Bone bruise patterns in knee injuries: where are they found?

PURPOSE: Bone bruise represents an entity of occult bone lesions that can occur in the knee, causing knee pain and tenderness clinically. The aim of this study was to investigate the incidence and pattern of bone bruising seen in the anterior cruciate ligament (ACL) injury cohort, the non-ACL injury cohort, and between both cohorts. METHODS: We reviewed 710 knee magnetic resonance imagings performed over a 6-month period. Eighty-eight patients with prior history of a knee injury were identified. The mechanism of injury and other clinical findings was noted. RESULTS: Among these 88 patients, 58 patients had an associated ACL injury (31 had isolated ACL injuries; 27 had combined ACL and other ligamentous injuries). Among the 30 who had non-ACL injuries, 15 had either an MCL, LCL, or PCL injury. The remaining 15 patients had no associated ligament injury. With an ACL injury, the most common bone bruise sites are the lateral femur (74%) and lateral tibia (64%). Without an ACL injury, the pattern of bruising was more common in the lateral femur (69%) and medial tibia (37%). CONCLUSION: Bone bruises are important as previous studies have shown that they can cause persistent knee pain. Our study has shown that there are differences in pattern of bone bruising in knee injuries with or without ACL injuries.

Effect of cryoprotectant incubation time on handling properties of allogeneic tendons prepared for knee ligament reconstruction.

Soft tissue tendon allografts prepared for anterior cruciate ligament reconstruction are becoming increasingly popular; although concerns exist regarding increased long-term laxity and traumatic rupture rates. This qualitative study evaluated the tissue handling properties of human tibialis posterior tendons prepared using a patented process to improve allograft remodeling and ligamentization under differing cryoprotectant incubation times over 60-min rehydration. Tendons that had been incubated for 8 h had smaller diameters than those that were incubated for 2 h (8.5 +/- 1.5 mm vs. 9.1 +/- 1.3 mm, p = 0.02). Qualitative tissue handling property results indicated that the 8-h incubation had a negative affect on tissue color. Both incubation time and rehydration time influenced tensile stiffness, compressive resilience, and ease of tissue handling for allograft preparation with the 8-h group displaying poorer results. This study concludes that an 8-h cryoprotectant incubation time is detrimental to qualitative allogeniec tibialis posterior tendon properties. Both groups tended to improve with longer rehydration times, however the 8-h incubation group remained actively dehydrated as evidenced by its smaller diameter and poorer tissue handling properties. Suboptimally rehydrated tendons would be more likely to accrue damage during allograft preparation or during implantation.

The relationship of the lateral cord of the brachial plexus to the coracoid process during arthroscopic coracoid surgery: a dynamic cadaveric study.

BACKGROUND: Arthroscopic coracoid decompression is performed for coracoid impingement and has also been advocated for arthroscopic repair of tears of the subscapularis tendon, placing the lateral cord or the musculocutaneous nerve at risk of injury. The dynamic relationship of the lateral cord to the coracoid while the upper limb is in abduction and traction in the shoulder arthroscopy position is not clear. PURPOSE: The purpose of this study was to evaluate the dynamic relationship of the lateral cord of the brachial plexus to the coracoid process during varying degrees of upper limb abduction in traction. STUDY DESIGN: Descriptive laboratory study. METHODS AND MATERIALS: The musculocutaneous nerves of 15 fresh-frozen cadaveric shoulders were carefully dissected and identified without mobilization of the nerve. The musculocutaneous nerve was then injected with radiopaque contrast mixed with methylene blue. The contrast would infiltrate retrogradely into the lateral cord, minimizing mobilization of the lateral cord. The specimens were mounted in the lateral decubitus position with 4.5 kg of traction to the forearm and anteroposterior radiographs were taken at 30 degrees and 60 degrees of abduction. The nearest distance of the lateral cord to the coracoid process was measured off the radiographs and the displacement with increase in shoulder abduction was determined. RESULTS: The mean nearest distance between the lateral cord and the coracoid tip at 30 degrees of shoulder abduction was 26.6 +/- 5.2 mm and it moved nearer at 60 degrees of abduction to 23.4 +/- 5.1 mm; the difference of 3.2 mm was statistically significant (P < .0005, 95% confidence interval, 2.5-3.9 mm). The shortest distance measured was 14.4 mm in 1 specimen at 60 degrees of abduction. CONCLUSION: The lateral cord moved closer to the coracoid process at 60 degrees than at 30 degrees of abduction under traction during simulated shoulder arthroscopy position using the lateral decubitus position. CLINICAL RELEVANCE: The margin of safety for lateral cord injury during arthroscopic surgery around the coracoid process is improved with lower abduction angles in the lateral decubitus position.

