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1.
Biomed Eng Lett ; 14(4): 649-661, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38946810

ABSTRACT

The accurate prediction of heart disease is crucial in the field of medicine. While convolutional neural networks have shown remarkable precision in heart disease prediction, they are often perceived as opaque models due to their complex internal workings. This paper introduces a novel method, named Extraction of Classification Rules from Convolutional Neural Network (ECRCNN), aimed at extracting rules from convolutional neural networks to enhance interpretability in heart disease prediction. The ECRCNN algorithm analyses updated kernels to derive understandable rules from convolutional neural networks, providing valuable insights into the contributing factors of heart disease. The algorithm's performance is assessed using the Statlog (Heart) dataset from the University of California, Irvine's repository. Experimental results underscore the effectiveness of the ECRCNN algorithm in predicting heart disease and extracting meaningful rules. The extracted rules can assist healthcare professionals in making precise diagnoses and formulating targeted treatment plans. In summary, the proposed method bridges the gap between the high accuracy of convolutional neural networks and the interpretability necessary for informed decision-making in heart disease prediction.

2.
Comput Methods Biomech Biomed Engin ; 26(5): 527-539, 2023 Apr.
Article in English | MEDLINE | ID: mdl-35587795

ABSTRACT

Parkinson's disease (PD) is a common progressive neurodegenerative disorder that occurs due to corrosion of the substantianigra, located in the thalamic region of the human brain, and is responsible for the transmission of neural signals throughout the human body using brain chemical, termed as "dopamine." Diagnosis of PD is difficult, as it is often affected by the characteristics of the medical data of the patients, which include the presence of various indicators, imbalance cases of patients' data records, similar cases of healthy/affected persons, etc. Hence, sometimes the process of diagnosis may also be affected by human error. To overcome this problem some intelligent models have been proposed; however, most of them are single classifier-based models and due to this these models cannot handle noisy and imbalanced data properly and thus sometimes overfit the model. To reduce bias and variance, and to avoid overfitting of a single classifier-based model, this paper proposes an ensemble-based PD diagnosis model, named Ensembled Expert System for Diagnosis of Parkinson's Disease (EESDPD) with relevant features and a simple stacking ensemble technique. The proposed EESDPD aggregates diverse assumptions for making the prediction. The performance of the proposed EESDPD is compared with the performances of logistic regression, SVM, Naïve Bayes, Random Forest, XGBoost, simple Decision Tree, B-TDS-PD and B-TESM-PD in terms of classification accuracy, precision, recall and F1-score measures.


Subject(s)
Algorithms , Parkinson Disease , Humans , Parkinson Disease/diagnosis , Bayes Theorem , Brain , Support Vector Machine
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