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J Vasc Surg ; 37(6): 1234-9, 2003 Jun.
Article in English | MEDLINE | ID: mdl-12764270

ABSTRACT

OBJECTIVES: Carotid artery stenting (CAS) has been recommended as an alternative to carotid endarterectomy (CEA) by some clinicians. However, recently published clinical trials have reported 30-day stroke and death rates of 10% to 12%. This prompted review of our experience with CAS in patients at high risk, to document our results and guide further use of CAS. METHODS: From September 1996 to the present, we performed 114 consecutive CAS procedures in 105 patients. Sixty-three patients were men (60%) and 42 patients were women (40%), with mean age of 70 years (range, 45-93 years). Indications for CAS included recurrent stenosis after previous CEA in 74 patients (65%), primary lesions in 32 patients at high risk (28%), and carotid stenosis with previous ipsilateral radiation therapy in 8 patients (7%). Asymptomatic stenosis (>80%) was managed in 70 patients (61%), and symptomatic lesions (>50%) were treated in 44 patients (39%). RESULTS: CAS was technically successful in all patients. Mean severity of stenosis before CAS was 87% +/- 6%, compared with 9% +/- 4% after CAS. Two patients (1.9%) died, 1 of reperfusion-intracerebral hemorrhage and 1 of myocardial infarction 10 days after discharge; and 1 patient (0.95%) had a stroke (retinal infarction), for a 30-day stroke and death rate of 2.85%. Two patients (1.9%) had transient neurologic events. No cranial nerve deficits were noted. No neurologic complications have been noted in the last 27 patients (26%). CONCLUSIONS: A 30-day stroke and death rate of 2.85% in our experience demonstrates acceptability of CAS as an alternative to repeat operation or primary CEA in patients at high risk or in patients with radiation-induced stenosis. We recommend further clinical investigation of CAS and participation in clinical trials by vascular surgeons.


Subject(s)
Blood Vessel Prosthesis Implantation/adverse effects , Carotid Stenosis/mortality , Carotid Stenosis/surgery , Postoperative Complications , Stents/adverse effects , Stroke/etiology , Stroke/mortality , Aged , Aged, 80 and over , Carotid Stenosis/diagnostic imaging , Cohort Studies , Female , Follow-Up Studies , Humans , Male , Middle Aged , Outcome Assessment, Health Care , Radiography , Retrospective Studies , Risk Assessment , Severity of Illness Index , Stroke/diagnostic imaging , Survival Rate , Time Factors
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