Clinical evaluation of arthroscopic-assisted allograft meniscal transplantation.

INTRODUCTION: A meniscal deficient knee is at risk of early degenerative osteoarthritis. Allograft meniscal transplantation has been used to treat the meniscus deficiency to alleviate pain symptoms and to delay progression to arthritis. This case series aims to assess the postoperative outcomes of patients who have undergone meniscal allograft transplantation in our hospital. MATERIALS AND METHODS: This is a prospective clinical review of prospectively collected data of our Meniscal Transplantation Programme from 2004 to 2007. Twelve meniscal allografts were implanted in 12 males with symptomatic knees, using arthroscopically assisted techniques. Preoperative and postoperative assessments were conducted using the Visual Analogue Scale (VAS), Tegner Activity Level Scale, Lysholm Knee Scoring Scale, and 2000 International Knee Documentation Committee (IKDC) scoring systems. RESULTS: The mean age was 26.7 years with a mean follow-up of 17 months (range, 5 to 37). The VAS score for pain improved from 5.5 (3- 10) to 1.4 (0-2) [P <0.05], Tegner from 3 (2-5) to 5.9 (3-9) [P <0.05], Lysholm from 62.5 (27-88) to 88.6 (70-100) [P <0.05], IKDC Subjective Score from 50 (24-79) to 79.5 (56-95) [P <0.05]. Overall IKDC Knee Examination Grades revealed 10 nearly normal and 2 abnormal scores. CONCLUSIONS: This is the first series of allograft meniscal transplantation from Southeast Asia. Patient outcome evaluation via VAS, Tegner Activity Level Scale, Lysholm Knee Scoring Scale and 2000 IKDC Knee Evaluation Form showed improvement in symptoms and knee function after implantation.

Return to sports after anterior cruciate ligament reconstruction - a review of patients with minimum 5-year follow-up.

INTRODUCTION: It is difficult to counsel the anterior cruciate ligament (ACL) deficient patient considering surgical reconstruction on the likelihood of eventual return to sports as information on this is lacking, especially in the Asian context. We wanted to determine how many of our patients who had ACL surgery returned to their previous levels of sports, 5 years after their surgery. For those that had not returned to their previous levels of sports, we wanted to identify their reasons for not doing so. MATERIALS AND METHODS: Based on our inclusion criteria of a minimum 5-year follow-up after primary ACL reconstruction, 146 patients were identified for assessment. Sixty-four patients were successfully recalled. The mean age of our patients was 24.8 years (range, 18 to 40). The patients completed the Lysholm Knee, Tegner activity and the Subjective International Knee Documentation Committee (IKDC) questionnaires. Clinical examination of the operated knee was performed according to the Objective IKDC evaluation form and with a KT-1000 arthrometer. RESULTS: The mean Lysholm score was 85.2 and the mean subjective IKDC score was 79.5. 81.2% of our patients had normal or nearly normal knees (IKDC A or B) with the remaining 18.8% at IKDC grade C. The mean side-side difference for anterior translation using the KT-1000 arthrometer was 1.2 mm. The median pre-injury Tegner activity level was 7 and the median 5-year post-surgery Tegner activity level was 6. Nineteen patients did not return to their pre-injury sports levels because of social reasons and were excluded. From the remaining 45 patients, 28 patients (62.2%) returned to their previous level of sports and 17 patients (28.8%) did not return to their previous level of sports. Of whom, 9 (20%) said that they did not return due to fear of re-injury and the remaining 8 (17.8%) said they had not returned because of knee instability and pain. At 5 years, the subgroup of patients who had returned to sport had the best scores: Lysholm (88.5), subjective IKDC (84.6) and IKDC Grade A&B (89.3%). When we compared this with the subgroups that did not return to sport because of fear of re-injury and because of an unstable knee, we found that the difference in knee outcome scores between these 3 groups were statistically significant. CONCLUSION: Sixty-two per cent of our patients returned to their previous level of sport at 5 years after ACL reconstruction. Fear of reinjury is an important psychological factor for these patients not returning to sports. Our results would allow the attending surgeon to counsel the ACL deficient patient who is considering surgical reconstruction the likelihood of eventual return to sports.

