of targeted social policies aimed at single fathers and grandparents supporting orphans may be significant.


Subject(s)
Caregivers , Child, Orphaned , Growth Disorders , Family Characteristics , Female , Humans , Infant , Infant, Newborn , Male , Poverty
4.
Pediatr Blood Cancer ; 63(5): 813-7, 2016 May.
Article in English | MEDLINE | ID: mdl-26785111

ABSTRACT

BACKGROUND: More than 85% of pediatric cancer cases and 95% of deaths occur in resource-poor countries that use less than 5% of the world's health resources. In the developed world, approximately 81% of children with cancer can be cured. Models applicable in the most resource-poor settings are needed to address global inequities in pediatric cancer treatment. PROCEDURE: Between 2006 and 2011, a cohort of children received cancer therapy using a new approach in rural Rwanda. Children were managed by a team of a Rwandan generalist doctor, Rwandan nurse case manager, Rwanda-based US-trained pediatrician, and US-based pediatric oncologist. Biopsies and staging studies were obtained in-country. Pathologic diagnoses were made at US or European laboratories. Rwanda-based clinicians and the pediatric oncologist jointly generated treatment plans by telephone and email. RESULTS: Treatment was provided to 24 patients. Diagnoses included lymphomas (n = 10), sarcomas (n = 9), leukemias (n = 2), and other malignancies (n = 3). Standard chemotherapy regimens included CHOP, ABVD, VA, COP/COMP, and actino-VAC. Thirteen patients were in remission at the completion of data collection. Two succumbed to treatment complications and nine had progressive disease. There were no patients who abandoned treatment. The mean overall survival was 31 months and mean disease-free survival was 18 months. CONCLUSIONS: These data suggest that chemotherapy can be administered with curative intent to a subset of cancer patients in this setting. This approach provides a platform for pediatric cancer care models, relying on local physicians collaborating with remote specialist consultants to deliver subspecialty care in resource-poor settings.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Models, Biological , Neoplasms , Rural Population , Adolescent , Child , Child, Preschool , Disease-Free Survival , Female , Humans , Infant , Male , Neoplasm Staging , Neoplasms/diagnosis , Neoplasms/drug therapy , Neoplasms/mortality , Rwanda/epidemiology , Survival Rate
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