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1.
Chin J Physiol ; 61(3): 181-187, 2018 Jun.
Article in English | MEDLINE | ID: mdl-29962178

ABSTRACT

High plasma triglyceride (TG) concentration in fasting state could cause hemorheological abnormality, thus increasing the incidence of metabolic diseases. Exercise has been reported to effectively reduce postprandial TG response. This study aimed to investigate whether a single bout of pre-prandial exercise can affect lipemia and hemorheological variables after a high-fat meal. Nine healthy young male subjects completed two experimental trials. The subjects walked for 1 h at 50% maximal oxygen uptake (V̇O2max) (the exercise, EX trial), or rested (the control, CON trial). In the next morning, the subjects consumed a high-fat meal, and the postprandial lipemia and hemorheological responses were monitored for 6 h. The results showed that postprandial plasma TG concentrations were significantly lower in the EX trial compared to the CON trial. The postprandial low-density lipoproteins (LDL) concentration declined in the first 2 h and then gradually returned to the baseline level in both trials. The postprandial blood viscosity also decreased in the CON trial. There was no significant difference in postprandial blood viscosity, red blood cell (RBC) deformation index and aggregation degree between the trials. There was no significant correlation between plasma TG concentration and blood viscosity. In conclusion, brisk walking effectively reduced postprandial TG concentration, but has no significant impact on postprandial blood viscosity, RBC deformation index and RBC aggregation index.


Subject(s)
Blood Viscosity , Dietary Fats/metabolism , Dyslipidemias/prevention & control , Exercise , Lipoproteins, LDL/blood , Postprandial Period , Triglycerides/blood , Biomarkers/blood , Dietary Fats/administration & dosage , Dyslipidemias/blood , Dyslipidemias/etiology , Dyslipidemias/physiopathology , Erythrocytes/metabolism , Healthy Volunteers , Humans , Male , Taiwan , Time Factors , Walking , Young Adult
2.
Nutrients ; 10(2)2018 Jan 29.
Article in English | MEDLINE | ID: mdl-29382142

ABSTRACT

Ingestion of low glycemic index (LGI) carbohydrate (CHO) before exercise induced less insulin response and higher fat oxidation than that of high GI (HGI) CHO during subsequent exercise. However, the effect on the subsequent postprandial lipid profile is still unclear. Therefore, the aim of this study was to investigate ingestion of CHO drinks with different GI using fructose and glucose before endurance exercise on the subsequent postprandial lipid profile. Eight healthy active males completed two experimental trials in randomized double-blind cross-over design. All participants ingested 500 mL CHO (75 g) solution either fructose (F) or glucose (G) before running on the treadmill at 60% VO2max for 1 h. Participants were asked to take an oral fat tolerance test (OFTT) immediately after the exercise. Blood samples were obtained for plasma and serum analysis. The F trial was significantly lower than the G trial in TG total area under the curve (AUC; 9.97 ± 3.64 vs. 10.91 ± 3.56 mmol × 6 h/L; p = 0.033) and incremental AUC (6.57 ± 2.46 vs. 7.14 ± 2.64 mmol/L × 6 h, p = 0.004). The current data suggested that a pre-exercise fructose drink showed a lower postprandial lipemia than a glucose drink after the subsequent high-fat meal.


Subject(s)
Exercise , Fructose/administration & dosage , Glucose/administration & dosage , Hyperlipidemias/blood , Postprandial Period , Blood Glucose/metabolism , Cholesterol/blood , Cross-Over Studies , Double-Blind Method , Exercise Test , Fatty Acids, Nonesterified/blood , Glycemic Index , Glycerol/blood , Humans , Insulin/blood , Male , Meals , Oxygen Consumption , Triglycerides/blood , Young Adult
3.
RSC Adv ; 8(58): 33030-33034, 2018 Sep 24.
Article in English | MEDLINE | ID: mdl-35548136

ABSTRACT

Novel Fe3C nanoparticles encapsulated with nitrogen-doped graphitic shells were synthesized by floating catalytic pyrolysis. Due to the short synthesis time and controllable pyrolytic temperature, the diameters of Fe3C core nanoparticles ranged from 5 to 15 nm (Fe3C@NGS900 prepared at 900 °C) and the average thickness of N-doped graphitic shells was ∼1.2 nm, leading to their high electrochemical performance: specific capacity of 1300 mA h g-1 at current density 0.2 A g-1, outstanding rate capability of 939 mA h g-1 at 3 A g-1, improved initial coulombic efficiency (Fe3C@NGS900: 72.1% vs. NGS900 (pure graphitic shells): 52%) for lithium ion batteries (LIBs), and impressive long-term cycle performance (1399 mA h g-1 maintained at 3 A g-1 after 500 cycles for LIBs; 214 mA h g-1 maintained at 1 A g-1 after 500 cycles for sodium ion batteries).