Recurrent patellar dislocation: reappraising our approach to surgery.

INTRODUCTION: The management of recurrent traumatic patellar dislocation includes surgical realignment. There is no clear distinction whether proximal soft tissue or distal procedures produce superior results. However, distal realignment procedures are commonly associated with greater morbidity. We advocate a distal procedure only for cases which are more severe, such as the presence of patellar maltracking. MATERIALS AND METHODS: Between January 2002 and June 2007, all patients who had a history of traumatic patellar dislocation with recurrent symptoms and failed conservative management underwent surgical realignment. Patients who had evidence of lateral patellar subluxation on computed tomography (CT) scan were offered a distal realignment procedure using the Elmslie-Trillat or Roux Goldthwaite procedure. All other patients underwent proximal soft tissue medial patellofemoral ligament (MPFL) reconstruction. Pre and postoperative functional International Knee Documentation Committee (IKDC), Lysholm and Tegner score assessments were performed for a minimum follow-up period of 6 months. The mean scores for each group were analysed using the Wilcoxon Matched-Pairs Signed-Ranks test and the Mann-Whitney U test was used to evaluate the difference between the groups. RESULTS: A total of 23 patients underwent surgery for patellar realignment. Of whom, 14 patients had a distal realignment procedure while 9 patients had a proximal procedure of MPFL reconstruction. There was greater morbidity reported with distal realignment procedures. Pre and postoperative IKDC, Lysholm and Tegner scores showed significant improvement for both treatment arms. However, there was no significant difference between the improvement scores for both groups. CONCLUSION: Patients with significant patellar maltracking following traumatic patellar dislocation would benefit from distal realignment using the Elmslie-Trillat or Roux Goldthwaite procedure. Otherwise, a proximal soft tissue procedure involving MPFL reconstruction would be adequate. A management algorithm is proposed for clinical use.

Anatomic double bundle ACL reconstruction: a literature review.

With the abundance of anatomic double bundle ACL reconstruction techniques that currently exist and limited patient outcome data, one has to ask whether or not they should be used and if so, which one, and what is the learning curve for the average knee surgeon to become competent with the technique that they select? The purpose of this literature review is to summarize existing anatomic double bundle ACL reconstruction surgical and rehabilitation techniques and the clinical and biomechanical study evidence that currently exists. In choosing to perform anatomic double bundle ACL reconstruction we suggest that the knee surgeon should look for evidence of: (1) control of the pivot shift phenomenon, (2) improved transverse plane rotatory knee control during the performance of sports type movements, (3) a decreased likelihood of revision procedures either for ACL reconstruction or for treatment of associated primary or recurrent meniscal injuries, (4) improved patient self-reports of perceived function, satisfaction, and quality of life, and (5) radiographic evidence of a lower incidence and/or magnitude of osteoarthritic changes compared to conventional single bundle ACL reconstruction.

Evaluation of BioCorkscrew and Bioknotless RC suture anchor rotator cuff repair fixation: an in vitro biomechanical study.

