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Arkh Anat Gistol Embriol ; 69(9): 62-73, 1975 Sep.
Article in Russian | MEDLINE | ID: mdl-1191075

ABSTRACT

The present work is a fragment of the author's complex study of replantation of an extremity in experiment. Experiments on reproduction of the model of traumatic shock with acute loss of blood under conditions of muscle relaxation proposed by Yu. V. Kiprenski were performed in 15 dogs and 10 cats. It was established that in animals dead as a result of shock there appeared severe disorders of microcirculation in tissues and organs. They were characterized by a pronounced spasm of the vessels of the arteriolar link and dilatation of the venular and lymph collectors of the microcirculation bed. Simultaneously a great number of arterio-venular anastomoses were opened through which the arterial blood was shunted partly to avoid constricted capillaries. In the vessels of the venular link of the microcirculatory bed there appeared aggregations of formed elements of blood and microemboles. In absence of specific complex therapy, as it was in our experiments, the animals die of shock within the period from 17 min to 5 hour 20 min.


Subject(s)
Connective Tissue/physiopathology , Hemorrhage/physiopathology , Microcirculation/physiopathology , Shock, Traumatic/physiopathology , Acute Disease , Amputation, Traumatic/physiopathology , Animals , Brain/blood supply , Cats , Dogs , Female , Intestine, Large/blood supply , Intestine, Small/blood supply , Kidney/blood supply , Ligaments/blood supply , Lymphatic System/physiopathology , Male , Mesenteric Arteries/physiopathology , Mesenteric Veins/physiopathology , Omentum/blood supply , Pericardium/blood supply , Pleura/blood supply , Time Factors
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