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Severe macrolide-resistant Mycoplasma pneumoniae pneumonia associated with macrolide failure.
Cheong, Kai-Ning; Chiu, Susan S; Chan, Betsy Wai-Ka; To, Kelvin Kai-Wang; Chan, Eunice Lai-Yin; Ho, Pak-Leung.
J Microbiol Immunol Infect ; 49(1): 127-30, 2016 Feb.
Article in English | MEDLINE | ID: mdl-25556047

ABSTRACT

We investigated differences in outcomes between 68 children hospitalized with macrolide-sensitive Mycoplasma pneumoniae pneumonia (MSMP group) and 25 children hospitalized with macrolide-resistant M. pneumoniae pneumonia (MRMP group). In the MRMP group, 19 children received macrolides and clinical failure occurred in six of which five had pneumonia progression during therapy.


Subject(s)
Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Drug Resistance, Bacterial , Macrolides/pharmacology , Macrolides/therapeutic use , Mycoplasma pneumoniae/drug effects , Pneumonia, Mycoplasma/diagnosis , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Male , Mycoplasma pneumoniae/isolation & purification , Pneumonia, Mycoplasma/drug therapy , Pneumonia, Mycoplasma/microbiology , Treatment Failure
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