This in vitro biomechanical study used cadaveric specimens to compare the rotator cuff repair fixation provided by BioCorkscrew and Bioknotless RC suture anchors. Three cm wide by 1-cm long full-thickness supraspinatus defects were repaired using either two BioCorkscrew suture anchors with combined vertical and horizontal mattress sutures (n = 7) or three Bioknotless RC suture anchors with simple sutures (n = 7). Therefore, the BioCorkscrew suture anchor group had two sutures per anchor (four total sutures), while the Bioknotless RC suture anchor group had one suture per anchor (three total sutures). Two-phase cyclic (5-100 N, 1,000 cycles and 5-180 N, 2,000 cycles) and load to failure tests (31 mm/s) were performed. Non-parametric statistics were used to compare group differences (P < 0.05). All of the BioCorkscrew group specimens (seven of seven) completed the two phase cyclic test regimen without failure or gapping >/= 5 mm, compared to only three of seven of the Bioknotless RC group (Fisher's Exact test = 0.03). Groups did not differ for repair site gapping during the 5-100 N cyclic test phase (Fisher's Exact test = 0.77), however more of the Bioknotless RC group displayed gapping >/= 5 mm during the 5-180 N cyclic test phase than the BioCorkscrew group (P = 0.02). The BioCorkscrew group also displayed greater yield load during load to failure testing (492.2 +/- 204 N vs. 296.4 +/- 155 N, P = 0.03). In this in vitro biomechanical study, the BioCorkscrew group with combined vertical and horizontal mattress sutures displayed greater cyclic test survival, less repair site gapping, and superior yield load compared to the Bioknotless RC group with simple sutures. These results in human cadaveric rotator cuff-humerus specimens suggest better immediate post-operative repair site strength and a reduced need for post-operative restrictions. Clinical studies are needed to determine how these rotator cuff repair modes withstand the forces of early rehabilitation and activities of daily living that potentially influence patient outcomes.

Self-reported patient outcomes at a minimum of 5 years after allograft anterior cruciate ligament reconstruction with or without medial meniscus transplantation: an age-, sex-, and activity level-matched comparison in patients aged approximately 50 years.

PURPOSE: Patient outcomes at a minimum of 5 years after medial meniscus transplantation and primary anterior cruciate ligament (ACL) reconstruction via allograft tissues were compared with those of age-, sex-, and activity level-matched patients who underwent meniscal repair or partial meniscectomy and primary ACL reconstruction via allograft tissues. METHODS: Eight patients (mean age, 51 +/- 5 years; three women and five men) at 5.5 +/- 0.5 years after medial meniscus transplantation and ACL reconstruction (group 1) and eight matched patients (mean age, 50 +/- 5 years; three women and five men) at 5.1 +/- 0.5 years after meniscal repair or partial meniscectomy and ACL reconstruction (group 2) completed the meniscus allograft clinical registry questionnaire, which combined the modified Lysholm knee scoring scale, the 1999 International Knee Documentation Committee subjective knee evaluation, and the knee pain level score on a 10-cm visual analog scale. RESULTS: Both groups displayed similar improvements in the modified Lysholm knee scoring scale components of pain, knee stability, squatting, stair climbing, and limping, as well as overall score (P < .05). Only group 2 displayed significant reductions in swelling. The groups displayed similar improvements in the 1999 International Knee Documentation Committee subjective knee evaluation components of sitting, rising from a chair, running, jumping, and stopping quickly, as well as overall score (P < .05). They also displayed significant improvements in the visual analog scale knee pain level score; however, group 1, which displayed greater preoperative pain levels, had considerably larger reductions. Most group 1 patients (7/8 [87.5%]) and all group 2 patients (8/8 [100%]) considered their surgery to be a success and would undergo the same procedure again if necessary. CONCLUSIONS: Although group 1 had greater preoperative knee pain levels, their pain levels at 5 years postoperatively were comparable to those in group 2. With the exception of swelling, comparable improvements were observed between groups for all other variables. LEVEL OF EVIDENCE: Level III, retrospective, case-control study.

Bilateral spontaneous rupture of the quadriceps tendon as an initial presentation of alkaptonuria--a case report.

