ABSTRACT
Aneurysmal bone cyst, commonly reported in the second and third decades of life, is characterized by a rapid growth pattern with resultant bony expansion and facial asymmetry. Interestingly, these lesions can occur in association with other primary bone pathologies, where they are referred to as "hybrid lesions" or "ABC-Plus." Their rarity, especially in the head and neck region, may pose a diagnostic challenge to clinicians. Following is a discussion of one such enigmatic lesion that includes description of a unique case of ABC-Plus that affected the right mandible of a young male.
Subject(s)
Bone Cysts, Aneurysmal/diagnosis , Fibroma, Ossifying/diagnosis , Mandibular Diseases/diagnosis , Mandibular Neoplasms/diagnosis , Adolescent , Biopsy , Diagnosis, Differential , Humans , Male , Paracentesis , Radiography, Panoramic , Tomography, X-Ray ComputedABSTRACT
Ionizing radiation has been known to induce malignant transformation in human beings. Radiation-induced sarcomas are a late sequel of radiation therapy. Most sarcomas have been reported to occur after exposure to a radiation dose of 55 Gray (Gy) and above, with a dose ranging from 16 to 112 Gys. Spindle cell sarcomas, arising after radiotherapy given to treat the carcinoma of head and neck region is a very uncommon sequel. This is a rare case report of spindle cell sarcoma of left maxilla, in a 24-year-old male, occurring as a late complication of radiotherapy with Cobalt-60 given for the treatment of retinoblastoma of the left eye 21 years back.
