ABSTRACT
The purpose of this article is to report the results of a programme for prevention of mother-to-child transmission (PMCT) of HIV conducted from 1999 to 2002 by the PNLS in Abidjan, Ivory Coast. This programme was supported by grants from the Fonds de solidarité international (FSTI) and the Glaxo Smith Kline (GSK) Foundation. After pre- and posttest counselling, pregnant women from 4 PMI centres underwent screening for HIV. Seropositive women were offered short course AZT and the possibility of financial assistance for breast-feeding. All programme activities were carried out in close cooperation with association members. A total of 22466 tests were given and 18116 women returned for results. Among the 1829 seropositive women to whom PMCT intervention was proposed, 667 received short course AZT. The rate of transmission at 18 months was 162%. In addition 69 mothers and 28 children eligible for ARV therapy benefited from tritherapy. Limiting factors, at each phase, and efficacy of intervention were analyzed.
Subject(s)
HIV Infections/prevention & control , HIV Infections/transmission , Infectious Disease Transmission, Vertical/prevention & control , Pregnancy Complications, Infectious , Breast Feeding , Cote d'Ivoire , Female , HIV Seropositivity , Humans , Infant , Pregnancy , Zidovudine/administration & dosageABSTRACT
Cet article relate le bilan du programme de prevention de la transmission du VIH de la mere a l'enfant mene par le PNLS de 1999 a 2003 a Abidjan avec le soutien du Fonds de solidarite therapeutique international (FSTI) et de la Fondation Glaxo Smith Kline (GSK). Apres un conseil individuel pre et post test; les femmes enceintes de 4 centres PMI pouvaient etre depistees pour le VIH. Aux femmes seropositives etait propose un regime court AZT puis; pour celles qui le choisissaient; le financement de l'allaitement artificiel. Toutes ces activites etaient menees avec une forte cooperation des membres d'associations. Sur la periode consideree 22 466 tests ont ete effectues et 18 116 femmes sont venues chercher leur resultat. Parmi les 1 829 femmes seropositives a qui l'intervention de PTME a ete proposee; 667 ont beneficie du regime court AZT. Le taux de transmission a 18 mois est de 16;2. Par ailleurs 69 meres et 28 enfants eligibles au traitement ARV ont ete mis sous tritherapie. Les facteurs limitant; a chaque etape; l'efficacite de l'intervention ont ete analyses