Unilateral rupture of the quadriceps tendon is not uncommon, but bilateral spontaneous quadriceps tendon rupture is a rare occurrence and is usually associated with some underlying predisposing condition. We describe a case of a previously healthy patient who presents with bilateral spontaneous rupture of both quadriceps tendon. Investigations revealed that he had underlying alkaptonuria which was previously undiagnosed. Alkaptonuria is a rare inborn metabolic disease, which results in the derangement of homogentisic acid metabolism. Excessive accumulation of homogentisic acid is known to affect multiple organ systems, resulting in tendinopathy and arthropathy in the muscoskeletal system.

A simple method of meniscus repair using the arthroscopic outside-in technique.

We describe a simple method of arthroscopic outside-in meniscus repair that is easy to perform using readily available materials. The technique uses a 19-gauge venepuncture needle, a 16-gauge epidural needle, a No. 3 Prolene suture as a lasso loop, and No. 2 polydioxanone (PDS) sutures for meniscus repair. The venepuncture needle is used to puncture the meniscus from outside-in to deliver the Prolene lasso loop suture. The epidural needle is used to deliver one end of the PDS repair suture through the lasso loop. This suture end is captured by tightening the lasso loop, and delivered out of the joint by withdrawing the venepuncture needle. The epidural needle is kept in the joint. A second pass is made with the venepuncture needle at an appropriate site on the meniscus, and the lasso loop delivered. The other free end of the repair suture is threaded through the epidural needle and through the lasso loop. This other repair suture end is similarly captured and delivered out of the joint. The repair is completed by pulling on the free ends of the repair suture to apply it across the meniscus tear site, and secured by tying the suture to the capsule through a small incision.

Effect of lesion location on fixation strength of the meniscal viper repair system: an in vitro study using porcine menisci.

PURPOSE: The Meniscal Viper Repair System (Arthrex, Naples, FL) is a novel suture-based all-inside meniscal repair system. This study was performed to test whether the Meniscal Viper Repair System would provide superior fixation characteristics for vertical longitudinal meniscal lesions located closer to the periphery compared with those located further away from the periphery. METHODS: Vertical longitudinal lesions were created either 1 to 2 mm or 3 to 4 mm away from the periphery of porcine menisci. After repair with the Meniscal Viper Repair System, fixation characteristics were studied during cyclic (500 cycles, 5 to 50 N) and load to failure testing (5 mm/min) in a servo hydraulic device. RESULTS: Meniscal lesion repair location did not show significant differences in displacement or stiffness during cyclic testing. During load to failure testing, meniscal lesion repairs located 1 to 2 mm from the periphery showed superior load at failure (188.8 +/- 45.4 N) compared with repairs located 3 to 4 mm from the periphery (114.4 +/- 35.0 N) (P = .01). Stiffness and displacement during load to failure testing did not show statistically significant differences. CONCLUSIONS: The Meniscal Viper Repair System provides stronger meniscal repair strength when lesions are located within 1 to 2 mm of the periphery. CLINICAL RELEVANCE: The Meniscal Viper Repair System is better suited for repair of peripheral meniscal lesions located within 1 to 2 mm of the periphery. For lesions located in zone 2 (within the central 50%), careful assessment of their distance from the periphery is recommended. For lesions located more than 3 to 4 mm away from the periphery, alternative repair systems or augmentation with other devices may be prudent.

A biomechanical comparison of the FasT-Fix meniscal repair suture system and the RapidLoc device in cadaver meniscus.

