ABSTRACT
Hepatitis E is an enterically transmitted and typically self-limited infection, that is caused by the hepatitis E virus. Hepatitis E viral infection has traditionally been considered an acute. Chronic hepatitis E is rare and occurs mainly in immunosuppressed individuals such as transplant recipients, HIV patients with low CD4 count and in patients with hematological malignancies receiving chemotherapy.
Subject(s)
Hematologic Neoplasms/diagnosis , Hepatitis E/diagnosis , HIV Infections/complications , Hepatitis E virus , Hepatitis, Chronic , HumansABSTRACT
Haemophagocytic lymphohistiocytosis (HLH) is a devastating syndrome due to uninhibited immune activation. Disseminated histoplasmosis is a rare cause of HLH. There have been few case reports and series demonstrating a relation between the two disease entities in immunosuppressed hosts. HLH secondary to disseminated histoplasmosis is even rarer in an immunocompetant host. We report a rare case of HLH triggered by disseminated histoplasmosis in an immunocompetant patient.