ABSTRACT
The presence of Chlamydia trachomatis and human papillomavirus (HPV) was evaluated by PCR technique in 189 sexually active women, between 15 and 58 years old, with cytological abnormalities in their uterine cervical epithelium and belonging to a region of Argentina with high incidence of cervical cancer. Risk factors in relation to chlamydial infection were also analyzed. Total prevalence for C. trachomatis infection was 24.9%, but there was a significant difference between prevalence in low socio-economical level (32.9%) and high or medium socio-economical level (17.7%). Total prevalence for DNA of HPV was 52.9%, but women infected with C. trachomatis showed a higher risk for viral infection than non-infected ones (OR = 2.27 / CI 95% = 1.10-4.73), with statistical significant difference (p = 0.016).(AU)
Subject(s)
Adolescent , Adult , Female , Humans , Middle Aged , Cervix Uteri/microbiology , Chlamydia Infections/epidemiology , Chlamydia trachomatis , Papillomaviridae , Papillomavirus Infections/epidemiology , Argentina/epidemiology , Carcinoma/diagnosis , Cervix Uteri/pathology , Cervix Uteri/virology , Chlamydia Infections/diagnosis , Chlamydia trachomatis/isolation & purification , Genotype , Papillomaviridae/isolation & purification , Papillomavirus Infections/diagnosis , Polymerase Chain Reaction , Polymorphism, Restriction Fragment Length , Prevalence , Risk Factors , Uterine Cervical Neoplasms/diagnosis , Vaginal SmearsABSTRACT
The presence of Chlamydia trachomatis and human papillomavirus (HPV) was evaluated by PCR technique in 189 sexually active women, between 15 and 58 years old, with cytological abnormalities in their uterine cervical epithelium and belonging to a region of Argentina with high incidence of cervical cancer. Risk factors in relation to chlamydial infection were also analyzed. Total prevalence for C. trachomatis infection was 24.9%, but there was a significant difference between prevalence in low socio-economical level (32.9%) and high or medium socio-economical level (17.7%). Total prevalence for DNA of HPV was 52.9%, but women infected with C. trachomatis showed a higher risk for viral infection than non-infected ones (OR = 2.27 / CI 95% = 1.10-4.73), with statistical significant difference (p = 0.016).(AU)
Subject(s)
Adolescent , Adult , Female , Humans , Middle Aged , Cervix Uteri/microbiology , Chlamydia Infections/epidemiology , Chlamydia trachomatis , Papillomaviridae , Papillomavirus Infections/epidemiology , Argentina/epidemiology , Carcinoma/diagnosis , Cervix Uteri/pathology , Cervix Uteri/virology , Chlamydia Infections/diagnosis , Chlamydia trachomatis/isolation & purification , Genotype , Papillomaviridae/isolation & purification , Papillomavirus Infections/diagnosis , Polymerase Chain Reaction , Polymorphism, Restriction Fragment Length , Prevalence , Risk Factors , Uterine Cervical Neoplasms/diagnosis , Vaginal SmearsABSTRACT
The presence of Chlamydia trachomatis and human papillomavirus (HPV) was evaluated by PCR technique in 189 sexually active women, between 15 and 58 years old, with cytological abnormalities in their uterine cervical epithelium and belonging to a region of Argentina with high incidence of cervical cancer. Risk factors in relation to chlamydial infection were also analyzed. Total prevalence for C. trachomatis infection was 24.9%, but there was a significant difference between prevalence in low socio-economical level (32.9%) and high or medium socio-economical level (17.7%). Total prevalence for DNA of HPV was 52.9%, but women infected with C. trachomatis showed a higher risk for viral infection than non-infected ones (OR = 2.27 / CI 95% = 1.10-4.73), with statistical significant difference (p = 0.016).
Subject(s)
Adolescent , Adult , Female , Humans , Middle Aged , Chlamydia trachomatis , Cervix Uteri/microbiology , Chlamydia Infections/epidemiology , Papillomavirus Infections/epidemiology , Papillomaviridae , Argentina/epidemiology , Carcinoma/diagnosis , Chlamydia trachomatis/isolation & purification , Cervix Uteri/pathology , Cervix Uteri/virology , Genotype , Chlamydia Infections/diagnosis , Papillomavirus Infections/diagnosis , Uterine Cervical Neoplasms/diagnosis , Polymerase Chain Reaction , Polymorphism, Restriction Fragment Length , Prevalence , Papillomaviridae/isolation & purification , Risk Factors , Vaginal SmearsABSTRACT
Noble-gas geochemistry is an important tool for understanding planetary processes from accretion to mantle dynamics and atmospheric formation. Central to much of the modelling of such processes is the crystal-melt partitioning of noble gases during mantle melting, magma ascent and near-surface degassing. Geochemists have traditionally considered the 'inert' noble gases to be extremely incompatible elements, with almost 100 per cent extraction efficiency from the solid phase during melting processes. Previously published experimental data on partitioning between crystalline silicates and melts has, however, suggested that noble gases approach compatible behaviour, and a significant proportion should therefore remain in the mantle during melt extraction. Here we present experimental data to show that noble gases are more incompatible than previously demonstrated, but not necessarily to the extent assumed or required by geochemical models. Independent atomistic computer simulations indicate that noble gases can be considered as species of 'zero charge' incorporated at crystal lattice sites. Together with the lattice strain model, this provides a theoretical framework with which to model noble-gas geochemistry as a function of residual mantle mineralogy.