PURPOSE: This biomechanical study compared the fixation characteristics of horizontally or vertically implanted FasT-Fix devices (Smith & Nephew, Endoscopy Division, Andover, MA) consisting of two 5-mm PLLA suture T-bar anchors with a pretied self-sliding knot (No. 0 nonabsorbable, USP, braided polyester suture material) and the RapidLoc device (Mitek Surgical Products, Westwood, MA) consisting of a PLLA T-bar anchor or "backstop," a connecting suture (No. 2 nonbiodegradable Ethibond; Ethicon, Somerville, NJ), and a PLLA grommet, for repairing posterior third lesions in human menisci. TYPE OF STUDY: Controlled laboratory biomechanical study. METHODS: After repair of a vertical longitudinal meniscus lesion with either vertically or horizontally implanted FasT-Fix devices or RapidLoc devices, 3 groups of 6 specimens underwent cyclic loading (5 mm/minute, cycling between 5 and 50 N at 1 Hz for 500 cycles) before load to failure testing on a servo hydraulic device. One-way analysis of variance and Tukey HSD post hoc tests were used to evaluate group differences (P < .05). RESULTS: The vertical FasT-Fix device group (3.2 +/- 0.49 mm) had less displacement after cyclic testing than either the horizontal FasT-Fix (4.4 +/- 0.73 mm, P = .003) or the RapidLoc (4.6 +/- 0.22 mm, P = .002) device groups. The vertical FasT-Fix device group had greater stiffness during cyclic testing (14.4 +/- 2.1 N/mm) than the horizontal FasT-Fix (10.4 +/- 1.6 N/mm, P = .0001) or the RapidLoc (9.7 +/- 0.44 N/mm, P = .0001) device groups. During load to failure testing, the vertical FasT-Fix group (125.3 +/- 39 N) had 28% greater strength than the horizontal FasT-Fix device group (89.7 +/- 14 N, P = .02) and 30% greater strength than the RapidLoc device group (87.1 +/- 13 N, P = .028), whereas displacement and stiffness did not show statistically significant group differences. CONCLUSIONS: The vertical FasT-Fix group had superior biomechanical characteristics for meniscal fixation during cyclic and load to failure testing compared with horizontal FasT-Fix or RapidLoc devices. CLINICAL RELEVANCE: Although the RapidLoc devices provided fixation characteristics comparable to horizontally implanted FasT-Fix devices, vertically implanted FasT-Fix devices may provide superior all-inside fixation.

Single femoral socket double-bundle anterior cruciate ligament reconstruction using tibialis anterior tendon: description of a new technique.

The native anterior cruciate ligament (ACL) has been shown to consist of 2 functional bundles with independent behavior throughout range of knee motion. Conventional arthroscopic ACL reconstruction techniques selectively recreate the anteromedial bundle of the native ACL only. Numerous studies have reported the failure to restore normal knee kinematics in an ACL-deficient knee using a single-bundle reconstruction. It has been suggested that by reconstructing both the anteromedial and posterolateral bundles of the ACL, more normal knee kinematics may be achieved. Several authors have described surgical techniques to recreate the 2 functional bundles and they range from using 2 femoral tunnels to using a single femoral tunnel with the other bundle passed over the top. This article describes a new technique of recreating the 2 functional bundles of the ACL with tibialis anterior tendon allograft using a single femoral socket.

Biomechanical comparison of the bioabsorbable RetroScrew system, BioScrew XtraLok with stress equalization tensioner, and 35-mm Delta Screws for tibialis anterior graft-tibial tunnel fixation in porcine tibiae.

BACKGROUND: Achieving effective soft tissue graft-tibial tunnel fixation remains problematic. HYPOTHESIS: No differences would exist for tibialis anterior graft-tibial tunnel fixation when comparing the RetroScrew System (20-mm retrograde screw, 17-mm antegrade screw), the 35-mm tapered Delta Screw (manual tensioning), and the 35-mm BioScrew XtraLok (applied using an instrumented tensioner). STUDY DESIGN: Controlled laboratory study. METHODS: Porcine tibiae (apparent bone mineral density, 1.3 g/cm(2)) and human tendon allografts were divided into 3 matched groups of 6 specimens each before cyclic (500 cycles, 50-250 N, 1 Hz) and load-to-failure (20 mm/min) tests. RESULTS: The BioScrew XtraLok (210.9 +/- 54.9 N/mm) and the 35-mm Delta Screw (224.3 +/- 43.7 N/mm) displayed superior stiffness to the RetroScrew System (114.1 +/- 23.3 N/mm) (P = .0004) during cyclic testing. The BioScrew XtraLok (1.0 +/- 0.2 mm) and the Delta Screw (0.9 +/- 0.2 mm) also displayed less displacement during cyclic testing than the RetroScrew System (1.8 +/- 0.5 mm) (P = .001). During load-to-failure testing, the BioScrew XtraLok withstood greater loads (1436.3 +/- 331.3 N) (P = .001) and displayed greater stiffness (323.6 +/- 56.8 N/mm) (P = .002) than the 35-mm Delta Screw (load, 1042.2 +/- 214.4 N; stiffness, 257.2 +/- 22.2 N/mm) and the RetroScrew System (load, 778.7 +/- 177.5 N; stiffness, 204.4 +/- 52.9 N/mm). CONCLUSION: The BioScrew XtraLok with instrumented tensioning displayed superior fixation to the RetroScrew System and the 35-mm Delta Screw applied with manual tensioning. CLINICAL RELEVANCE: The BioScrew XtraLok may provide superior soft tissue graft-tibial tunnel fixation. Further in vitro studies using human tissue and in vivo clinical studies are needed.