4.
J Nanosci Nanotechnol ; 15(4): 3111-6, 2015 Apr.
Article in English | MEDLINE | ID: mdl-26353545

ABSTRACT

We demonstrate a new sulfur (S)-doping templated approach to fabricate highly nanoporous graphitic nanocages (GNCs) by air-oxidizing the templates in the graphitic shells to create nanopores. Sulfur can be introduced, when Fe@C core-shell nanoparticles are prepared and then S-doped GNCs can be obtained by removing their ferrous cores. Due to removing S-template, both the specific surface area (from 540 to 850 m2 g(-1)) and the mesopore volume (from 0.44 to 0.9 cm3 g(-1)) of the graphitic nanocages have sharply risen. Its high specific surface area improves catalyst loading to provide more reaction electro-active sites while its high mesopore volume pro- motes molecule diffusion across the nanocages, making it an excellent material to support Pt/Ru catalysts for direct methanol fuel cells.

5.
Lipids Health Dis ; 13: 177, 2014 Nov 25.
Article in English | MEDLINE | ID: mdl-25424502

ABSTRACT

BACKGROUND: Aerobic exercise can decrease postprandial triglyceride (TG) concentrations but the relationship between exercise-induced energy deficits and postprandial lipemia is still unclear. The aim of the present study was to examine the effect of a single bout of aerobic exercise, with and without energy replacement, on postprandial lipemia and on peripheral blood mononuclear cell (PBMC) mRNA expression of very low density lipoprotein (VLDL) and low density lipoprotein (LDL) receptors and 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR). METHODS: Nine healthy male humans completed three two-day trials in a random order. On day 1, volunteers rested (CON), completed 60 minutes of treadmill walking at 50% of VO2peak (EX) or completed the same bout of walking but with the energy replaced afterwards with a glucose solution (EXG). On day 2, volunteers rested and consumed a high fat test meal in the morning. RESULTS: Total and incremental TG AUC were significantly lower on the EXG (P < 0.05) and EX (P < 0.05) trials than the CON trial with no difference between the two exercise trials. No significant difference was observed in VLDL or LDL receptor mRNA expression among the trials (P > 0.05). CONCLUSIONS: In conclusion, energy replacement by glucose did not affect the decrease in postprandial TG concentrations observed after moderate intensity exercise and exercise does not affect changes in PBMC HMGCR, VLDL and LDL receptor mRNA expression.


Subject(s)
Glucose/administration & dosage , Triglycerides/blood , Area Under Curve , Cholesterol, HDL/blood , Energy Metabolism , Fatty Acids, Nonesterified/blood , Gene Expression , Humans , Hydroxymethylglutaryl CoA Reductases/genetics , Hydroxymethylglutaryl CoA Reductases/metabolism , Leukocytes, Mononuclear/metabolism , Male , Physical Exertion , Postprandial Period , Receptors, LDL/genetics , Receptors, LDL/metabolism , Walking , Young Adult
6.
Shanghai Kou Qiang Yi Xue ; 11(4): 335-9, 2002 Dec.
Article in Chinese | MEDLINE | ID: mdl-14983374

ABSTRACT

OBJECTIVE: Some reports showed the benefits of dental implants coated with hydroxyapatite, while some other studies found no significant difference between HA-coated implants and non-coated implants. The present study was to examine the osseointegration of HA-coated and non-coated implants in dogs. METHODS: Twelve implants, 6 HA-coated and 6 non-coated were placed into mandibles of six dogs after teeth extraction. Animals were sacrificed after 1, 3, 6 months, respectively. Initial healing and the bone-implant interface were histomorphometrically assessed using light microscopy. RESULTS: All implants osseointegrated; however, the ingrowth and development of new bone tissue onto HA-coated implants surface were sooner than that of non-coated ones. The index of bone osseointegration of HA-coated implants was higher than that of non-coated ones. After 1,3,6 months the osseointegration of HA-coated implants were 71.68%, 86.81%, 90.19%; While the non-coated ones'were 53.26%, 66.16%, 68.72%. The differences of them were very significant. CONCLUSION: HA-coated implants enhanced initial bone tissue ingrowth and development and thus benefited the osseointegration of implants.

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