Knee dislocations-a retrospective study comparing operative versus closed immobilization treatment outcomes.

Controversies over operative versus closed immobilization of traumatic complex multiple ligamentous knee injury are still debated. The aim of our study is to evaluate the outcome of reconstructive vs non-reconstructive (closed immobilization) treatment outcomes. This is a retrospective review of cases seen at our institution. All cases admitted with a diagnosis of knee dislocation, defined as patients with multidirectional knee instability in the setting of trauma, were reviewed. Twenty-nine consecutive patients from January of 1996 to June of 2002 were reviewed. Twenty-six patients (89.7%) were successfully recalled and their functional outcome analyzed. Comparing the operated group (n=15, 57.7%) with closed immobilized patients (n=11, 42.3%), there was no statistical difference in the range of motion (mean difference 8.55 degrees , p=0.202). While the operated group had more flexion contracture (mean difference 3.9 degrees , p=0.002), they had better stability and better overall knee function as measured by the International Knee Documentation Committee (IKDC) score (the mean difference of IKDC score was 12.13, p=0.005). In the operated group of 15 patients, we compared partial repair (n=7) with complete repair of all torn ligaments (n=8). Superior results were noted in the group with complete repair of all structures, with comparable range of motion (mean difference 0.6 degrees , p=0.861) and flexion contractures (mean difference 1.0 degrees , p=0.795) but better stability and IKDC score (mean difference of IKDC score 13.6, p=0.003). Our conclusion is that operative treatment with complete repair of all torn structures produces the best overall knee function with better knee stability and patient satisfaction.

Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality.

BACKGROUND: Necrotizing fasciitis is a life-threatening soft-tissue infection primarily involving the superficial fascia. The present report describes the clinical presentation and microbiological characteristics of this condition as well as the determinants of mortality associated with this uncommon surgical emergency. METHODS: The medical records of eighty-nine consecutive patients who had been admitted to our institution for necrotizing fasciitis from January 1997 to August 2002 were reviewed retrospectively. RESULTS: The paucity of cutaneous findings early in the course of the disease makes the diagnosis difficult, and only thirteen of the eighty-nine patients had a diagnosis of necrotizing fasciitis at the time of admission. Preadmission treatment with antibiotics modified the initial clinical picture and often masked the severity of the underlying infection. Polymicrobial synergistic infection was the most common cause (forty-eight patients; 53.9%), with streptococci and enterobacteriaceae being the most common isolates. Group-A streptococcus was the most common cause of monomicrobial necrotizing fasciitis. The most common associated comorbidity was diabetes mellitus (sixty-three patients; 70.8%). Advanced age, two or more associated comorbidities, and a delay in surgery of more than twenty-four hours adversely affected the outcome. Multivariate analysis showed that only a delay in surgery of more than twenty-four hours was correlated with increased mortality (p < 0.05; relative risk = 9.4). CONCLUSIONS: Early operative débridement was demonstrated to reduce mortality among patients with this condition. A high index of suspicion is important in view of the paucity of specific cutaneous findings early in the course of the disease.